Naltrexone/Bupropion Cardiovascular Outcomes Study
Public ClinicalTrials.gov record NCT02638129. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 4 Study to Assess the Effect of Naltrexone Hydrochloride and Bupropion Hydrochloride Extended Release Combination on the Occurrence of Major Adverse Cardiovascular Events in Overweight and Obese Subjects With Cardiovascular Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate cardiovascular (CV) safety of naltrexone hydrochloride (HCl) and bupropion HCl extended release combination (NB) compared with placebo and rule out excess risk of major adverse cardiovascular events (MACE) when given in combination with standard of care in overweight and obese participants with documented history of CV disease.
Study identification
- NCT ID
- NCT02638129
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 67 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 2016 (Type not available)
- Primary completion
- Jun 2016 (Actual)
- Completion
- Jun 2016 (Actual)
- Last update posted
- Feb 27, 2017
2016
United States locations
- U.S. sites
- 139
- U.S. states
- 36
- U.S. cities
- 139
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Alexander City | Alabama | — | — |
| Not listed | Auburn | Alabama | — | — |
| Not listed | Birmingham | Alabama | — | — |
| Not listed | Huntsville | Alabama | — | — |
| Not listed | Campe Verde | Arizona | — | — |
| Not listed | Chandler | Arizona | — | — |
| Not listed | Cottonwood | Arizona | — | — |
| Not listed | Fountain Hills | Arizona | — | — |
| Not listed | Mesa | Arizona | — | — |
| Not listed | Phoenix | Arizona | — | — |
| Not listed | Tucson | Arizona | — | — |
| Not listed | Fayetteville | Arkansas | — | — |
| Not listed | Jonesboro | Arkansas | — | — |
| Not listed | Little Rock | Arkansas | — | — |
| Not listed | Arvin | California | — | — |
| Not listed | Bakersfield | California | — | — |
| Not listed | Chino | California | — | — |
| Not listed | Downey | California | — | — |
| Not listed | El Cajon | California | — | — |
| Not listed | Los Alamitos | California | — | — |
| Not listed | Los Angeles | California | — | — |
| Not listed | Pomona | California | — | — |
| Not listed | Sacramento | California | — | — |
| Not listed | Santa Ana | California | — | — |
| Not listed | Santa Monica | California | — | — |
| Not listed | Denver | Colorado | — | — |
| Not listed | New London | Connecticut | — | — |
| Not listed | Stamford | Connecticut | — | — |
| Not listed | Trumbull | Connecticut | — | — |
| Not listed | Waterbury | Connecticut | — | — |
| Not listed | Wilmington | Delaware | — | — |
| Not listed | Boca Raton | Florida | — | — |
| Not listed | Bradenton | Florida | — | — |
| Not listed | Brandon | Florida | — | — |
| Not listed | Brooksville | Florida | — | — |
| Not listed | Coral Springs | Florida | — | — |
| Not listed | Cutler Bay | Florida | — | — |
| Not listed | Daytona Beach | Florida | — | — |
| Not listed | Hialeah | Florida | — | — |
| Not listed | Inverness | Florida | — | — |
| Not listed | Jacksonville Beach | Florida | — | — |
| Not listed | Lake Worth | Florida | — | — |
| Not listed | Largo | Florida | — | — |
| Not listed | Miami Lakes | Florida | — | — |
| Not listed | Orlando | Florida | — | — |
| Not listed | Palm Harbor | Florida | — | — |
| Not listed | Pembroke Pines | Florida | — | — |
| Not listed | Ponte Vedra Beach | Florida | — | — |
| Not listed | Sarasota | Florida | — | — |
| Not listed | Stuart | Florida | — | — |
| Not listed | Atlanta | Georgia | — | — |
| Not listed | Duluth | Georgia | — | — |
| Not listed | Savannah | Georgia | — | — |
| Not listed | Honolulu | Hawaii | — | — |
| Not listed | Pocatello | Idaho | — | — |
| Not listed | Blue Island | Illinois | — | — |
| Not listed | Chicago | Illinois | — | — |
| Not listed | Evanston | Illinois | — | — |
| Not listed | Gurnee | Illinois | — | — |
| Not listed | Rock Island | Illinois | — | — |
| Not listed | Evansville | Indiana | — | — |
| Not listed | Topeka | Kansas | — | — |
| Not listed | Louisville | Kentucky | — | — |
| Not listed | Owensboro | Kentucky | — | — |
| Not listed | Baton Rouge | Louisiana | — | — |
| Not listed | Bossier City | Louisiana | — | — |
| Not listed | Lake Charles | Louisiana | — | — |
| Not listed | Shreveport | Louisiana | — | — |
| Not listed | Baltimore | Maryland | — | — |
| Not listed | Catonsville | Maryland | — | — |
| Not listed | Bay City | Michigan | — | — |
| Not listed | Saginaw | Michigan | — | — |
| Not listed | Port Gibson | Mississippi | — | — |
| Not listed | Hazelwood | Missouri | — | — |
| Not listed | Great Falls | Montana | — | — |
| Not listed | Las Vegas | Nevada | — | — |
| Not listed | Linden | New Jersey | — | — |
| Not listed | Moorestown | New Jersey | — | — |
| Not listed | Albuquerque | New Mexico | — | — |
| Not listed | Endwell | New York | — | — |
| Not listed | Great Neck | New York | — | — |
| Not listed | Mineola | New York | — | — |
| Not listed | New York | New York | — | — |
| Not listed | Saratoga Springs | New York | — | — |
| Not listed | Staten Island | New York | — | — |
| Not listed | Asheville | North Carolina | — | — |
| Not listed | Cary | North Carolina | — | — |
| Not listed | Charlotte | North Carolina | — | — |
| Not listed | Durham | North Carolina | — | — |
| Not listed | Greenville | North Carolina | — | — |
| Not listed | Hickory | North Carolina | — | — |
| Not listed | Morehead City | North Carolina | — | — |
| Not listed | Raleigh | North Carolina | — | — |
| Not listed | Rocky Mount | North Carolina | — | — |
| Not listed | Salisbury | North Carolina | — | — |
| Not listed | Winston-Salem | North Carolina | — | — |
| Not listed | Canton | Ohio | — | — |
| Not listed | Cincinnati | Ohio | — | — |
| Not listed | Cleveland | Ohio | — | — |
| Not listed | Columbus | Ohio | — | — |
| Not listed | Perrysburg | Ohio | — | — |
| Not listed | Sandusky | Ohio | — | — |
| Not listed | Willoughby | Ohio | — | — |
| Not listed | Altoona | Pennsylvania | — | — |
| Not listed | Camp Hill | Pennsylvania | — | — |
| Not listed | Doylestown | Pennsylvania | — | — |
| Not listed | Lansdale | Pennsylvania | — | — |
| Not listed | Pittsburgh | Pennsylvania | — | — |
| Not listed | Smithfield | Pennsylvania | — | — |
| Not listed | Yardley | Pennsylvania | — | — |
| Not listed | Charleston | South Carolina | — | — |
| Not listed | Moncks Corner | South Carolina | — | — |
| Not listed | Mt. Pleasant | South Carolina | — | — |
| Not listed | Simpsonville | South Carolina | — | — |
| Not listed | Bristol | Tennessee | — | — |
| Not listed | Jackson | Tennessee | — | — |
| Not listed | Knoxville | Tennessee | — | — |
| Not listed | Memphis | Tennessee | — | — |
| Not listed | Arlington | Texas | — | — |
| Not listed | Dallas | Texas | — | — |
| Not listed | Houston | Texas | — | — |
| Not listed | Katy | Texas | — | — |
| Not listed | Kingwood | Texas | — | — |
| Not listed | Palestine | Texas | — | — |
| Not listed | Plano | Texas | — | — |
| Not listed | San Antonio | Texas | — | — |
| Not listed | Bountiful | Utah | — | — |
| Not listed | Murray | Utah | — | — |
| Not listed | Ogden | Utah | — | — |
| Not listed | Orem | Utah | — | — |
| Not listed | South Ogden | Utah | — | — |
| Not listed | West Jordan | Utah | — | — |
| Not listed | West | Utah | — | — |
| Not listed | Richmond | Virginia | — | — |
| Not listed | Roanoke | Virginia | — | — |
| Not listed | Virginia Beach | Virginia | — | — |
| Not listed | Port Orchard | Washington | — | — |
| Not listed | Charleston | West Virginia | — | — |
| Not listed | Kenosha | Wisconsin | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02638129, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 27, 2017 · Synced Oct 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02638129 live on ClinicalTrials.gov.