Study of Poziotinib in Participants With HER2-Positive Metastatic Breast Cancer
Public ClinicalTrials.gov record NCT02659514. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Study of Poziotinib in Patients With HER2-Positive Metastatic Breast Cancer (MBC) Who Have Received Prior HER2 Regimens for MBC
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to establish the dose regimen and evaluate the preliminary efficacy and the safety/tolerability of poziotinib in participants with human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer who have received at least two prior HER2-directed treatment regimens.
Study identification
- NCT ID
- NCT02659514
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 67 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 90 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 21, 2016
- Primary completion
- Mar 10, 2020
- Completion
- Mar 10, 2020
- Last update posted
- Mar 10, 2022
2016 – 2020
United States locations
- U.S. sites
- 35
- U.S. states
- 18
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clearview Cancer Center | Huntsville | Alabama | 35805 | — |
| Pacific Cancer Medical Center, Inc. | Anaheim | California | 92801 | — |
| Marin Cancer Care, Inc | Greenbrae | California | 94904 | — |
| Alliance Research Centers | Laguna Hills | California | 92653 | — |
| PacificShores Medical Group | Long Beach | California | 90813 | — |
| Valley Medical Oncology Consultants | Pleasanton | California | 94588 | — |
| Innovative Clinical Research Institute | Whittier | California | 90603 | — |
| AMPM Research Clinic | Miami Gardens | Florida | 33169 | — |
| FL Cancer Research Institute | Plantation | Florida | 33324 | — |
| Bond Clinic, P.A. | Winter Haven | Florida | 33880 | — |
| Triple Army Medical Cente | Honolulu | Hawaii | 96859 | — |
| Franciscan St. Francis Health | Indianapolis | Indiana | 46237 | — |
| The University of Kansas Cancer Center and Medical Pavilion | Westwood | Kansas | 66205 | — |
| Hattiesburg Clinic Hematology Oncology | Hattiesburg | Mississippi | 39401 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| St. Vincent Frontier Cancer Center | Billings | Montana | 59102 | — |
| North Shore Hematology Oncology Associates | East Setauket | New York | 11733 | — |
| Hudson Valley Hematology Oncology Associates | Poughkeepsie | New York | 12601 | — |
| White Plain Hospital | White Plains | New York | 10601 | — |
| Waverly Hematology Oncology | Cary | North Carolina | 27518 | — |
| Aultman Hospital | Canton | Ohio | 44710 | — |
| Ohio State University | Columbus | Ohio | 43210 | — |
| Oklahoma Cancer Specialists & Research Institute, LLC | Tulsa | Oklahoma | 74146 | — |
| Magee Womens Hospital of UPMC | Pittsburgh | Pennsylvania | 15213 | — |
| Charleston Cancer Center | Charleston | South Carolina | 29406 | — |
| Carolina Blood and Cancer Care Associates PA | Rock Hill | South Carolina | 29732 | — |
| Oncology Consultants, P.A. | Houston | Texas | 77030 | — |
| SAMMC - Hem/Onc Clinic | Houston | Texas | 78234 | — |
| Texas Oncology-McAllen | McAllen | Texas | 78503 | — |
| The University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | — |
| Scott & White Memorial Hospital | Temple | Texas | 76508 | — |
| Providence Regional Cancer System | Lacey | Washington | 98503 | — |
| Medical Oncology Associates, PS | Spokane | Washington | 99208 | — |
| Northwest Medical Specialties, PLLC | Tacoma | Washington | 98405 | — |
| West Virginia University | Morgantown | West Virginia | 26506 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02659514, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 10, 2022 · Synced Sep 3, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02659514 live on ClinicalTrials.gov.