Evaluation of Efficacy and Safety of Brazikumab (MEDI2070) in Participants With Active, Moderate to Severe Crohn's Disease
Public ClinicalTrials.gov record NCT02574637. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b Double-Blind, Multi-Dose, Placebo-Controlled Study to Evaluate the Efficacy and Safety of MEDI2070 in Subjects With Moderate to Severe Crohn's Disease Who Have Failed or Are Intolerant to Anti-tumor Necrosis Factor-alpha Therapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A Phase 2b study to evaluate the efficacy and safety of brazikumab (MEDI2070) in participants with moderate to severe Crohn's disease who have failed or are intolerant to anti-tumor necrosis factor-alpha (anti-TNFα) therapy.
Study identification
- NCT ID
- NCT02574637
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 29 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 5, 2016 (Actual)
- Primary completion
- Jul 28, 2017 (Actual)
- Completion
- Jan 29, 2018 (Actual)
- Last update posted
- May 26, 2021
2016 – 2018
United States locations
- U.S. sites
- 52
- U.S. states
- 18
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Arthritis & Rheumatology Research, PLLC | Phoenix | Arizona | 85037 | — |
| Research Site | Phoenix | Arizona | 85037 | — |
| South Denver Gastroenterology, PC | Lone Tree | Colorado | 80124-5520 | — |
| Research Site | Lone Tree | Colorado | 80124 | — |
| Clinical Research of West Florida - Corporate | Clearwater | Florida | 33765 | — |
| Borland-Groover Clinic | Jacksonville | Florida | 32256 | — |
| Research Site | Jacksonville | Florida | 32256 | — |
| Advanced Pharma CR, LLC | Miami | Florida | 33147 | — |
| Research Site | Miami | Florida | 33147 | — |
| IMIC, Inc. | Palmetto Bay | Florida | 33157 | — |
| Research Site | Chicago | Illinois | 60637 | — |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| NorthShore University HealthSystem | Evanston | Illinois | 60201 | — |
| Research Site | Evanston | Illinois | 60201 | — |
| Indiana University | Indianapolis | Indiana | 46202 | — |
| Research Site | Indianapolis | Indiana | 46202 | — |
| Cotton-O'Neil Clinical Research Center, Digestive Health | Topeka | Kansas | 66606 | — |
| Research Site | Topeka | Kansas | 66606 | — |
| Graves Gilbert Clinic | Bowling Green | Kentucky | 42101 | — |
| Research Site | Bowling Green | Kentucky | 42101 | — |
| Research Site | Louisville | Kentucky | 40202 | — |
| University of Louisville | Louisville | Kentucky | 40202 | — |
| Clinical Trials of SW Louisiana, LLC | Lake Charles | Louisiana | 70601 | — |
| Research Site | Lake Charles | Louisiana | 70601 | — |
| Clinical Trials Management, LLC | Metairie | Louisiana | 70006 | — |
| Research Site | Metairie | Louisiana | 70006 | — |
| Research Site | Ann Arbor | Michigan | 48109 | — |
| University of Michigan Health System | Ann Arbor | Michigan | 48109 | — |
| Research Site | Southfield | Michigan | 48034 | — |
| Revival Research Institute, LLC | Southfield | Michigan | 48034 | — |
| Mayo Clinic - Rochester | Rochester | Minnesota | 55905 | — |
| Research Site | Rochester | Minnesota | 55905 | — |
| Ehrhardt Clinical Research, LLC | Belton | Missouri | 64012 | — |
| Research Site | Belton | Missouri | 64012 | — |
| New York University Medical Center | Great Neck | New York | 11021 | — |
| Premier Medical Group of the Hudson Valley, PC | Poughkeepsie | New York | 12601 | — |
| Research Site | Poughkeepsie | New York | 12601 | — |
| Research Site | Charlotte | North Carolina | 28205 | — |
| Clinical Inquest Center Ltd | Dayton | Ohio | 45409 | — |
| Research Site | Dayton | Ohio | 45409 | — |
| Donald Guthrie Foundation | Sayre | Pennsylvania | 18840 | — |
| Research Site | Sayre | Pennsylvania | 18840 | — |
| Erlanger Health System | Chattanooga | Tennessee | 37403 | — |
| Research Site | Chattanooga | Tennessee | 37403 | — |
| Research Site | Houston | Texas | 77030 | — |
| University of Texas Health Science Center at Houston | Houston | Texas | 77030 | — |
| Gastroenterology Research of America | Houston | Texas | 77098 | — |
| Research Site | Houston | Texas | 77098 | — |
| Baylor Research Institute | Temple | Texas | 76508-0001 | — |
| Research Site | Temple | Texas | 76508 | — |
| Allegiance Research Specialists, LLC | Milwaukee | Wisconsin | 53226 | — |
| Research Site | Wauwatosa | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 45 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02574637, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 26, 2021 · Synced Oct 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02574637 live on ClinicalTrials.gov.