ClinicalTrials.gov record
Sustained Effect of Droxidopa in Symptomatic Neurogenic Orthostatic Hypotension
ClinicalTrials.gov ID: NCT02586623
Public ClinicalTrials.gov record NCT02586623. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
RESTORE: A Clinical Study of Patients With Symptomatic Neurogenic Orthostatic Hypotension to Assess Sustained Effects of Droxidopa Therapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To evaluate the time to treatment intervention in patients with Parkinson's Disease (PD), Multiple System Atrophy (MSA), Pure Autonomic Failure (PAF), Non-Diabetic Autonomic Neuropathy (NDAN) or Dopamine Beta Hydroxylase (DBH) Deficiency who have been previously stabilized with droxidopa therapy for symptoms of neurogenic orthostatic hypotension (NOH) (dizziness, light-headedness, or feelings that they are about to black out)
Study identification
- NCT ID
- NCT02586623
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 453 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 11, 2016 (Actual)
- Primary completion
- Jul 21, 2022 (Actual)
- Completion
- Sep 9, 2022 (Actual)
- Last update posted
- Aug 23, 2023
2016 – 2022
United States locations
- U.S. sites
- 168
- U.S. states
- 34
- U.S. cities
- 106
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| MDFirst Research - Chandler | Chandler | Arizona | 85226 | — |
| 21st Century Neurology | Phoenix | Arizona | 85004 | — |
| Movement Disorders Center of Arizona | Scottsdale | Arizona | 85258 | — |
| Center For Neurosciences | Tucson | Arizona | 85718 | — |
| Movement Disorder Clinic - The University of Arizona | Tucson | Arizona | 85724-5023 | — |
| University of Arizona Health Sciences Center, Department Of Neurology | Tucson | Arizona | 85724 | — |
| Arkansas Cardiology Clinic | Little Rock | Arkansas | 72205 | — |
| East Bay Physicians Medical Group | Berkeley | California | 94705 | — |
| Sutter East Bay Medical Foundation | Berkeley | California | 94705 | — |
| The Parkinson's and Movement Disorder Institute | Fountain Valley | California | 92708 | — |
| Behavioral Research Specialists, LLC | Glendale | California | 91206 | — |
| Loma Linda University Medical Center | Loma Linda | California | 92354 | — |
| University Of Southern California | Los Angeles | California | 90033 | — |
| Parkinson's Institute and Clinical Center | Mountain View | California | 94040 | — |
| Diverse Research Solutions, LLC | Oxnard | California | 93030 | — |
| Focilmed | Oxnard | California | 93030 | — |
| Parkinsons Disease & Movement Disorder of Silicon Valley | Palo Alto | California | 94301 | — |
| Neurosearch, Inc. - Pasedena | Pasadena | California | 91105 | — |
| Neurosearch, Inc. - Ventura | Pasadena | California | 91105 | — |
| SC3 Research Group | Pasadena | California | 91105 | — |
| Neurosearch, Inc. - Reseda | Reseda | California | 91335 | — |
| Radiological Associates of Sacramento | Sacramento | California | 95815 | — |
| Sutter Neuroscience | Sacramento | California | 95816 | — |
| The Parkinson's Institute and Clinical Center | Sunnyvale | California | 94085 | — |
| Neurosearch Inc. - Torrance | Torrance | California | 90505 | — |
| Colorado Springs Neurological Associates | Colorado Springs | Colorado | 80907 | — |
| Associated Neurologists, P.C. | Danbury | Connecticut | 06810 | — |
| Associated Neurologists of Southern Connecticut, P.C. | Fairfield | Connecticut | 06824 | — |
| Eastern Connecticut Neurology Specialists, LLC | Manchester | Connecticut | 06040 | — |
| Yale-New Haven Hospital | New Haven | Connecticut | 06510 | — |
| Yale Neurology / Hypertension Program | New Haven | Connecticut | 06519 | — |
| Yale University School Of Medicine | New Haven | Connecticut | 06520 | — |
| Christiana Care Neurology Specialists | Newark | Delaware | 19713 | — |
| Georgetown University | Washington D.C. | District of Columbia | 20007 | — |
| MedStar Georgetown-MedStar Georgetown Transplant Institute University Hospital (MGUH) | Washington D.C. | District of Columbia | 20007 | — |
| Neurology Offices Of South Florida | Boca Raton | Florida | 33428 | — |
| Parkinson's Disease And Movement Disorders Center of Boca Raton | Boca Raton | Florida | 33486 | — |
| South Florida Neurology Associates, P.A. | Boca Raton | Florida | 33487 | — |
| Innovative Research of West Florida | Clearwater | Florida | 33756 | — |
| UF Center for Movement Disorders and Neurorestoration | Gainesville | Florida | 32607 | — |
| Galiz Research | Hialeah | Florida | 33016 | — |
| SIH Research | Kissimmee | Florida | 34759 | — |
| Neurology Associates | Maitland | Florida | 32751 | — |
| Future Clinical Research | Miami | Florida | 33122 | — |
| Project 4 Research | Miami | Florida | 33125 | — |
| Premium Medical Research, Corp | Miami | Florida | 33126 | — |
| University Of Miami - Jackson Memorial Hospital, Dept. of Neurology | Miami | Florida | 33136 | — |
| Coral Way Research | Miami | Florida | 33155 | — |
| Florida Research Center | Miami | Florida | 33174 | — |
| Anchor Medical Research, LLC | Miami | Florida | 33176 | — |
| Novel Clinical Research Center, LLC | Miami | Florida | 33186 | — |
| Pro-Care Research Center, Corporation | Miami Gardens | Florida | 33014 | — |
| New Life Medical Research Center | Miami Lakes | Florida | 33014 | — |
| Neurostudies, Inc. | Port Charlotte | Florida | 33952 | — |
| Parkinson's Disease Treatment Center of Southwest Florida | Port Charlotte | Florida | 33952 | — |
| Eminance Medical & Clinical Research | Tampa | Florida | 33604 | — |
| University Of South Florida | Tampa | Florida | 33613 | — |
| USF Parkinson's & Movement Disorders Center | Tampa | Florida | 33613 | — |
| Vero Neurology | Vero Beach | Florida | 32960 | — |
| Geodyssey Research, LLC | Vero Beach | Florida | 32962 | — |
| Emory University | Atlanta | Georgia | 30329 | — |
| Georgia Regents University | Augusta | Georgia | 30912 | — |
| Neurological Center of North Georgia | Gainesville | Georgia | 30501 | — |
| The Neurological Center of North Georgia | Gainesville | Georgia | 30501 | — |
| Hawaii Pacific Neuroscience | Honolulu | Hawaii | 96817 | — |
| Northwestern Medical Group | Chicago | Illinois | 60611 | — |
| Cardio Specialists Group, Ltd., Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Rush University Medical Center - Department Of Cardiology | Chicago | Illinois | 60612 | — |
| Rush University Medical Center, Department of Neurology | Chicago | Illinois | 60612 | — |
| NorthShore Neurological Institute | Glenview | Illinois | 60026 | — |
| Central Dupage Hospital | Winfield | Illinois | 60190 | — |
| Northwestern Medicine Central DuPage Hospital | Winfield | Illinois | 60190 | — |
| American Health Network of Indiana | Avon | Indiana | 46123 | — |
| Fort Wayne Neurological Center | Fort Wayne | Indiana | 46804 | — |
| Franciscan Physician Network Indiana Heart Physicians | Indianapolis | Indiana | 46237 | — |
| Mid America Cardiology - University of Kansas | Kansas City | Kansas | 66160 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Louisiana Heart Center | Covington | Louisiana | 70433 | — |
| Maine Medical Partners Technology | Scarborough | Maine | 04074 | — |
| Mir Neurology | Hagerstown | Maryland | 21740 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Massachusetts General Hospital - Movement Disorders Clinic | Boston | Massachusetts | 02114 | — |
| Movement Disorders Clinic | Boston | Massachusetts | 02114 | — |
| Autonomic and Movement Disorders | Boston | Massachusetts | 02130 | — |
| Brigham and Women's Faulkner Hospital (BWFH) - Brigham & Women's Foot & Ankle Center | Boston | Massachusetts | 02130 | — |
| Michigan State University, Department of Neurology | East Lansing | Michigan | 48824 | — |
| Detroit Clinical Research Center | Farmington Hills | Michigan | 48334 | — |
| Michigan Center of Medical Research | Farmington Hills | Michigan | 48334 | — |
| Northern Michigan Neurology | Traverse City | Michigan | 49684 | — |
| Nothern Michigan Neurology | Traverse City | Michigan | 49684 | — |
| Henry Ford West Bloomfield Hospital | West Bloomfield | Michigan | 48322 | — |
| Platte Valley Medical Group | Kearney | Nebraska | 68845 | — |
| Methodist Physicians Clinic - Heart Consultants | Omaha | Nebraska | 68114 | — |
| MPC Heart Consultants | Omaha | Nebraska | 68114 | — |
| University Of Nebraska Medical Center | Omaha | Nebraska | 68198-8435 | — |
| The Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| JFK Neuroscience Institution | Edison | New Jersey | 08220 | — |
| Neuroscience Research Institute, LLC | Toms River | New Jersey | 08755 | — |
| SUNY Downstate Medical Center | Brooklyn | New York | 11203 | — |
| David L. Kreitzman MD, PC | Commack | New York | 11725 | — |
| Office of David L. Kreitzman, M.D., P.C. | Commack | New York | 11725 | — |
| Neurology Associates of West Chester | Hawthorne | New York | 10532 | — |
| Parker Jewish Institute for Health Care & Rehabilitation | New Hyde Park | New York | 11040 | — |
| Weill Cornell Medical College, Dept. of Neurology | New York | New York | 10021 | — |
| The Bendheim Parkinson and Movement Disorders Center | New York | New York | 10029 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| Project 4 Research, Inc., The Neurological Institute at Columbia University Medical Center | New York | New York | 10032 | — |
