Study of Urate Elevation in Parkinson's Disease, Phase 3
Public ClinicalTrials.gov record NCT02642393. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled Trial of Urate-elevating Inosine Treatment to Slow Clinical Decline in Early Parkinson's Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A multicenter, randomized, double-blind, placebo-controlled, phase 3 trial to determine whether oral inosine dosed to moderately elevate serum urate (from ≤5.7 mg/dL to 7.1-8.0 mg/dL) over 2 years slows clinical decline in early PD. Clinical decline will be assessed as change in the primary outcome variable of the Movement Disorders Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS), a composite scale comprising patient- and clinician-reported outcomes.
Study identification
- NCT ID
- NCT02642393
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 298 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 30 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2016 (Actual)
- Primary completion
- Jun 2019 (Actual)
- Completion
- Jun 2019 (Actual)
- Last update posted
- Jul 28, 2020
2016 – 2019
United States locations
- U.S. sites
- 61
- U.S. states
- 32
- U.S. cities
- 54
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | — |
| Barrow Neurological Institute | Phoenix | Arizona | 85013 | — |
| Mayo Clinic Arizona | Scottsdale | Arizona | 85259 | — |
| Banner Sun Health Research Institute | Sun City | Arizona | 85351 | — |
| University of California San Diego | La Jolla | California | 92093 | — |
| University of Southern California | Los Angeles | California | 90033 | — |
| University of California Davis | Sacramento | California | 95817 | — |
| University of California San Francisco | San Francisco | California | 94143 | — |
| University of Colorado | Aurora | Colorado | 80045 | — |
| Rocky Mountain Movement Disorder Center | Englewood | Colorado | 80113 | — |
| Hartford HealthCare Movement Disorders Center | Vernon | Connecticut | 06066 | — |
| University of South Florida | Tampa | Florida | 33613 | — |
| Emory University | Atlanta | Georgia | 30329 | — |
| Augusta University | Augusta | Georgia | 30912 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Neurosciences Institute at Central DuPage Hospital | Winfield | Illinois | 60190 | — |
| Indiana University | Indianapolis | Indiana | 46202 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| University of Louisville | Louisville | Kentucky | 40202 | — |
| Oschner Clinic Foundation | New Orleans | Louisiana | 70121 | — |
| University of Maryland, Baltimore | Baltimore | Maryland | 21201 | — |
| Johns Hopkins University | Baltimore | Maryland | 21287 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Boston University Medical Center | Boston | Massachusetts | 02118 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| University of Michigan | Ann Arbor | Michigan | 48105 | — |
| Michigan State University | East Lansing | Michigan | 48824 | — |
| Henry Ford Health System | West Bloomfield | Michigan | 48322 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| Cleveland Clinic Lou Ruvo Center for Brain Health | Las Vegas | Nevada | 89106 | — |
| Overlook Medical Center, Atlantic Neuroscience Institute | Summit | New Jersey | 07901 | — |
| Albany Medical College | Albany | New York | 12208 | — |
| SUNY Downstate Medical Center | Brooklyn | New York | 11203 | — |
| Weill Cornell Medical Center | New York | New York | 10021 | — |
| SUNY Upstate Medical University | Syracuse | New York | 13210 | — |
| Duke University | Durham | North Carolina | 27705 | — |
| University of Cincinnati/Cincinnati Children's Hospital | Cincinnati | Ohio | 45219 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Ohio State University | Columbus | Ohio | 43221 | — |
| Oregon Health & Sciences University | Portland | Oregon | 97239 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19107 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | — |
| Butler Hospital | Providence | Rhode Island | 02906 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29403 | — |
| Wesley Neurology Clinic, PC | Cordova | Tennessee | 38018 | — |
| University of Tennessee Health Science Center | Memphis | Tennessee | 38163 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390-9036 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| University of Texas Houston Medical School | Houston | Texas | 77030 | — |
| Baylor Scott & White Health | Temple | Texas | 76508 | — |
| The University of Vermont | Burlington | Vermont | 05405 | — |
| University of Virginia | Charlottesville | Virginia | 22908 | — |
| VCU Parkinson's & Movement Disorder Center (McGuire Veterans Hospital) | Richmond | Virginia | 23230 | — |
| Sentara Neurology Specialists | Virginia Beach | Virginia | 23456 | — |
| Inland Northwest Research | Spokane | Washington | 99202 | — |
| Northwest Neurological PLLC | Spokane | Washington | 99202 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02642393, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 28, 2020 · Synced Oct 31, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02642393 live on ClinicalTrials.gov.