Study to Evaluate Ibrutinib Combination Therapy in Patients With Selected Gastrointestinal and Genitourinary Tumors
Public ClinicalTrials.gov record NCT02599324. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1b/2 Study of Ibrutinib Combination Therapy in Selected Advanced Gastrointestinal and Genitourinary Tumors
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the safety, tolerability, and efficacy of single agent ibrutinib or the combination treatments of ibrutinib with everolimus, paclitaxel, docetaxel, pembrolizumab or cetuximab in selected advance gastrointestinal and genitourinary tumors.
Study identification
- NCT ID
- NCT02599324
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Enrollment
- 263 participants
Conditions and interventions
Conditions
Interventions
- ibrutinib Drug
- everolimus Drug
- paclitaxel Drug
- docetaxel Drug
- cetuximab Drug
- pembrolizumab Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 30, 2015
- Primary completion
- Aug 19, 2021
- Completion
- Aug 19, 2021
- Last update posted
- Nov 17, 2023
2015 – 2021
United States locations
- U.S. sites
- 44
- U.S. states
- 26
- U.S. cities
- 42
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clearview Cancer Institute /ID# 1128-0965 | Huntsville | Alabama | 35805 | — |
| Banner MD Anderson Cancer Center /ID# 1128-0802 | Gilbert | Arizona | 85234 | — |
| University of Arizona Cancer Center - Tucson /ID# 1128-1546 | Tucson | Arizona | 85724 | — |
| Alta Bates Comprehensive Cancer Center /ID# 1128-0135 | Berkeley | California | 94704 | — |
| St Marys Medical Center /ID# 1128-0969 | Daly City | California | 94015 | — |
| Duplicate_University of California San Diego/ Moores Cancer Center /ID# 1128-0241 | La Jolla | California | 92037-0845 | — |
| VA Long Beach Healthcare System /ID# 1128-0480 | Long Beach | California | 90822-5201 | — |
| USC Norris Cancer Center /ID# 1128-0209 | Los Angeles | California | 90033 | — |
| UC Irvine Medical Center - Chao Family Comprehensive Cancer Center /ID# 1128-0008 | Orange | California | 92868-3201 | — |
| Salinas Valley Memorial Hosp /ID# 1128-0482 | Salinas | California | 93901 | — |
| Premiere Oncology, A Medical Corporation /ID# 1128-1085 | Santa Monica | California | 90404 | — |
| St. Joseph Health /ID# 1128-1462 | Santa Rosa | California | 95403 | — |
| Gregory Smith, MD (Private Practice) /ID# 1128-0419 | St. Helena | California | 94574 | — |
| Whittingham Cancer Center at Norwalk Hospital /ID# 1128-0411 | Norwalk | Connecticut | 06856-3852 | — |
| Georgetown University Hospital /ID# 1128-0824 | Washington D.C. | District of Columbia | 20007 | — |
| Duplicate_Cancer Specialist of North Florida (CSNF) ( R ) /ID# 1128-1093 | Jacksonville | Florida | 32207 | — |
| IACT Health-Columbus /ID# 1128-1389 | Columbus | Georgia | 31904-8946 | — |
| Northshore Kellogg Cancer Center /ID# 1128-0484 | Evanston | Illinois | 60201 | — |
| Franciscan Health Indianapolis /ID# 1128-1125 | Indianapolis | Indiana | 46237 | — |
| Horizon Oncology Research Center /ID# 1128-0337 | Lafayette | Indiana | 47905 | — |
| University of Iowa Hospitals and Clinics /ID# 1128-0766 | Iowa City | Iowa | 52242 | — |
| The University of Kansas Cancer Center /ID# 1128-0706 | Fairway | Kansas | 66205 | — |
| East Jefferson General Hospital /ID# 1128-1084 | Metairie | Louisiana | 70006 | — |
| Duplicate_Tufts Medical Center /ID# 1128-0016 | Boston | Massachusetts | 02111-1552 | — |
| Barbara Ann Karmanos Cancer In /ID# 1128-0130 | Detroit | Michigan | 48201 | — |
| Henry Ford Hospital /ID# 1128-0195 | Detroit | Michigan | 48202 | — |
| Central Care Cancer Center /ID# 1128-1596 | Bolivar | Missouri | 65613 | — |
| Capital Region Medical Center /ID# 1128-1412 | Jefferson City | Missouri | 65102 | — |
| Nebraska Methodist Hospital /ID# 1128-0229 | Omaha | Nebraska | 68114 | — |
| New Jersey Center for Cancer Research /ID# 1128-0493 | Brick | New Jersey | 08724 | — |
| Duplicate_New Mexico Cancer Care Alliance /ID# 1128-0938 | Albuquerque | New Mexico | 87106 | — |
| San Juan Oncology Associates /ID# 1128-1020 | Farmington | New Mexico | 87401 | — |
| Memorial Sloan Kettering Cancer Center-Koch Center /ID# 1128-0091 | New York | New York | 10065-6007 | — |
| Wake Forest Univ HS /ID# 1128-0975 | Winston-Salem | North Carolina | 27157 | — |
| Oregon Health & Science University /ID# 1128-0251 | Portland | Oregon | 97239-3011 | — |
| Penn State Hershey Medical Ctr /ID# 1128-0220 | Hershey | Pennsylvania | 17033-2360 | — |
| Abramson Cancer Center of the Univ. of Pennsylvania /ID# 1128-0402 | Philadelphia | Pennsylvania | 19104 | — |
| Vanderbilt Infectious Disease Clinic /ID# 1128-0024 | Nashville | Tennessee | 37232 | — |
| The University of Texas Medical Branch (UTMB) - Cancer Center - Galves /ID# 1128-0974 | Galveston | Texas | 77555-0565 | — |
| Duplicate_Scott & White Mem Hosp & Clin /ID# 1128-0046 | Temple | Texas | 76508 | — |
| Duplicate_Virginia Cancer Specialists - Fairfax Office /ID# 1128-0972 | Fairfax | Virginia | 22031 | — |
| Virginia Mason Medical Center /ID# 1128-0005 | Seattle | Washington | 98101 | — |
| University of Washington /ID# 1128-1382 | Seattle | Washington | 98109 | — |
| Confluence Health /ID# 1128-0894 | Wenatchee | Washington | 98801 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 21 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02599324, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 17, 2023 · Synced Sep 29, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02599324 live on ClinicalTrials.gov.