Transcatheter Aortic Valve Replacement to UNload the Left Ventricle in Patients With ADvanced Heart Failure (TAVR UNLOAD)
Public ClinicalTrials.gov record NCT02661451. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Transcatheter Aortic Valve Replacement to UNload the Left Ventricle in Patients With ADvanced Heart Failure: A Randomized Trial (TAVR UNLOAD)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objective of this study is to determine the safety and efficacy of transcatheter aortic valve replacement (TAVR) via a transfemoral approach in HF patients with moderate AS as compared with OHFT.
Study identification
- NCT ID
- NCT02661451
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 178 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 2016 (Actual)
- Primary completion
- Feb 28, 2023 (Actual)
- Completion
- Feb 2025 (Estimated)
- Last update posted
- Nov 27, 2024
2016 – 2025
United States locations
- U.S. sites
- 46
- U.S. states
- 25
- U.S. cities
- 40
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Chandler Regional Medical Center | Chandler | Arizona | 85224 | — |
| UCSD/Sulpizio Cardiovascular Center | La Jolla | California | 92037 | — |
| University of Southern California - Los Angeles | Los Angeles | California | 90033 | — |
| UCLA Medical Center | Los Angeles | California | 90095 | — |
| St. Joseph Hospital | Orange | California | 92868 | — |
| UCSF | San Francisco | California | 94143 | — |
| Medical Center of the Rockies | Loveland | Colorado | 80538 | — |
| Yale University | New Haven | Connecticut | 06520 | — |
| Medstar Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | — |
| University of Miami | Miami | Florida | 33136 | — |
| Cleveland Clinic Florida | Weston | Florida | 33331 | — |
| Advocate Christ Hospital | Chicago | Illinois | 60453 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Alexian Brothers Medical Center | Elk Grove Village | Illinois | 60007 | — |
| Evanston Hospital/NorthShore Univ. Health System | Evanston | Illinois | 60210 | — |
| Advocate Lutheran General Hospital | Park Ridge | Illinois | 60068 | — |
| Carle Foundation Hospital | Urbana | Illinois | 61801 | — |
| Maine Medical Center | Portland | Maine | 04102 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Beaumont Hospital | Royal Oak | Michigan | 48072 | — |
| Ascension St. Mary's Hospital | Saginaw | Michigan | 48601 | — |
| Minneapolis Heart Institute | Minneapolis | Minnesota | — | — |
| Mayo Clinic - Rochester | Rochester | Minnesota | 55905 | — |
| HealthEast Medical Research Institute | Saint Paul | Minnesota | 55102 | — |
| Washington University in St. Louis | St Louis | Missouri | 63110 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| Morristown Memorial | Morristown | New Jersey | 07962 | — |
| NYU Langone Medical Center | New York | New York | 10016 | — |
| Columbia University Medical Center/New York Presbyterian Hospital | New York | New York | 10032 | — |
| St. Francis Hospital | Roslyn | New York | 11576 | — |
| Oregon Health Science University (OHSU) | Portland | Oregon | 97239 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| UPMC Presbyterian | Pittsburgh | Pennsylvania | 15213 | — |
| PinnacleHealth Cardiovascular Institute | Wormleysburg | Pennsylvania | 17043 | — |
| WellSpan York Hospital | York | Pennsylvania | 17405 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02904 | — |
| Vanderbilt Heart and Vascular | Nashville | Tennessee | 37203 | — |
| Seton Medical Center Austin | Austin | Texas | 78705 | — |
| IHC Health Services, Inc. dba Intermountain Medical Center | Murray | Utah | 84107 | — |
| University of Vermont Medical Center | Burlington | Vermont | 05401 | — |
| Virginia Commonwealth University (VCU) | Richmond | Virginia | 23298 | — |
| Swedish Medical Center | Seattle | Washington | 98125 | — |
| Oklahoma Heart Hospital | Milwaukee | Wisconsin | 53211 | — |
| Advocate Aurora- St. Lukes | Milwaukee | Wisconsin | 53215 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02661451, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 27, 2024 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02661451 live on ClinicalTrials.gov.