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Completed Phase 1Phase 2 Interventional Results available

Sym015 (Anti-MET) in Patients With Advanced Solid Tumor Malignancies

ClinicalTrials.gov ID: NCT02648724

Public ClinicalTrials.gov record NCT02648724. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 20, 2026, 8:41 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-Label, Multicenter Phase 1a/2a Trial Investigating the Safety, Tolerability and Antitumor Activity of Multiple Doses of Sym015, a Monoclonal Antibody Mixture Targeting MET, in Patients With Advanced Solid Tumor Malignancies

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is the first study to test Sym015 in humans. The primary purpose of this study is to see if Sym015 is safe and effective for patients with advanced solid tumor malignancies without available therapeutic options.

Study identification

NCT ID
NCT02648724
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Symphogen A/S
Industry
Enrollment
57 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 2016 (Actual)
Primary completion
Dec 2020 (Actual)
Completion
Dec 2020 (Actual)
Last update posted
Jun 22, 2022

2016 – 2020

United States locations

U.S. sites
10
U.S. states
7
U.S. cities
9
Facility City State ZIP Site status
University of Colorado Cancer Center Aurora Colorado 80045 —
University of Chicago Medical Center Chicago Illinois 60637 —
Indiana University Health Melvin and Bren Simon Cancer Center Indianapolis Indiana 46202 —
Massachusetts General Hospital Boston Massachusetts 02114 —
Dana Farber Cancer Institute/D -1251 Boston Massachusetts 02215 —
Comprehensive Cancer Centers of Nevada Las Vegas Nevada 89169 —
University Hospitals Cleveland Medical Center Cleveland Ohio 44106 —
University of Texas Southwestern Medical Center Dallas Texas 75390 —
The University of Texas M.D. Anderson Cancer Center Houston Texas 77030 —
South Texas Accelerated Research Therapeutics, LLC San Antonio Texas 78229 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 17 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02648724, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 22, 2022 · Synced Oct 20, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02648724 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →