ClinicalTrials.gov record
Ublituximab + TGR-1202 Compared to Obinutuzumab + Chlorambucil in Participants With Untreated and Previously Treated Chronic Lymphocytic Leukemia
ClinicalTrials.gov ID: NCT02612311
Public ClinicalTrials.gov record NCT02612311. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 3, Randomized Study to Assess the Efficacy and Safety of Ublituximab in Combination With TGR-1202 (Umbralisib) Compared to Obinutuzumab in Combination With Chlorambucil in Patients With Chronic Lymphocytic Leukemia (CLL)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study evaluates the combination of ublituximab, a novel monoclonal antibody, and TGR-1202, a novel PI3K delta inhibitor compared to obinutuzumab and chlorambucil, and compared to ublituximab or TGR-1202 alone in Chronic Lymphocytic Leukemia (CLL) participants.
Study identification
- NCT ID
- NCT02612311
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 603 participants
Conditions and interventions
Conditions
Interventions
- Obinutuzumab Biological
- Ublituximab Biological
- TGR-1202 Drug
- Chlorambucil Drug
Biological · Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 19, 2015 (Actual)
- Primary completion
- Feb 22, 2023 (Actual)
- Completion
- Feb 22, 2023 (Actual)
- Last update posted
- Dec 13, 2024
2015 – 2023
United States locations
- U.S. sites
- 110
- U.S. states
- 37
- U.S. cities
- 103
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| TG Therapeutics Investigational Trial Site | Huntsville | Alabama | 35805 | — |
| TG Therapeutics Investigational Trial Site | Mobile | Alabama | 36604 | — |
| TG Therapeutics Investigational Trial Site | Chandler | Arizona | 85224 | — |
| TG Therapeutics Investigational Trial Site | Phoenix | Arizona | 85016 | — |
| TG Therapeutics Investigational Trial Site | Tucson | Arizona | 85711 | — |
| TG Therapeutics Investigational Trial Site | Fayetteville | Arkansas | 72703 | — |
| TG Therapeutics Investigational Trial Site | Concord | California | 94520 | — |
| TG Therapeutics Investigational Trial Site | Duarte | California | 91010 | — |
| TG Therapeutics Investigational Trial Site | Greenbrae | California | 94904 | — |
| TG Therapeutics Investigational Trial Site | Pismo Beach | California | 93449 | — |
| TG Therapeutics Investigational Trial Site | Pleasanton | California | 94588 | — |
| TG Therapeutics Investigational Trial Site | San Diego | California | 92120 | — |
| TG Therapeutics Investigational Trial Site | Santa Barbara | California | 93105 | — |
| TG Therapeutics Investigational Trial Site | Whittier | California | 90603 | — |
| TG Therapeutics Investigational Trial Site | Aurora | Colorado | 80012 | — |
| TG Therapeutics Investigational Trial Site | Denver | Colorado | 80218 | — |
| TG Therapeutics Investigational Trial Site | Bridgeport | Connecticut | 06606 | — |
| TG Therapeutics Investigational Trial Site | New Haven | Connecticut | 06519 | — |
| TG Therapeutics Investigational Trial Site | Stamford | Connecticut | 06904 | — |
| TG Therapeutics Investigational Trial Site | Newark | Delaware | 19713 | — |
| TG Therapeutics Investigational Trial Site | Boca Raton | Florida | 33486 | — |
| TG Therapeutics Investigational Trial Site | Fort Myers | Florida | 33916 | — |
| TG Therapeutics Investigational Trial Site | Jacksonville | Florida | 32204 | — |
| TG Therapeutics Investigational Trial Site | Jacksonville | Florida | 32256 | — |
| TG Therapeutics Investigational Trial Site | Ocala | Florida | 34471 | — |
| TG Therapeutics Investigational Trial Site | Pensacola | Florida | 32504 | — |
| TG Therapeutics Investigational Trial Site | St. Petersburg | Florida | 33705 | — |
| TG Therapeutics Investigational Trial Site | Tallahassee | Florida | 32308 | — |
| TG Therapeutics Investigational Trial Site | Tampa | Florida | 33612 | — |
| TG Therapeutics Investigational Trial Site | West Palm Beach | Florida | 33407 | — |
| TG Therapeutics Investigational Trial Site | Albany | Georgia | 31701 | — |
| TG Therapeutics Investigational Trial Site | Macon | Georgia | 31201 | — |
| TG Therapeutics Investigational Trial Site | Chicago | Illinois | 60612 | — |
| TG Therapeutics Investigational Trial Site | Decatur | Illinois | 62526 | — |
| TG Therapeutics Investigational Trial Site | Maywood | Illinois | 60153 | — |
| TG Therapeutics Investigational Trial Site | Niles | Illinois | 60714 | — |
| TG Therapeutics Investigational Trial Site | Peoria | Illinois | 61615 | — |
| TG Therapeutics Investigational Trial Site | Swansea | Illinois | — | — |
| TG Therapeutics Investigational Trial Site | Urbana | Illinois | 61801 | — |
| TG Therapeutics Investigational Trial Site | Fort Wayne | Indiana | 46804 | — |
| TG Therapeutics Investigational Trial Site | Indianapolis | Indiana | 46237 | — |
| TG Therapeutics Investigational Trial Site | Ames | Iowa | 50010 | — |
| TG Therapeutics Investigational Trial Site | Cedar Rapids | Iowa | 52403 | — |
| TG Therapeutics Investigational Trial Site | Kansas City | Kansas | 64132 | — |
| TG Therapeutics Investigational Trial Site | Westwood | Kansas | 66210 | — |
| TG Therapeutics Investigational Trial Site | Louisville | Kentucky | 40207 | — |
| TG Therapeutics Investigational Trial Site | Baltimore | Maryland | 21202 | — |
| TG Therapeutics Investigational Trial Site | Baltimore | Maryland | 21215 | — |
| TG Therapeutics Investigational Trial Site | Bethesda | Maryland | 20817 | — |
| TG Therapeutics Investigational Trial Site | Columbia | Maryland | 21044 | — |
| TG Therapeutics Investigational Trial Site | Boston | Massachusetts | 02111 | — |
| TG Therapeutics Investigational Trial Site | Worcester | Massachusetts | 01608 | — |
| TG Therapeutics Investigational Trial Site | Ann Arbor | Michigan | 48106 | — |
| TG Therapeutics Investigational Trial Site | Detroit | Michigan | 48202 | — |
| TG Therapeutics Investigational Trial Site | Jackson | Michigan | 49201 | — |
| TG Therapeutics Investigational Trial Site | Saint Louis Park | Minnesota | 55416 | — |
| TG Therapeutics Investigational Trial Site | Columbia | Missouri | 65212 | — |
| TG Therapeutics Investigational Trial Site | Kansas City | Missouri | — | — |
| TG Therapeutics Investigational Trial Site | Lincoln | Nebraska | 68510 | — |
| TG Therapeutics Investigational Trial Site | Las Vegas | Nevada | 89119 | — |
| TG Therapeutics Investigational Trial Site | Lebanon | New Hampshire | 03756 | — |
| TG Therapeutics Investigational Trial Site | Morristown | New Jersey | 07962 | — |
| TG Therapeutics Investigational Trial Site | Somerville | New Jersey | 00876 | — |
| TG Therapeutics Investigational Trial Site | East Setauket | New York | 11733 | — |
| TG Therapeutics Investigational Trial Site | Glens Falls | New York | 12801 | — |
| TG Therapeutics Investigational Trial Site | Syracuse | New York | 13210 | — |
| TG Therapeutics Investigational Trial Site | Charlotte | North Carolina | 28204 | — |
| TG Therapeutics Investigational Trial Site | Durham | North Carolina | 27710 | — |
| TG Therapeutics Investigational Trial Site | Durham | North Carolina | — | — |
| TG Therapeutics Investigational Trial Site | Hickory | North Carolina | 28602 | — |
