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Completed Phase 1Phase 2 Interventional

Study Evaluating Brexucabtagene Autoleucel (KTE-X19) in Pediatric and Adolescent Participants With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia or Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma

ClinicalTrials.gov ID: NCT02625480

Public ClinicalTrials.gov record NCT02625480. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 20, 2026, 2:38 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1/2 Multi-Center Study Evaluating the Safety and Efficacy of KTE-X19 in Pediatric and Adolescent Subjects With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia or Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma (ZUMA-4)

Study identification

NCT ID
NCT02625480
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Kite, A Gilead Company
Industry
Enrollment
95 participants

Conditions and interventions

Interventions

  • Brexucabtagene Autoleucel (KTE-X19) Biological
  • Cyclophosphamide Drug
  • Fludarabine Drug

Biological · Drug

Eligibility (public fields only)

Age range
Up to 21 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 31, 2016
Primary completion
Mar 24, 2026
Completion
Mar 24, 2026
Last update posted
Apr 8, 2026

2016 – 2026

United States locations

U.S. sites
15
U.S. states
11
U.S. cities
14
Facility City State ZIP Site status
Children's Hospital Los Angeles Los Angeles California 90027
Children's Hospital of Orange County Orange California 92868
UCSF Benioff Children's Hospital San Francisco California 94158
University of Miami Hospital & Clinics Miami Florida 33136
Kapi'olani Medical Center for Women and Children Honolulu Hawaii 96826
Ann & Robert H. Lurie Children's Hospital Chicago Illinois 60611
Johns Hopkins University Baltimore Maryland 21287
Children's Hospitals and Clinics of Minnesota Minneapolis Minnesota 55404
Columbia University Irving Medical Center/Morgan Stanley Children's Hospital-NYP New York New York 10032
University of Rochester Medical Center Rochester New York 14642
The Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104
Monroe-Carell Jr. Children's Hospital at Vanderbilt Nashville Tennessee 37232
Texas Children's Hospital Houston Texas 77030
The University of Texas M.D. Anderson Cancer Center Houston Texas 77030
University of Virginia Health System, Pediatric Hematology/Oncology Clinic Charlottesville Virginia 22908

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 15 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02625480, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 8, 2026 · Synced May 20, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02625480 live on ClinicalTrials.gov.

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