Beta-Blockers for the Prevention of Acute Exacerbations of Chronic Obstructive Pulmonary Disease
Public ClinicalTrials.gov record NCT02587351. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Beta-Blockers for the Prevention of Acute Exacerbations of COPD
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a multicenter, prospective, randomized, double-blind, placebo-controlled trial that will enroll 1028 patients with at least moderately severe COPD over a three year period and follow them at regular intervals for one year. The primary endpoint is time to first acute exacerbation. Secondary endpoints include rates and severity of COPD exacerbations, cardiovascular events, all-cause mortality, lung function, dyspnea, quality of life and metoprolol-related side effects.
Study identification
- NCT ID
- NCT02587351
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 532 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years to 84 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 1, 2016 (Actual)
- Primary completion
- Sep 1, 2019 (Actual)
- Completion
- Dec 1, 2019 (Actual)
- Last update posted
- Jan 25, 2021
2016 – 2019
United States locations
- U.S. sites
- 27
- U.S. states
- 16
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Birmingham, Alabama VA Medical | Birmingham | Alabama | 35233 | — |
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| University of California, San Francisco-Fresno | Fresno | California | 93701 | — |
| LA BioMed at Harbor-UCLA Medical Center | Los Angeles | California | 90502 | — |
| University of California at San Francisco | San Francisco | California | 94143 | — |
| National Jewish Medical & Research Center | Denver | Colorado | 80206 | — |
| North Florida/South Georgia Veterans Health System | Gainesville | Florida | 32608 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Louisiana State University | New Orleans | Louisiana | 70112 | — |
| University of Maryland Baltimore | Baltimore | Maryland | 21201 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| VA Ann Arbor Healthcare System | Ann Arbor | Michigan | 48105 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Veteran's Administration Medical Center | Minneapolis | Minnesota | 55417 | — |
| HealthPartners Research Foundation | Minneapolis | Minnesota | 55440 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| NewYork-Presbyterian Brooklyn Methodist Hospital | Brooklyn | New York | 11215 | — |
| New York Presbyterian/Queens | Flushing | New York | 11355 | — |
| Cornell University | Ithaca | New York | 14853 | — |
| Columbia University | New York | New York | 10027 | — |
| Cincinnati VA Medical Center | Cincinnati | Ohio | 45220 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Temple University Lung Center | Philadelphia | Pennsylvania | 19140 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | — |
| University of Utah Health Sciences Center | Salt Lake City | Utah | 84132-4701 | — |
| The University of Vermont | Burlington | Vermont | 05405 | — |
| University of Washington School of Medicine | Spokane | Washington | 99258 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02587351, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 25, 2021 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02587351 live on ClinicalTrials.gov.