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Withdrawn Phase 1 Interventional Accepts healthy volunteers

MicroRNA and MicroRNA Inhibitors Socket Study, Pilot Clinical Trial

ClinicalTrials.gov ID: NCT02579187

Public ClinicalTrials.gov record NCT02579187. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 5:08 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Efficacy of Local Delivery of MicroRNAs and MicroRNA Inhibitors in Promoting Osteogenesis and Modulating Local Inflammation: A Pilot Clinical Trial Using the Tooth Socket Model

Study identification

NCT ID
NCT02579187
Recruitment status
Withdrawn
Study type
Interventional
Phase
Phase 1
Lead sponsor
Gustavo Avila-Ortiz DDS, MS, PhD
Other
Enrollment
Not listed

Conditions and interventions

Interventions

  • tooth extraction Procedure
  • CBCT scan Radiation
  • Anesthesia Drug
  • clinical measurements Other
  • Biodegradable sponge (type I bovine collagen) Drug
  • 10µg of pSil-miR200c Drug
  • cross mattress suture Procedure
  • 10µg of PMIS miR200a plasmids Drug
  • 5µg of pSil-miR200c and 5µg of PMIS miR200a Drug
  • Blood Procedure
  • Photos/videos Other
  • Wound fluid Procedure
  • saliva Procedure
  • periapical xray Radiation
  • PVS impression Other

Procedure · Radiation · Drug + 1 more

Eligibility (public fields only)

Age range
25 Years to 65 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 30, 2025
Primary completion
Aug 31, 2030
Completion
Aug 31, 2030
Last update posted
Jul 16, 2019

2025 – 2030

United States locations

U.S. sites
1
U.S. states
1
U.S. cities
1
Facility City State ZIP Site status
UIowa Iowa City Iowa 52242

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02579187, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 16, 2019 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02579187 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →