A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Prophylactic Emicizumab Versus no Prophylaxis in Hemophilia A Participants With Inhibitors
Public ClinicalTrials.gov record NCT02622321. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Multicenter, Open-Label, Phase III Clinical Trial to Evaluate the Efficacy, Safety, and Pharmacokinetics of Prophylactic Emicizumab Versus no Prophylaxis in Hemophilia A Patients With Inhibitors
Study identification
- NCT ID
- NCT02622321
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Hoffmann-La Roche
- Industry
- Enrollment
- 113 participants
Conditions and interventions
Conditions
Interventions
- Emicizumab Drug
- rFVIIa Drug
- aPCC Drug
Drug
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 17, 2015
- Primary completion
- Oct 24, 2016
- Completion
- Nov 30, 2020
- Last update posted
- Jun 23, 2021
2015 – 2020
United States locations
- U.S. sites
- 11
- U.S. states
- 10
- U.S. cities
- 11
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Children's Hospital Los Angeles | Los Angeles | California | 90010 | — |
| Santa Monica Oncology Center | Santa Monica | California | 90403 | — |
| University of Colorado Denver, Children's Hospital | Aurora | Colorado | 80045 | — |
| Winship Cancer Institute | Atlanta | Georgia | 30322 | — |
| Boston Childrens Hospital | Boston | Massachusetts | 02115 | — |
| Children's Hospital of Michigan; Pediatrics | Detroit | Michigan | 48201 | — |
| Cornell Univ Medical College; Hematology-Oncolog | New York | New York | 10021 | — |
| Oregon Health & Science Uni ; Dept of Pediatrics | Portland | Oregon | 97201 | — |
| Pennsylvania State Hershey Medical Center; Division of Hematology/Oncology, H046 | Hershey | Pennsylvania | 17033-0850 | — |
| Univ of TX Health Science Ctr; Gulf States Hemo and Throm Ctr | Houston | Texas | 77030 | — |
| Bloodworks Northwest (formerly Puget Sound Blood Center); Hemophilia | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 33 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02622321, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 23, 2021 · Synced Jul 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02622321 live on ClinicalTrials.gov.