Study to Evaluate the Clinical Efficacy and Safety of Subcutaneously Administered C1 Esterase Inhibitor for the Prevention of Angioedema Attacks in Adolescents and Adults With Hereditary Angioedema
Public ClinicalTrials.gov record NCT02584959. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-blind, Placebo-controlled, Two-period, Three-sequence, Partial Crossover Study to Evaluate the Efficacy and Safety of Subcutaneous Administration of 2000 IU of C1 Esterase Inhibitor [Human] Liquid for Injection for the Prevention of Angioedema Attacks in Adolescents and Adults With Hereditary Angioedema
Study identification
- NCT ID
- NCT02584959
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Shire
- Industry
- Enrollment
- 75 participants
Conditions and interventions
Conditions
Interventions
- C1 esterase inhibitor [human] liquid Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 31, 2015
- Primary completion
- Jul 23, 2017
- Completion
- Jul 23, 2017
- Last update posted
- Jun 7, 2021
2015 – 2017
United States locations
- U.S. sites
- 16
- U.S. states
- 12
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Medical Research of Arizona | Scottsdale | Arizona | 85251 | — |
| AIRE Medical of Los Angeles | Santa Monica | California | 90404 | — |
| Bay Area Allergy | Walnut Creek | California | 94598 | — |
| IMMUNOe Research Centers | Centennial | Colorado | 80112 | — |
| Asthma and Allergy Associates PC | Colorado Springs | Colorado | 80907 | — |
| Atlanta Allergy and Asthma Clinic | Marietta | Georgia | 30060 | — |
| Institute For Asthma and Allergy | Chevy Chase | Maryland | 20815 | — |
| Washington University | St Louis | Missouri | 63141 | — |
| Allergy Asthma and Immunology | Fair Lawn | New Jersey | 07410 | — |
| Allergy Treatment Center of New Jersey | Iselin | New Jersey | 08830 | — |
| Clinical Research of Charlotte | Charlotte | North Carolina | 28277 | — |
| Bernstein Clinical Research Center Inc | Cincinnati | Ohio | 45231 | — |
| Clinical Research Solutions | Middleburg Heights | Ohio | 44130 | — |
| Allergy Clinic of Tulsa | Tulsa | Oklahoma | 74133 | — |
| AARA Research Center | Dallas | Texas | 75231 | — |
| Premier Clinical Research | Spokane | Washington | 99202 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 11 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02584959, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 7, 2021 · Synced Jul 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02584959 live on ClinicalTrials.gov.