| TG Therapeutics Investigational Trial Site | Kinston | North Carolina | 28501 | — |
| TG Therapeutics Investigational Trial Site | Raleigh | North Carolina | 27607 | — |
| TG Therapeutics Investigational Trial Site | Washington | North Carolina | 27889 | — |
| TG Therapeutics Investigational Trial Site | Canton | Ohio | 44718 | — |
| TG Therapeutics Investigational Trial Site | Cincinnati | Ohio | 45236 | — |
| TG Therapeutics Investigational Trial Site | Toledo | Ohio | 43623 | — |
| TG Therapeutics Investigational Trial Site | Portland | Oregon | 97227 | — |
| TG Therapeutics Investigational Trial Site | Portland | Oregon | 97239 | — |
| TG Therapeutics Investigational Trial Site | Springfield | Oregon | 97477 | — |
| TG Therapeutics Investigational Trial Site | Camp Hill | Pennsylvania | 17011 | — |
| TG Therapeutics Investigational Trial Site | Danville | Pennsylvania | 17822 | — |
| TG Therapeutics Investigational Trial Site | Hershey | Pennsylvania | 17033 | — |
| TG Therapeutics Investigational Trial Site | Philadelphia | Pennsylvania | 19106 | — |
| TG Therapeutics Investigational Trial Site | Pittsburgh | Pennsylvania | 15224 | — |
| TG Therapeutics Investigational Trial Site | Pittsburgh | Pennsylvania | 15232 | — |
| TG Therapeutics Investigational Trial Site | Pawtucket | Rhode Island | 00286 | — |
| TG Therapeutics Investigational Trial Site | Greenville | South Carolina | 29615 | — |
| TG Therapeutics Investigational Trial Site | Sioux Falls | South Dakota | 57105 | — |
| TG Therapeutics Investigational Trial Site | Watertown | South Dakota | 57201 | — |
| TG Therapeutics Investigational Trial Site | Chattanooga | Tennessee | 37404 | — |
| TG Therapeutics Investigational Trial Site | Nashville | Tennessee | 37203 | — |
| TG Therapeutics Investigational Trial Site | Austin | Texas | 78705 | — |
| TG Therapeutics Investigational Trial Site | Bedford | Texas | 76022 | — |
| TG Therapeutics Investigational Trial Site | Fort Worth | Texas | 76104 | — |
| TG Therapeutics Investigational Trial Site | Houston | Texas | 77030 | — |
| TG Therapeutics Investigational Trial Site | San Antonio | Texas | 78217 | — |
| TG Therapeutics Investigational Trial Site | San Antonio | Texas | 78229 | — |
| TG Therapeutics Investigational Trial Site | Tyler | Texas | 75702 | — |
| TG Therapeutics Investigational Trial Site | Ogden | Utah | 84405 | — |
| TG Therapeutics Investigational Trial Site | Blacksburg | Virginia | 24060 | — |
| TG Therapeutics Investigational Trial Site | Charlottesville | Virginia | 22908 | — |
| TG Therapeutics Investigational Trial Site | Fort Belvoir | Virginia | 22060 | — |
| TG Therapeutics Investigational Trial Site | Olympia | Washington | 98502 | — |
| TG Therapeutics Investigational Trial Site | Seattle | Washington | 98104 | — |
| TG Therapeutics Investigational Trial Site | Seattle | Washington | 98109 | — |
| TG Therapeutics Investigational Trial Site | Spokane | Washington | 99216 | — |
| TG Therapeutics Investigational Trial Site | Vancouver | Washington | 98684 | — |
| TG Therapeutics Investigational Trial Site | Yakima | Washington | 98902 | — |
| TG Therapeutics Investigational Trial Site | Milwaukee | Wisconsin | 53226 | — |
| TG Therapeutics Investigational Trial Site | Wauwatosa | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 44 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02612311, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 13, 2024 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02612311 live on ClinicalTrials.gov.