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Completed No phase listed Observational

Tracking Outcomes and Practice in Pediatric Pulmonary Hypertension

ClinicalTrials.gov ID: NCT02610660

Public ClinicalTrials.gov record NCT02610660. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 23, 2026, 9:23 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The TOPP-2 registry is an international, non-interventional, prospective registry including children and adolescents newly diagnosed with pulmonary hypertension (PH) to gain further insights in the disease course and long-term outcome of PH in childhood. Patients will undergo clinical assessments and receive standard medical care, as determined by treating physicians in their daily clinical practice. The TOPP-2 registry is specifically designed to capture the variables that have been proposed as treatment goals in PePH and the reasons for changes in treatment strategy. The TOPP-2 registry uses the new clinical classification of PH as outlined at the 5th World Symposium for Pulmonary Hypertension (WSPH) in Nice 2013 and includes new characterizations for children with PH. The registry is planned and implemented under the scientific leadership of the Association for Pediatric Pulmonary Hypertension (PePH), independently from the financial sponsors. All enrolled patients will have a follow-up period of 18 months.

Study identification

NCT ID
NCT02610660
Recruitment status
Completed
Study type
Observational
Phase
Not listed
Enrollment
388 participants

Conditions and interventions

Interventions

Not listed

Eligibility (public fields only)

Age range
3 Months to 18 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 31, 2015
Primary completion
Dec 30, 2022
Completion
Dec 30, 2022
Last update posted
Apr 12, 2023

2015 – 2022

United States locations

U.S. sites
13
U.S. states
13
U.S. cities
13
Facility City State ZIP Site status
Stanford Children's Hospital Palo Alto California 94304
University of Colorado Denver School of Medicine, Children's Hospital Colorado Aurora Colorado 80045
Children's National Medical Center Washington D.C. District of Columbia 20010
Emory University Atlanta Georgia 30322
Boston Children's Hospital Boston Massachusetts 02115
St Louis Children's Hospital St Louis Missouri 63110
University of Nebraska Medical Center Omaha Nebraska 68198
Columbia University Medical Center New York New York 10032
Cincinnati Children's Hospital Medical Center Cincinnati Ohio 45229
Vanderbilt University Children's Hospital Nashville Tennessee 37232-9310
Texas Children's Hospital Houston Texas 77030
Primary Children's Hospital Salt Lake City Utah 84113
Seattle Children's Hospital Seattle Washington 98105

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 19 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02610660, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 12, 2023 · Synced Sep 23, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02610660 live on ClinicalTrials.gov.

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