An Open Label Extension Study to Evaluate Inhaled Treprostinil in Adult PH With ILD Including CPFE
Public ClinicalTrials.gov record NCT02633293. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-Label Extension Study of Inhaled Treprostinil in Subjects With Pulmonary Hypertension Due to Parenchymal Lung Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a multicenter, open-label trial to evaluate the safety and efficacy of inhaled treprostinil in subjects with pre-capillary pulmonary hypertension (PH) associated with interstitial lung disease (ILD) including combined pulmonary fibrosis and emphysema (CPFE). The study will include about 266 patients who completed all required assessments in the RIN-PH-201 study at approximately 100 clinical trial centers. The study will continue Your participation in this study is voluntary and will last until you discontinue from the study or the study ends. The study will continue until each subject reaches the Week 108 visit or until inhaled treprostinil become commercially available for patients with PH associated with ILD including CPFE (whichever is sooner).
Study identification
- NCT ID
- NCT02633293
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 243 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 15, 2016 (Actual)
- Primary completion
- Aug 1, 2021 (Actual)
- Completion
- Aug 1, 2021 (Actual)
- Last update posted
- Dec 2, 2022
2016 – 2021
United States locations
- U.S. sites
- 91
- U.S. states
- 33
- U.S. cities
- 70
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| IMC-Diagnostic & Medical Clinic | Mobile | Alabama | 36604 | — |
| Arizona Pulmonary Specialists, Ltd. | Phoenix | Arizona | 85012 | — |
| University of Arizona | Tucson | Arizona | 85724 | — |
| Cedars-Sinai Medical Center | Beverly Hills | California | 90211 | — |
| University of California, San Francisco-Fresno | Fresno | California | 93701 | — |
| University of California San Diego | La Jolla | California | 92093 | — |
| VA Long Beach Healthcare System | Long Beach | California | 90822 | — |
| University of Southern California | Los Angeles | California | 90033 | — |
| Department of Veterans Affairs Greater Los Angeles Healthcare System | Los Angeles | California | 90073 | — |
| Pacific Pulmonary Medical Group | Riverside | California | 92505 | — |
| University of California Davis Medical Center | Sacramento | California | 95817 | — |
| Kaiser Permanente | San Francisco | California | 94115 | — |
| University of Colorado Hospital - Cardiac and Vascular Center | Aurora | Colorado | 80045 | — |
| National Jewish Health | Denver | Colorado | 80206 | — |
| Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | — |
| MedStar Heart & Vascular Institute | Washington D.C. | District of Columbia | 20010 | — |
| Florida Lung, Asthma & Sleep Specialists, P.A. | Celebration | Florida | 34747 | — |
| St. Francis Sleep, Allergy and Lung Institute | Clearwater | Florida | 33765 | — |
| University of Florida Clinical Research Center | Gainesville | Florida | 32610 | — |
| University of Florida College of Medicine, Jacksonville | Jacksonville | Florida | 32209 | — |
| Mayo Clinic Jacksonville | Jacksonville | Florida | 32224 | — |
| St. Vincent's Lung, Sleep, and Critical Care Specialists | Jacksonville | Florida | 33204 | — |
| University of Miami | Miami | Florida | 33136 | — |
| Florida Hospital | Orlando | Florida | 32804 | — |
| University of South Florida | Tampa | Florida | 33606 | — |
| Cleveland Clinic Florida | Weston | Florida | 33331 | — |
| The Emory Clinic | Atlanta | Georgia | 30322 | — |
| Piedmont - Georgia Lung Associates | Austell | Georgia | 30106 | — |
| Wellstar Medical Group | Marietta | Georgia | 30060 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| University of Illinois at Chicago Hospital | Chicago | Illinois | 60612 | — |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| Indiana University Hospital | Indianapolis | Indiana | 46202 | — |
| Community Heart and Vascular Hospital | Indianapolis | Indiana | 46250 | — |
| St. Vincent Medical Group, Inc. | Indianapolis | Indiana | 46260 | — |
| University of Iowa Hospitals & Clinics | Iowa City | Iowa | 52242 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| University of Louisville Physicians Outpatient Center | Louisville | Kentucky | 40202 | — |
| Louisiana State University Health Sciences Center New Orleans | New Orleans | Louisiana | 70112 | — |
| Maine Medical Center | South Portland | Maine | 04106 | — |
| University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| Johns Hopkins University | Baltimore | Maryland | 21205 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Spectrum Health Medical Center | Grand Rapids | Michigan | 49503 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| Saint Luke's Hospital of Kansas City | Kansas City | Missouri | 64111 | — |
| Washington University Hospital | St Louis | Missouri | 63110 | — |
| The University of New Mexico | Albuquerque | New Mexico | 87131 | — |
| Albany Medical College | Albany | New York | 12208 | — |
| New York Methodist Hospital | Brooklyn | New York | 11215 | — |
| Northwell Health | New Hyde Park | New York | 11040 | — |
| NYU Langone Medical Center | New York | New York | 10016 | — |
| The Mount Sinai Hospital | New York | New York | 10029 | — |
| Weill Cornell Medical Center | New York | New York | 10065 | — |
| University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27599 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Pinehurst Medical Clinic, Inc. | Pinehurst | North Carolina | 28374 | — |
| The Carl and Edyth Lindner Research Center at The Christ Hospital | Cincinnati | Ohio | 45219 | — |
| University of Cincinnati Health | Cincinnati | Ohio | 45267 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| The Ohio State University Medical Center | Columbus | Ohio | 43221 | — |
| Integris Baptist Medical Center | Oklahoma City | Oklahoma | 73112 | — |
| Hospital of University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| AnMed Health Pulmonary and Sleep Medicine | Anderson | South Carolina | 29621 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Statcare Pulmonary Consultants | Knoxville | Tennessee | 37919 | — |
| Baylor University Medical Center at Dallas | Dallas | Texas | 75246 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Texas Tech University Health Sciences Center | El Paso | Texas | 79905 | — |
| Houston Methodist | Houston | Texas | 77030 | — |
| Michael E. DeBakey VA Medical Center | Houston | Texas | 77030 | — |
| The University of Texas Health Science Center at Houston | Houston | Texas | 77030 | — |
| The University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | — |
| University of Vermont, Vermont Lung Center | Colchester | Vermont | 05446 | — |
| Inova Fairfax Hospital | Fairfax | Virginia | 22042 | — |
| Sentara Cardiovascular Research Institute | Norfolk | Virginia | 23507 | — |
| Pulmonary Associates of Richmond | Richmond | Virginia | 23229 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
| University of Wisconsin School of Medicine and Public Health | Madison | Wisconsin | 53792 | — |
| Aurora St. Luke's Medical Center | Milwaukee | Wisconsin | 53215 | — |
| Medical College of Wisconsin/Froedtert Hospital | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02633293, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 2, 2022 · Synced Oct 25, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02633293 live on ClinicalTrials.gov.