Trial of Extended Release Bupivacaine for Pain Relief After Surgery
Public ClinicalTrials.gov record NCT02574520. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Placebo-controlled (Part 1) or Active-controlled (Part 2) Trial of SABER® -Bupivacaine for the Management of Postoperative Pain Following Laparoscopic Cholecystectomy (PERSIST)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a research study of SABER® -Bupivacaine, an experimental medication designed to reduce pain for up to 3 days after surgery. Given once by the surgeon at the end of surgery, SABER® - Bupivacaine delivers a locally-acting pain reliever directly to the surgical wound. The purpose of this study is to measure how well it works in reducing pain after laparoscopic cholecystectomy (surgery to remove the gall bladder) and to investigate the safety of SABER®-Bupivacaine (its side effects).
Study identification
- NCT ID
- NCT02574520
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 399 participants
Conditions and interventions
Conditions
Interventions
- SABER-Bupivacaine (Part 1) Drug
- SABER-Bupivacaine (Part 2) Drug
- Saline Placebo Drug
- Bupivacaine HCl Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 31, 2015
- Primary completion
- May 31, 2017
- Completion
- Jul 31, 2017
- Last update posted
- Jul 12, 2021
2015 – 2017
United States locations
- U.S. sites
- 21
- U.S. states
- 12
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Durect Study Site 04 | Florence | Alabama | 35360 | — |
| Durect Study Site 03 | Sheffield | Alabama | 35660 | — |
| DURECT Study Site 24 | Arcadia | California | 91007 | — |
| Durect Study Site 15 | Fontana | California | 92335 | — |
| Durect Study Site 02 | Laguna Hills | California | 92653 | — |
| Durect Study Site 18 | Laguna Hills | California | 92653 | — |
| Durect Study Site 22 | Pensacola | Florida | 32503 | — |
| Durect Study Site 12 | Indianapolis | Indiana | 46202 | — |
| Durect Study Site 21 | Royal Oak | Michigan | 48073 | — |
| Durect Study Site 17 | Jackson | Mississippi | 39202 | — |
| Durect Study Site 16 | Las Vegas | Nevada | 89104 | — |
| Durect Study Site 20 | Las Vegas | Nevada | 89109 | — |
| Durect Study Site 05 | Stony Brook | New York | 11794 | — |
| Durect Study Site 13 | Durham | North Carolina | 27710 | — |
| Durect Study Site 09 | Cleveland | Ohio | 44106 | — |
| Durect Study Site 11 | Cleveland | Ohio | 44111 | — |
| Durect Study Site 07 | Cleveland | Ohio | 44195 | — |
| Durect Study Site 14 | Philadelphia | Pennsylvania | 19107 | — |
| Durect Study Site 08 | Houston | Texas | 77004 | — |
| DURECT Study Site 01 | Houston | Texas | 77043 | — |
| Durect Study Site 23 | Plano | Texas | 75093 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02574520, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 12, 2021 · Synced Sep 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02574520 live on ClinicalTrials.gov.