Safety and Efficacy of Piromelatine in Mild Alzheimer's Disease Patients (ReCOGNITION)
Public ClinicalTrials.gov record NCT02615002. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Randomized, Double-blind, Parallel-group, Placebo-controlled, Dose Ranging Study of Piromelatine in Patients With Mild Dementia Due to Alzheimer's Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is a Phase 2, randomized, placebo-controlled, dose-ranging study of piromelatine (5, 20, and 50 mg daily for 6 months) versus placebo to determine an effective dose based on efficacy (cognitive performance), safety, and tolerability in patients with mild dementia due to Alzheimer's Disease (AD).
Study identification
- NCT ID
- NCT02615002
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 371 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 60 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 2015 (Type not available)
- Primary completion
- Jun 2019 (Actual)
- Completion
- Nov 19, 2019 (Actual)
- Last update posted
- Jul 5, 2024
2015 – 2019
United States locations
- U.S. sites
- 56
- U.S. states
- 22
- U.S. cities
- 50
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | — |
| Territory Neurology & Research Institute | Tucson | Arizona | 85704 | — |
| Citrials Inc | Bellflower | California | 90706 | — |
| Alliance for Research | Long Beach | California | 90807 | — |
| Renew Behavioral Health, Inc | Long Beach | California | 90807 | — |
| ABS Health LLC | Pomona | California | 91767 | — |
| Anderson Clinical Research | Redlands | California | 92374 | — |
| Pacific Research Network, Inc | San Diego | California | 92103 | — |
| Sharp Mesa Vista Clinical research | San Diego | California | 92123 | — |
| Syrentis Clinical Research | Santa Ana | California | 92705 | — |
| Research Center For Clinical Studies, Inc | Norwalk | Connecticut | 06851 | — |
| Pioneer Clinical research | Coconut Creek | Florida | 33066 | — |
| University of Miami | Coral Gables | Florida | 33146 | — |
| MD Clinical | Hallandale | Florida | 33009 | — |
| New Life Medical Research Center | Hialeah | Florida | 33012 | — |
| Galiz reserach | Hialeah | Florida | 33016 | — |
| Biomed Research Institute | Miami | Florida | 33126 | — |
| Miami Jewish Health Systems | Miami | Florida | 33137 | — |
| Advanced Clinical research Network | Miami | Florida | 33176 | — |
| Medical Research Group of central Florida Inc. | Orange City | Florida | 32763 | — |
| The Roskamp Institute, Inc | Sarasota | Florida | 34243 | — |
| Infinity Clinical Research, LLC. | Sunrise | Florida | 33351 | — |
| Olympian Clinical Research | Tampa | Florida | 33609 | — |
| Rowe Neurology | Lenexa | Kansas | 66214 | — |
| KU School of Medicine-Wichita | Wichita | Kansas | 67214 | — |
| Lake Charles Clinical Trials, LLC | Lake Charles | Louisiana | 27604 | — |
| Pharmasite Research INC | Baltimore | Maryland | 21208 | — |
| Quest Research Institute | Farmington Hills | Michigan | 48334 | — |
| Precise Research Centers | Flowood | Mississippi | 39232 | — |
| Hattiesburg Clinic, P.A. | Hattiesburg | Mississippi | 39401 | — |
| Galen Research | Chesterfield | Missouri | 63005 | — |
| The Neurocognitive Institute, LLC | Mount Arlington | New Jersey | 07856 | — |
| Alzheimer's Research Corporation | Paterson | New Jersey | 08759 | — |
| Global Medical Institutes | Princeton | New Jersey | 08540 | — |
| Neurology Specialists of Monmouth County | West Long Branch | New Jersey | 07764 | — |
| Dent Neurosciences Research Center, Inc | Amherst | New York | 14226 | — |
| Integrative Clinical Trials, LLC | Brooklyn | New York | 11229 | — |
| SPRI Clinical Trials, LLC | Brooklyn | New York | 11235 | — |
| Manhattan Behavioral Medicine, PLLC | New York | New York | 10022 | — |
| Richmond Behavioral Associates | Staten Island | New York | 10312 | — |
| SUNY Upstate Medical University | Syracuse | New York | 13210 | — |
| New Hope Clinical research | Charlotte | North Carolina | 28211 | — |
| Richard H. Weisler, M.D., P.A. & Associates | Raleigh | North Carolina | 27609 | — |
| The Ohio State University | Columbus | Ohio | 43221 | — |
| Red river medical research Center | Oklahoma City | Oklahoma | 73112 | — |
| Tulsa Clinical Research, LLC. | Tulsa | Oklahoma | 74104 | — |
| The Clinical research Center LLC | Jenkintown | Pennsylvania | 19046 | — |
| Suburban Research Associates | Media | Pennsylvania | 19063 | — |
| Roper St. Francis Healthcare | Charleston | South Carolina | 29401 | — |
| Shepherd Clinical Research LLC | Lewisville | Texas | 75067 | — |
| Radiant Research | San Antonio | Texas | 78229 | — |
| Grayline Research Center | Wichita Falls | Texas | 76309 | — |
| Aspen Clinical research | Orem | Utah | 84058 | — |
| Wasatch Clinical Research LLC | Salt Lake City | Utah | 84107 | — |
| Zain Research, Llc | Richland | Washington | 99352 | — |
| SSM Health/Dean Medical Group | Madison | Wisconsin | 53715 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02615002, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 5, 2024 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02615002 live on ClinicalTrials.gov.