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Completed Phase 1 Interventional

A Study of Oral Vismodegib in Combination With Pirfenidone in Participants With Idiopathic Pulmonary Fibrosis

ClinicalTrials.gov ID: NCT02648048

Public ClinicalTrials.gov record NCT02648048. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 26, 2026, 12:21 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Single Arm, Multicenter, Open-label, Phase 1b Study to Assess the Safety and Tolerability of Oral Vismodegib in Combination With Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis

Study identification

NCT ID
NCT02648048
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
21 participants

Conditions and interventions

Interventions

  • Pirfenidone Drug
  • Vismodegib Drug

Drug

Eligibility (public fields only)

Age range
40 Years to 80 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 14, 2016
Primary completion
Nov 29, 2016
Completion
Nov 29, 2016
Last update posted
Oct 29, 2017

2016

United States locations

U.S. sites
14
U.S. states
12
U.S. cities
14
Facility City State ZIP Site status
Scripps Clinic La Jolla California 92037
Central Florida Pulmonary Group, PA Orlando Florida 32803
Suburban Lung Associates Elk Grove Illinois 60007
Medical Consultants, PC ; Pulmonary Muncie Indiana 47303
University of Louisville Louisville Kentucky 40202-1798
Tulane University Medical School New Orleans Louisiana 70112
Steward St. Elizabeth's Medical Center ; Pulmonary, Critical Care and Sleep Medicine Boston Massachusetts 02135
Creighton University Medical Center Omaha Nebraska 68131
Allied Clinical Research Reno Nevada 89503
Atlantic Respiratory Institute Summit New Jersey 07901
Pulmonix LLC Greensboro North Carolina 27403
PMG Research of Wilmington Wilmington North Carolina 28401
Western Washington Medical Group Everett Washington 98208
Swedish Medical Center Seattle Washington 98122

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02648048, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 29, 2017 · Synced Jun 26, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02648048 live on ClinicalTrials.gov.

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