A Trial Comparing Cardiovascular Safety of Degarelix Versus Leuprolide in Patients With Advanced Prostate Cancer and Cardiovascular Disease
Public ClinicalTrials.gov record NCT02663908. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multi-Center, Randomized, Assessor-Blind, Controlled Trial Comparing the Occurrence of Major Adverse Cardiovascular Events (MACEs) in Patients With Prostate Cancer and Cardiovascular Disease Receiving Degarelix (Gonadotropin-Releasing Hormone (GnRH) Receptor Antagonist) or Leuprolide (GnRH Receptor Agonist)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this trial is to test if a marketed drug for advanced prostate cancer (FIRMAGON) can reduce the risk of cardiovascular complications as compared to another marketed drug for advanced prostate cancer (LUPRON DEPOT) in subjects with prostate cancer and cardiovascular disease.
Study identification
- NCT ID
- NCT02663908
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 545 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 19, 2016 (Actual)
- Primary completion
- Mar 29, 2021 (Actual)
- Completion
- Mar 29, 2021 (Actual)
- Last update posted
- Jun 29, 2022
2016 – 2021
United States locations
- U.S. sites
- 48
- U.S. states
- 25
- U.S. cities
- 45
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Urology Center of Alabama PC | Birmingham | Alabama | 35209 | — |
| Arizona Institute of Urology | Tucson | Arizona | 85704 | — |
| Urological Associates of Southern Arizona | Tucson | Arizona | 85715 | — |
| University of Arizona College of Medicine | Tucson | Arizona | 85724 | — |
| Urology Associates, PA | Little Rock | Arkansas | 72211 | — |
| Pacific Cancer Medical Center, Inc. | Anaheim | California | 92801 | — |
| San Diego Clinical Trials | La Mesa | California | 91942 | — |
| Clinical Trials Research | Lincoln | California | 95648 | — |
| VA Greater Los Angeles Healthcare System | Los Angeles | California | 90073 | — |
| University of California, Irvine Medical Center | Orange | California | 92868 | — |
| Skyline Urology | Torrance | California | 90505 | — |
| Innovative Clinical Research Institute | Whittier | California | 90603 | — |
| Urology Center of Colorado | Denver | Colorado | 80211 | — |
| Yale University | New Haven | Connecticut | 06519 | — |
| Urologic Surgeons of Washington | Washington D.C. | District of Columbia | 20036 | — |
| San Marcus Research Clinic Inc | Miami | Florida | 33014 | — |
| Mount Sinai Comprehensive Cancer Center | Miami Beach | Florida | 33140 | — |
| Clinical Research Center of Florida | Pompano Beach | Florida | 33060 | — |
| Florida Urology Partners | Tampa | Florida | 33615 | — |
| Comprehensive Urologic Care | Lake Barrington | Illinois | 60010 | — |
| Springfield Clinic LLP | Springfield | Illinois | 62703 | — |
| Urology of Indiana LLC | Greenwood | Indiana | 46032 | — |
| First Urology PSC | Jeffersonville | Indiana | 47130 | — |
| Iowa Clinic | West Des Moines | Iowa | 50266 | — |
| University of Kansas Medical Center Research Institute, Inc. | Kansas City | Kansas | 66160 | — |
| Kansas City Urology Care | Lenexa | Kansas | 66214 | — |
| Regional Urology, LLC | Shreveport | Louisiana | 71106 | — |
| Chesapeake Urology Associates, P.A. | Towson | Maryland | 21204 | — |
| Delaware Valley Urology LLC Westhampton | Mount Laurel | New Jersey | 08054 | — |
| Holy Name Medical Center | Teaneck | New Jersey | 07666 | — |
| Urology Group of New Mexico PC | Albuquerque | New Mexico | 87109 | — |
| Advanced Urology Centers of New York Elmont Division | Elmont | New York | 11003 | — |
| SUNY Upstate Medical University | Syracuse | New York | 13210 | — |
| Montefiore Medical Center PRIME | The Bronx | New York | 10461 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Veterans Affairs Medical Center-Salisbury, NC | Salisbury | North Carolina | 28144 | — |
| Signal Point Clinical Research Center | Dayton | Ohio | 45409 | — |
| Clinical Research Solutions PC | Middleburg Heights | Ohio | 44130 | — |
| Urologic Consultants of Southeaster PA LLP | Bala-Cynwyd | Pennsylvania | 19004 | — |
| Lancaster Urology | Lancaster | Pennsylvania | 17604 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Ralph H. Johnson VA Medical Center | Charleston | South Carolina | 29401 | — |
| Medical University of South Carolina (MUSC) | Charleston | South Carolina | 29425 | — |
| Erlanger Health System | Chattanooga | Tennessee | 37403 | — |
| Urology of Virginia | Norfolk | Virginia | 23462 | — |
| Seattle Urology Research Center | Burien | Washington | 98166 | — |
| University of Washington School of Medicine | Seattle | Washington | 98195 | — |
| Medical College of Wisconsin, Inc. | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 85 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02663908, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 29, 2022 · Synced Oct 30, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02663908 live on ClinicalTrials.gov.