| The Neurological Institute at Columbia University Medical Center | New York | New York | 10032 | — |
| Parker Jewish Institute For Healthcare And Rehabilitation | New York | New York | 11542 | — |
| Island Neurological Associates | Plainview | New York | 11803 | — |
| Alpha Neurology | Staten Island | New York | 10306 | — |
| Helen Hayes Hospital | West Haverstraw | New York | 10093 | — |
| UBMD Neurology | Williamsville | New York | 14221 | — |
| Peak Clinical Trials | Apex | North Carolina | 27502 | — |
| The Neurological Institute, PA | Charlotte | North Carolina | 28204 | — |
| Neurosciences Institute | Charlotte | North Carolina | 28205 | — |
| Carolinas HealthCare System Neurosciences Institute | Charlotte | North Carolina | 28207 | — |
| Insight Neuroscience, LLC | Bellevue | Ohio | 44811 | — |
| Dayton Center for Neurological Disorders | Centerville | Ohio | 45459 | — |
| Riverhills Healthcare, Inc. | Cincinnati | Ohio | 45219 | — |
| Cleveland Clinic - Taussig Cancer Institute | Cleveland | Ohio | 44195 | — |
| Ohio Health Research Institute | Columbus | Ohio | 43214 | — |
| Ohio State University, Department of Neurology | Columbus | Ohio | 43221 | — |
| The Ohio State University | Columbus | Ohio | 43221 | — |
| Gardner-McMaster Parkinson Center - The University of Toledo | Toledo | Ohio | 43614 | — |
| Medical College of Ohio, Department of Neurology | Toledo | Ohio | 43614 | — |
| Baha Abu-Esheh, MD | Ardmore | Oklahoma | 73401 | — |
| CardioVoyage, LLC | Ardmore | Oklahoma | 73401 | — |
| COR Clinical Research, LLC | Oklahoma City | Oklahoma | 73103 | — |
| Legacy / Oregon Clinic Neurology | Portland | Oregon | 97210 | — |
| The Oregon Clinic | Portland | Oregon | 97210 | — |
| St. Luke's Neurology Associates | Bethlehem | Pennsylvania | 18018 | — |
| Penn State Hershey Children's Hospital | Hershey | Pennsylvania | 17025 | — |
| Penn State Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| Drexel Neurosciences Institute | Philadelphia | Pennsylvania | 19102 | — |
| University of Pennsylvania, Parkinson's Disease & Movement Disorders Center | Philadelphia | Pennsylvania | 19107 | — |
| University of Pittsburgh, Department of Neurology | Pittsburgh | Pennsylvania | 15213 | — |
| Dr. Umer Akbar MD, Office of | Providence | Rhode Island | 02903 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02905 | — |
| Vanderbilt University Autonomic Dysfunction Center - Clinical Trials Center | Nashville | Tennessee | 37232 | — |
| iMD Medical Center | Carrollton | Texas | 75006 | — |
| Sunbeam Clinical Research | Carrollton | Texas | 75006 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Elite Primary Care | Greenville | Texas | 75401 | — |
| Sunbeam Clinical Research | Greenville | Texas | 75401 | — |
| University of Texas Health Science Center at Houston | Houston | Texas | 77030 | — |
| Texas Institute of Cardiology, The Heartbeat Clinic | McKinney | Texas | 75069 | — |
| The Heartbeat Clinic | McKinney | Texas | 75069 | — |
| Sunbeam Clinical Research, LLC. | Prosper | Texas | 75078 | — |
| Central Texas Neurology Consultants | Round Rock | Texas | 78681 | — |
| Christus Research Institute | Tyler | Texas | 75701 | — |
| Clear Lake Specialties | Webster | Texas | 77598 | — |
| Bateman Home Center | Salt Lake City | Utah | 84102 | — |
| Inova Health Systems | Alexandria | Virginia | 22311 | — |
| Integrated Neurology Services, PLLC | Falls Church | Virginia | 22043 | — |
| Health Research of Hampton Roads-Norfolk, Inc | Norfolk | Virginia | 23502 | — |
| Sentara Neurology Specialists | Norfolk | Virginia | 23507 | — |
| Henrico Doctors Neurology Associates, LLC | Richmond | Virginia | 23226 | — |
| Carilion Clinic | Roanoke | Virginia | 24016 | — |
| Booth Gardner Parkinson's Care Center | Kirkland | Washington | 98034 | — |
| Northwest Neurology, Premier Clinical Research | Spokane | Washington | 99202 | — |
| Premeir Clinical Research | Spokane | Washington | 99202 | — |
| Aurora Medical Center | Grafton | Wisconsin | 53024 | — |
| Grafton Medical Office | Grafton | Wisconsin | 53024 | — |
| Aurora St. Luke's Medical Center | Milwaukee | Wisconsin | 53215 | — |
| Medical College of Wisconsin, Department of Neurology | Milwaukee | Wisconsin | 53226 | — |
| Aurora Sinai Medical Center-Arrhythmia Center | Milwaukee | Wisconsin | 53233 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02586623, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 23, 2023 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02586623 live on ClinicalTrials.gov.