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Completed Phase 2 Interventional Results available

A Trial of IW-3718 for 8 Weeks in Patients With Symptomatic Gastroesophageal Reflux Disease (GERD)

ClinicalTrials.gov ID: NCT02637557

Public ClinicalTrials.gov record NCT02637557. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 20, 2026, 9:25 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2b, Randomized, Double-blind, Placebo-controlled, Parallel-group, Dose-range-finding Trial of IW-3718 Administered Orally for 8 Weeks to Patients With Symptomatic Gastroesophageal Reflux Disease Not Completely Responsive to Proton Pump Inhibitors

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The objectives of this study are to evaluate the safety, efficacy, and dose-response relationship of IW-3718 administered orally to participants who have GERD and continue to experience GERD symptoms while receiving once-daily (QD), standard-dose proton pump inhibitors (PPIs).

Study identification

NCT ID
NCT02637557
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Ironwood Pharmaceuticals, Inc.
Industry
Enrollment
282 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 1, 2016 (Actual)
Primary completion
Apr 26, 2017 (Actual)
Completion
Apr 26, 2017 (Actual)
Last update posted
Oct 15, 2019

2016 – 2017

United States locations

U.S. sites
62
U.S. states
24
U.S. cities
57
Facility City State ZIP Site status
IW-3718 Investigator Dothan Alabama 36305 —
IW-3718 Investigator Phoenix Arizona 85018 —
IW-3718 Investigator Tucson Arizona 85710 —
IW-3718 Investigator Tucson Arizona 85712 —
IW-3718 Investigator Tucson Arizona 85741 —
IW-3718 Investigator North Little Rock Arkansas 72117 —
IW-3718 Investigator Anaheim California 92801 —
IW-3718 Investigator Carmichael California 95608 —
IW-3718 Investigator Chula Vista California 91910 —
IW-3718 Investigator La Mirada California 90638 —
IW-3718 Investigator Mission Hills California 91345 —
IW-3718 Investigator Newport Beach California 92660 —
IW-3718 Investigator Oakland California 94612 —
IW-3718 Investigator Sacramento California 95821 —
IW-3718 Investigator San Diego California 92123 —
IW-3718 Investigator Bristol Connecticut 06010 —
IW-3718 Investigator Waterbury Connecticut 06708 —
IW-3718 Investigator DeLand Florida 32720 —
IW-3718 Investigator Hollywood Florida 33024 —
IW-3718 Investigator Inverness Florida 34452 —
IW-3718 Investigator Jupiter Florida 33458 —
IW-3718 Investigator Lauderdale Lakes Florida 33319 —
IW-3718 Investigator Miami Florida 33126 —
IW-3718 Investigator Miami Florida 33135 —
IW-3718 Investigator Miami Lakes Florida 33014 —
IW-3718 Investigator Port Orange Florida 32129 —
IW-3718 Investigator Clive Iowa 50325 —
IW-3718 Investigator Bowling Green Kentucky 42101 —
IW-3718 Investigator Monroe Louisiana 71201 —
IW-3718 Investigator Annapolis Maryland 21401 —
IW-3718 Investigator Baltimore Maryland 21215 —
IW-3718 Investigator Chevy Chase Maryland 20815 —
IW-3718 Investigator Chesterfield Michigan 48047 —
IW-3718 Investigator Wyoming Michigan 49519 —
IW-3718 Investigator Las Vegas Nevada 89128 —
IW-3718 Investigator Reno Nevada 89511 —
IW-3718 Investigator Egg Harbor New Jersey 08234 —
IW-3718 Investigator Great Neck New York 11021 —
IW-3718 Investigator Great Neck New York 11023 —
IW-3718 Investigator Kew Gardens New York 11415 —
IW-3718 Investigator New York New York 10065 —
IW-3718 Investigator Asheville North Carolina 28801 —
IW-3718 Investigator Raleigh North Carolina 27612 —
IW-3718 Investigator Fargo North Dakota 58103 —
IW-3718 Investigator Cleveland Ohio 44109 —
IW-3718 Investigator Columbus Ohio 43213 —
IW-3718 Investigator Lima Ohio 45806 —
IW-3718 Investigator Norman Oklahoma 73071 —
IW-3718 Investigator Oklahoma City Oklahoma 73104 —
IW-3718 Investigator Pittsburgh Pennsylvania 15243 —
IW-3718 Investigator Charleston South Carolina 29412 —
IW-3718 Investigator Chattanooga Tennessee 37421 —
IW-3718 Investigator Germantown Tennessee 38138 —
IW-3718 Investigator Nashville Tennessee 37232 —
IW-3718 Investigator El Paso Texas 79905 —
IW-3718 Investigator Houston Texas 77098 —
IW-3718 Investigator San Antonio Texas 78209 —
IW-3718 Investigator San Antonio Texas 78229 —
IW-3718 Investigator Sandy City Utah 84092 —
IW-3718 Investigator South Ogden Utah 84405 —
IW-3718 Investigator Christiansburg Virginia 24073 —
IW-3718 Investigator Lynchburg Virginia 24502 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02637557, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 15, 2019 · Synced Oct 20, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02637557 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →