Baroreflex Activation Therapy for Heart Failure
Public ClinicalTrials.gov record NCT02627196. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Barostim Neo® - Baroreflex Activation Therapy® for Heart Failure
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this clinical trial (NCT02627196) is to develop valid scientific evidence for safety and effectiveness of Baroreflex Activation Therapy with the BAROSTIM NEO System in subjects with heart failure, defined as New York Heart Association (NYHA) functional Class III, left ventricular ejection fraction (LVEF) ≤ 35% and NT-proBNP\<1600 pg/ml despite being treated with the appropriate heart failure guideline directed therapy, excluding subjects eligible for or actively receiving Cardiac Resynchronization Therapy (CRT). The total trial duration is anticipated to be approximately 5 years; however, the duration of an individual subject enrollment will depend on when he or she entered the trial.
Study identification
- NCT ID
- NCT02627196
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 1,090 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 21 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 19, 2016 (Actual)
- Primary completion
- Oct 2023 (Actual)
- Completion
- Oct 2023 (Actual)
- Last update posted
- Mar 10, 2026
2016 – 2023
United States locations
- U.S. sites
- 88
- U.S. states
- 31
- U.S. cities
- 77
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Heart and Rhythm Solutions, PLLC | Chandler | Arizona | 85286 | — |
| Chan Heart Rhythm Institute | Mesa | Arizona | 85206 | — |
| Arizona Arrhythmia Research Center | Phoenix | Arizona | 85016 | — |
| Phoenix Cardiovascular Research Group | Phoenix | Arizona | 85018 | — |
| Cardiovascular Consultants, Ltd. | Phoenix | Arizona | 85032 | — |
| Washington Regional Medical Center | Fayetteville | Arkansas | 72703 | — |
| Central Cardiology Medical Center | Bakersfield | California | 93308 | — |
| Chula Vista Cardiac Center | Chula Vista | California | 91910 | — |
| Sharp Grossmont | Chula Vista | California | 91911 | — |
| Sharp Chula Vista Medical Center | Chula Vista | California | 91991 | — |
| John Muir Health Clinical Research Center | Concord | California | 94520 | — |
| University of California, San Francisco - Fresno | Fresno | California | 93701 | — |
| Herndon Surgery Center | Fresno | California | 93720 | — |
| Glendale Adventist Medical Center | Glendale | California | 91204 | — |
| Memorial Health Services | Laguna Hills | California | 92653 | — |
| Los Alamitos Cardiovascular | Los Alamitos | California | 90720 | — |
| Southern California Permanente Medical Group | Los Angeles | California | 90027 | — |
| University of Southern California | Los Angeles | California | 90033 | — |
| Advanced Cardiovascular Specialists | Mountain View | California | 94040 | — |
| Hoag Memorial Hospital | Newport Beach | California | 92663 | — |
| UC Irvine Health | Orange | California | 92868 | — |
| Desert Heart Regional Medical Center | Palm Springs | California | 92262 | — |
| Huntington Hospital | Pasadena | California | 91105 | — |
| Dignity Health | Sacramento | California | 95819 | — |
| University of California San Francisco | San Francisco | California | 94143 | — |
| Bonometti, Inc | Santa Barbara | California | 93101 | — |
| Adventist Heart Institute | St. Helena | California | 94574 | — |
| North Colorado Medical Center | Greeley | Colorado | 80631 | — |
| Medical Center of the Rockies Research | Loveland | Colorado | 80538 | — |
| Atlantic Clinical Research Center - Cardiology | Atlantis | Florida | 33462 | — |
| Clearwater Cardiovascular Consultants | Clearwater | Florida | 33756 | — |
| Holy Cross Hospital | Fort Lauderdale | Florida | 33308 | — |
| Memorial Cardiovascular Institute | Hollywood | Florida | 33021 | — |
| AdventHealth Orlando | Orlando | Florida | 32803 | — |
| Avanza Medical Research Center | Pensacola | Florida | 32503 | — |
| University of South Florida | Tampa | Florida | 33606 | — |
| Mercer University | Macon | Georgia | 31201 | — |
| WellStar Medical Group | Marietta | Georgia | 30060 | — |
| St. Alphonsus Medical Center | Boise | Idaho | 83704 | — |
| NorthShore University Health System | Evanston | Illinois | 60201 | — |
| Advocate Medical Group | Naperville | Illinois | 60540 | — |
| Prairie Education and Research Cooperative | Springfield | Illinois | 62701 | — |
| University of Kansas Medical Center Research Institute, Inc. | Kansas City | Kansas | 66160 | — |
| Via Christi Research | Wichita | Kansas | 67214 | — |
| Baptist Health Lexington | Lexington | Kentucky | 40503 | — |
| University of Kentucky | Lexington | Kentucky | 40536 | — |
| Cardiovascular Institute of the South | Houma | Louisiana | 70360 | — |
| Tulane University & Vascular Institute | New Orleans | Louisiana | 70112 | — |
| Ochsner Clinic Foundation | New Orleans | Louisiana | 70121 | — |
| St. Elizabeth's Medical Center | Brighton | Massachusetts | 02135 | — |
| Detroit Medical Center Cardiovascular Institute | Detroit | Michigan | 48201 | — |
| Ascension St. Mary's Research Institute | Saginaw | Michigan | 48602 | — |
| Providence-Providence Park Hospital | Southfield | Michigan | 48075 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| Mercy Hospital Springfield | Springfield | Missouri | 65804 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| St. Louis Heart and Vascular | St Louis | Missouri | 63136 | — |
| Mercy Hospital St. Louis | St Louis | Missouri | 63141 | — |
| Nebraska Heart Institute | Lincoln | Nebraska | 68526 | — |
| University Medical Center of Southern Nevada | Las Vegas | Nevada | 89102 | — |
| Healthcare Partners Clinical Research | Las Vegas | Nevada | 89169 | — |
| Deborah Heart and Lung Center | Browns Mills | New Jersey | 08015 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Presbyterian Heart Group | Albuquerque | New Mexico | 87106 | — |
| University of Rochester | Rochester | New York | 14642 | — |
| St. Francis Hospital - Long Island | Roslyn | New York | 11576 | — |
| Cone Health | Greensboro | North Carolina | 27401 | — |
| WakeMed | Raleigh | North Carolina | 27610 | — |
| Wake Forest Baptist Health | Winston-Salem | North Carolina | 27157 | — |
| The Christ Hospital | Cincinnati | Ohio | 45219 | — |
| Ohio State University | Columbus | Ohio | 43210 | — |
| Oklahoma Cardiovascular Research Group | Oklahoma City | Oklahoma | 73120 | — |
| Oregon Health & Science University | Portland | Oregon | 97239 | — |
| Drexel University | Philadelphia | Pennsylvania | 19102 | — |
| Allegheny-Singer Research Institute | Pittsburgh | Pennsylvania | 15212 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| McLeod Cardiology Associates | Florence | South Carolina | 29506 | — |
| Stern Cardiovascular Foundation | Germantown | Tennessee | 38138 | — |
| Texas Cardiac Arrhythmia Research Foundation | Austin | Texas | 78705 | — |
| Cardiovascular Research Institute of Dallas | Dallas | Texas | 75231 | — |
| Private Practice Leadership | Houston | Texas | 77094 | — |
| Methodist Richardson Medical Center | Richardson | Texas | 75082 | — |
| Tyler Cardiovascular Consultants | Tyler | Texas | 75701 | — |
| Intermountain Heart Institute | Murray | Utah | 84107 | — |
| University of Utah | Salt Lake City | Utah | 84132 | — |
| Virginia Mason Medical Center | Seattle | Washington | 98101 | — |
| CHI Franciscan Health Research Center | Tacoma | Washington | 98405 | — |
| Columbia St. Mary's Hospital | Milwaukee | Wisconsin | 53211 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02627196, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 10, 2026 · Synced Oct 18, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02627196 live on ClinicalTrials.gov.