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Completed Phase 2 Interventional Results available

Study of Poziotinib in Participants With HER2-Positive Metastatic Breast Cancer

ClinicalTrials.gov ID: NCT02659514

Public ClinicalTrials.gov record NCT02659514. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 23, 2026, 1:47 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Study of Poziotinib in Patients With HER2-Positive Metastatic Breast Cancer (MBC) Who Have Received Prior HER2 Regimens for MBC

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to establish the dose regimen and evaluate the preliminary efficacy and the safety/tolerability of poziotinib in participants with human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer who have received at least two prior HER2-directed treatment regimens.

Study identification

NCT ID
NCT02659514
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Spectrum Pharmaceuticals, Inc
Industry
Enrollment
67 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 90 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 22, 2016 (Actual)
Primary completion
Mar 11, 2020 (Actual)
Completion
Mar 11, 2020 (Actual)
Last update posted
Mar 11, 2022

2016 – 2020

United States locations

U.S. sites
35
U.S. states
18
U.S. cities
34
Facility City State ZIP Site status
Clearview Cancer Center Huntsville Alabama 35805 —
Pacific Cancer Medical Center, Inc. Anaheim California 92801 —
Marin Cancer Care, Inc Greenbrae California 94904 —
Alliance Research Centers Laguna Hills California 92653 —
PacificShores Medical Group Long Beach California 90813 —
Valley Medical Oncology Consultants Pleasanton California 94588 —
Innovative Clinical Research Institute Whittier California 90603 —
AMPM Research Clinic Miami Gardens Florida 33169 —
FL Cancer Research Institute Plantation Florida 33324 —
Bond Clinic, P.A. Winter Haven Florida 33880 —
Triple Army Medical Cente Honolulu Hawaii 96859 —
Franciscan St. Francis Health Indianapolis Indiana 46237 —
The University of Kansas Cancer Center and Medical Pavilion Westwood Kansas 66205 —
Hattiesburg Clinic Hematology Oncology Hattiesburg Mississippi 39401 —
Washington University St Louis Missouri 63110 —
St. Vincent Frontier Cancer Center Billings Montana 59102 —
North Shore Hematology Oncology Associates East Setauket New York 11733 —
Hudson Valley Hematology Oncology Associates Poughkeepsie New York 12601 —
White Plain Hospital White Plains New York 10601 —
Waverly Hematology Oncology Cary North Carolina 27518 —
Aultman Hospital Canton Ohio 44710 —
Ohio State University Columbus Ohio 43210 —
Oklahoma Cancer Specialists & Research Institute, LLC Tulsa Oklahoma 74146 —
Magee Womens Hospital of UPMC Pittsburgh Pennsylvania 15213 —
Charleston Cancer Center Charleston South Carolina 29406 —
Carolina Blood and Cancer Care Associates PA Rock Hill South Carolina 29732 —
Oncology Consultants, P.A. Houston Texas 77030 —
SAMMC - Hem/Onc Clinic Houston Texas 78234 —
Texas Oncology-McAllen McAllen Texas 78503 —
The University of Texas Health Science Center at San Antonio San Antonio Texas 78229 —
Scott & White Memorial Hospital Temple Texas 76508 —
Providence Regional Cancer System Lacey Washington 98503 —
Medical Oncology Associates, PS Spokane Washington 99208 —
Northwest Medical Specialties, PLLC Tacoma Washington 98405 —
West Virginia University Morgantown West Virginia 26506 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02659514, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 11, 2022 · Synced Oct 23, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02659514 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →