Efficacy and Safety Study of DX-2930 to Prevent Acute Angioedema Attacks in Patients With Type I and Type II HAE
Public ClinicalTrials.gov record NCT02586805. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
HELP Study: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Efficacy and Safety Study to Evaluate DX-2930 For Long-Term Prophylaxis Against Acute Attacks of Hereditary Angioedema (HAE)
Study identification
- NCT ID
- NCT02586805
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Shire
- Industry
- Enrollment
- 125 participants
Conditions and interventions
Conditions
Interventions
- DX-2930 - 300mg/2wk Drug
- DX-2930 - 300mg/4wk Drug
- DX-2930 - 150mg/4wk Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 2, 2016
- Primary completion
- Apr 12, 2017
- Completion
- Apr 12, 2017
- Last update posted
- Jun 1, 2021
2016 – 2017
United States locations
- U.S. sites
- 31
- U.S. states
- 21
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinical Research Center of Alabama, LLC | Birmingham | Alabama | 35209 | — |
| Medical Research of Arizona | Scottsdale | Arizona | 85251 | — |
| UC San Diego School of Medicine | San Diego | California | 92122 | — |
| AIRE Medical of Los Angeles | Santa Monica | California | 90404 | — |
| Allergy & Asthma Clinical Research | Walnut Creek | California | 94598 | — |
| IMMUNOe International Health & Research Centers | Centennial | Colorado | 80112 | — |
| Asthma and Allergy Associates, P.C. | Colorado Springs | Colorado | 80907 | — |
| University of South Florida | Tampa | Florida | 33613 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Institute of Asthma & Allergy, P.C. | Chevy Chase | Maryland | 20815 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02421 | — |
| University of Michigan Hospital and Health System | Ann Arbor | Michigan | 48106 | — |
| Midwest Immunology Clinic | Plymouth | Minnesota | 55446 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Hudson-Essex Allergy, LLC | Belleville | New Jersey | 07109 | — |
| Atlantic Research Center, LLC | Ocean City | New Jersey | 07712 | — |
| Winthrop University Hospital | Mineola | New York | 11501 | — |
| The Mount Sinai Medical Center | New York | New York | 10029 | — |
| American Health Research | Charlotte | North Carolina | 28277 | — |
| Duke Asthma, Allergy and Airway Center | Durham | North Carolina | 27705 | — |
| Bernstein Clinical Research Center, LLC | Cincinnati | Ohio | 45231 | — |
| Optimed Research, LTD | Columbus | Ohio | 43235 | — |
| Toledo Institute of Clinical Research | Toledo | Ohio | 43617 | — |
| Penn State Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| Austin Regional Clinic | Austin | Texas | 78731 | — |
| AARA Research Center | Dallas | Texas | 75231 | — |
| Intermountain Clinical Research | Draper | Utah | 84020 | — |
| Allergy Associates of Utah | Murray | Utah | 84107 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23219 | — |
| Marycliff Allergy Specialists | Spokane | Washington | 99202 | — |
| Children's Hospital of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 10 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02586805, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 1, 2021 · Synced Jul 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02586805 live on ClinicalTrials.gov.