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Terminated Phase 1 Interventional

Extension Study of BIIB092 in Participants With Progressive Supranuclear Palsy (PSP) Who Participated in CN002003

ClinicalTrials.gov ID: NCT02658916

Public ClinicalTrials.gov record NCT02658916. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 5, 2026, 12:37 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Open-Label, Long-Term Treatment Study of Intravenously Administered BIIB092 in Patients With Progressive Supranuclear Palsy Who Participated in Study CN002003

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the long-term safety and tolerability of multiple intravenous (IV) infusions of BIIB092 in participants with Progressive Supranuclear Palsy (PSP). The study will also assess the pharmacodynamic (PD) effects of BIIB092 on cerebrospinal fluid (CSF) N-terminal tau, pharmacokinetics (PK), and immunogenicity of BIIB092 in participants with PSP.

Study identification

NCT ID
NCT02658916
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1
Lead sponsor
Biogen
Industry
Enrollment
47 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
41 Years to 86 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 21, 2016
Primary completion
Mar 30, 2020
Completion
Mar 30, 2020
Last update posted
May 17, 2020

2016 – 2020

United States locations

U.S. sites
13
U.S. states
9
U.S. cities
13
Facility City State ZIP Site status
The University of Alabama at Birmingham Birmingham Alabama 35294
University of California San Diego La Jolla California 92037
David Geffen School of Medicine at UCLA Los Angeles California 90024
University of California, San Francisco, Medical Center at Parnassus San Francisco California 94158
Parkinson's Disease and Movement Disorders Center of Boca Raton, Inc. Boca Raton Florida 33486
University of Florida College of Medicine Gainesville Florida 32607
University of South Florida Tampa Florida 33612
The University of Chicago Medical Center Chicago Illinois 60637
University of Minnesota Medical School Minneapolis Minnesota 55455-0341
Robert Wood Johnson Medical School New Brunswick New Jersey 08901-1962
Columbia University Medical Center New York New York 10032
Hospital of the University of Pennsylvania Philadelphia Pennsylvania 19104-4206
The University of Texas Southwestern Medical Center Dallas Texas 75390-8830

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02658916, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 17, 2020 · Synced Sep 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02658916 live on ClinicalTrials.gov.

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