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Completed Phase 2 Interventional Results available

A Trial of IW-3718 for 8 Weeks in Patients With Symptomatic Gastroesophageal Reflux Disease (GERD)

ClinicalTrials.gov ID: NCT02637557

Public ClinicalTrials.gov record NCT02637557. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 5, 2026, 4:43 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2b, Randomized, Double-blind, Placebo-controlled, Parallel-group, Dose-range-finding Trial of IW-3718 Administered Orally for 8 Weeks to Patients With Symptomatic Gastroesophageal Reflux Disease Not Completely Responsive to Proton Pump Inhibitors

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The objectives of this study are to evaluate the safety, efficacy, and dose-response relationship of IW-3718 administered orally to participants who have GERD and continue to experience GERD symptoms while receiving once-daily (QD), standard-dose proton pump inhibitors (PPIs).

Study identification

NCT ID
NCT02637557
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Ironwood Pharmaceuticals, Inc.
Industry
Enrollment
282 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 29, 2016
Primary completion
Apr 25, 2017
Completion
Apr 25, 2017
Last update posted
Oct 14, 2019

2016 – 2017

United States locations

U.S. sites
62
U.S. states
24
U.S. cities
57
Facility City State ZIP Site status
IW-3718 Investigator Dothan Alabama 36305
IW-3718 Investigator Phoenix Arizona 85018
IW-3718 Investigator Tucson Arizona 85710
IW-3718 Investigator Tucson Arizona 85712
IW-3718 Investigator Tucson Arizona 85741
IW-3718 Investigator North Little Rock Arkansas 72117
IW-3718 Investigator Anaheim California 92801
IW-3718 Investigator Carmichael California 95608
IW-3718 Investigator Chula Vista California 91910
IW-3718 Investigator La Mirada California 90638
IW-3718 Investigator Mission Hills California 91345
IW-3718 Investigator Newport Beach California 92660
IW-3718 Investigator Oakland California 94612
IW-3718 Investigator Sacramento California 95821
IW-3718 Investigator San Diego California 92123
IW-3718 Investigator Bristol Connecticut 06010
IW-3718 Investigator Waterbury Connecticut 06708
IW-3718 Investigator DeLand Florida 32720
IW-3718 Investigator Hollywood Florida 33024
IW-3718 Investigator Inverness Florida 34452
IW-3718 Investigator Jupiter Florida 33458
IW-3718 Investigator Lauderdale Lakes Florida 33319
IW-3718 Investigator Miami Florida 33126
IW-3718 Investigator Miami Florida 33135
IW-3718 Investigator Miami Lakes Florida 33014
IW-3718 Investigator Port Orange Florida 32129
IW-3718 Investigator Clive Iowa 50325
IW-3718 Investigator Bowling Green Kentucky 42101
IW-3718 Investigator Monroe Louisiana 71201
IW-3718 Investigator Annapolis Maryland 21401
IW-3718 Investigator Baltimore Maryland 21215
IW-3718 Investigator Chevy Chase Maryland 20815
IW-3718 Investigator Chesterfield Michigan 48047
IW-3718 Investigator Wyoming Michigan 49519
IW-3718 Investigator Las Vegas Nevada 89128
IW-3718 Investigator Reno Nevada 89511
IW-3718 Investigator Egg Harbor New Jersey 08234
IW-3718 Investigator Great Neck New York 11021
IW-3718 Investigator Great Neck New York 11023
IW-3718 Investigator Kew Gardens New York 11415
IW-3718 Investigator New York New York 10065
IW-3718 Investigator Asheville North Carolina 28801
IW-3718 Investigator Raleigh North Carolina 27612
IW-3718 Investigator Fargo North Dakota 58103
IW-3718 Investigator Cleveland Ohio 44109
IW-3718 Investigator Columbus Ohio 43213
IW-3718 Investigator Lima Ohio 45806
IW-3718 Investigator Norman Oklahoma 73071
IW-3718 Investigator Oklahoma City Oklahoma 73104
IW-3718 Investigator Pittsburgh Pennsylvania 15243
IW-3718 Investigator Charleston South Carolina 29412
IW-3718 Investigator Chattanooga Tennessee 37421
IW-3718 Investigator Germantown Tennessee 38138
IW-3718 Investigator Nashville Tennessee 37232
IW-3718 Investigator El Paso Texas 79905
IW-3718 Investigator Houston Texas 77098
IW-3718 Investigator San Antonio Texas 78209
IW-3718 Investigator San Antonio Texas 78229
IW-3718 Investigator Sandy City Utah 84092
IW-3718 Investigator South Ogden Utah 84405
IW-3718 Investigator Christiansburg Virginia 24073
IW-3718 Investigator Lynchburg Virginia 24502

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02637557, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 14, 2019 · Synced Sep 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02637557 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →