Efficacy and Safety Study of BMS-986142 in Patients With Moderate to Severe Rheumatoid Arthritis
Public ClinicalTrials.gov record NCT02638948. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 2, Randomized, Multi-Center, Double-Blind, Dose-Ranging, Placebo Controlled, Adaptive Design Study to Evaluate the Efficacy and Safety/Pharmacokinetics of BMS-986142 in Subjects With Moderate to Severe Rheumatoid Arthritis With an Inadequate Response to Methotrexate With or Without TNF Inhibitors
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine whether the study drug, BMS-986142, is safe and effective in treating moderate to severe rheumatoid arthritis in subjects with an inadequate response to methotrexate or methotrexate and up to 2 tumour necrosis factor (TNF) Inhibitors. Patients who qualify will be randomized to either one of 3 doses of BMS-986142 or placebo in 1:1:1 randomization for 12 weeks. Disease activity and safety will be assessed over the course of the study.
Study identification
- NCT ID
- NCT02638948
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 508 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 120 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 16, 2016 (Actual)
- Primary completion
- May 3, 2018 (Actual)
- Completion
- May 3, 2018 (Actual)
- Last update posted
- May 28, 2019
2016 – 2018
United States locations
- U.S. sites
- 26
- U.S. states
- 12
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Rheumatology Associates Of North Alabama, P.C. | Huntsville | Alabama | 35801 | — |
| St. Joseph Heritage Medical Group | Fullerton | California | 92835 | — |
| C.V Mehta M.D Medical Corp | Hemet | California | 92543 | — |
| HCP Clinical Research, LLC | Huntington Beach | California | 92646 | — |
| Leon Medical Research | Miami | Florida | 33015 | — |
| San Marcus Research Clinic, Inc. | Miami | Florida | 33015 | — |
| Coral Research Clinic Corp | Miami | Florida | 33175 | — |
| Precision Research Organization | Miami Lakes | Florida | 33016 | — |
| The Arthritis Center | Palm Harbor | Florida | 34684 | — |
| Vizae Clinical Trials Management | Pembroke Pines | Florida | 33026 | — |
| Integral Rheumatology & Immunology Specialists | Plantation | Florida | 33324 | — |
| North Georgia Rheumatology Group | Lawrenceville | Georgia | 30046 | — |
| Arthritis And Diabetes Clinic | Monroe | Louisiana | 71203 | — |
| Clinical Pharmacology Study Group | Worcester | Massachusetts | 01605 | — |
| Aa Mrc Llc | Grand Blanc | Michigan | 48439 | — |
| Albuquerque Center For Rheumatology | Albuquerque | New Mexico | 87102 | — |
| Albuquerque Clinical Trials | Albuquerque | New Mexico | 87102 | — |
| Paramount Medical Research & Consulting, Llc | Middleburg Heights | Ohio | 44130 | — |
| East Penn Rheumatology | Bethlehem | Pennsylvania | 18015 | — |
| Altoona Center For Clinical Research | Duncansville | Pennsylvania | 16635-8406 | — |
| Advanced Rheumatology & Arthritis Research Center, P.C | Wexford | Pennsylvania | 15090 | — |
| Local Institution | Wyomissing | Pennsylvania | 19610 | — |
| West Tennessee Research Institute | Jackson | Tennessee | 38305 | — |
| Pharma Tex Research | Amarillo | Texas | 79106 | — |
| Tekton Research Inc | Austin | Texas | 78745 | — |
| Southwest Rheumatology Research LLC | Mesquite | Texas | 75150 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 78 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02638948, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 28, 2019 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02638948 live on ClinicalTrials.gov.