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Completed Phase 3 Interventional Results available

Avelumab in First-line NSCLC (JAVELIN Lung 100)

ClinicalTrials.gov ID: NCT02576574

Public ClinicalTrials.gov record NCT02576574. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 8, 2026, 5:06 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III, Open-label, Multicenter Trial of Avelumab (MSB0010718C) Versus Platinum-based Doublet as a First-line Treatment of Recurrent or Stage IV PD-L1+NSCLC

Study identification

NCT ID
NCT02576574
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
EMD Serono Research & Development Institute, Inc.
Industry
Enrollment
1,214 participants

Conditions and interventions

Interventions

  • Avelumab Drug
  • Avelumab Weekly Drug
  • Carboplatin Drug
  • Cisplatin Drug
  • Gemcitabine Drug
  • Paclitaxel Drug
  • Pemetrexed Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 28, 2015
Primary completion
Dec 5, 2021
Completion
Jan 28, 2024
Last update posted
Jan 30, 2025

2015 – 2024

United States locations

U.S. sites
21
U.S. states
19
U.S. cities
21
Facility City State ZIP Site status
Clearview Cancer Institute Huntsville Alabama 35805
Arizona Center for Cancer Care Surprise Arizona 85374
Sharp Memorial Hospital San Diego California 92123
University Cancer Institute Boynton Beach Florida 33426
South Georgia Medical Center Valdosta Georgia 31602
Christus Cancer Treatment Center Shreveport Louisiana 71105
Henry Ford Hospital Detroit Michigan 48202
St. Vincent Frontier Cancer Center Billings Montana 59102
Nevada Cancer Research Foundation Las Vegas Nevada 89106
San Juan Oncology Associates Farmington New Mexico 87401
Novant Health Oncology Specialists Kernersville North Carolina 27284
Mercy Research Oklahoma City Oklahoma 73120
Kaiser Permanente Northwest Portland Oregon 97227
Lancaster Cancer Center Lancaster Pennsylvania 17605
Cookeville Regional Medical Center Cookeville Tennessee 38501
Thompson Cancer Survival Center Knoxville Tennessee 37916
Coastal Bend Cancer Center Corpus Christi Texas 78404
Oncology Consultants, P.A. Houston Texas 77030
University of Vermont Medical Center Burlington Vermont 05401-1473
Northwest Medical Specialties, PLLC Tacoma Washington 98405
Cheyenne Regional Medical Center Cheyenne Wyoming 82001

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 328 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02576574, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 30, 2025 · Synced May 8, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02576574 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →