A Study Evaluating Regorafenib Following Completion of Standard Chemotherapy for Patients With Colon Cancer
Public ClinicalTrials.gov record NCT02664077. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
A Phase III Randomized Placebo-Controlled Study Evaluating Regorafenib Following Completion of Standard Chemotherapy for Patients With Stage III Colon Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is a randomized, double-blind, post-chemotherapy, adjuvant phase III clinical trial. The primary aim of this study is to determine the value of regorafenib in improving disease-free survival (DFS). Patients with Stage III (IIIB or IIIC) colon cancer as defined by the 7th Edition of the American Joint Committee on Cancer (AJCC) Cancer Staging Manual are randomized 1:1 to placebo or the experimental agent regorafenib following completion of at least four months of standard adjuvant therapy (e.g., 5-fluorouracil, leucovorin, oxaliplatin (FOLFOX) , capecitabine, oxaliplatin (CapeOx), and other).
Study identification
- NCT ID
- NCT02664077
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 34 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2016 (Type not available)
- Primary completion
- Oct 2019 (Actual)
- Completion
- Oct 2019 (Actual)
- Last update posted
- Apr 14, 2022
2016 – 2019
United States locations
- U.S. sites
- 51
- U.S. states
- 26
- U.S. cities
- 50
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| St. Joseph Hospital of Orange | Orange | California | 92868 | — |
| St. Joseph Heritage Healthcare | Santa Rosa | California | 95403 | — |
| Kaiser Permanente Medical Center - Vallejo | Vallejo | California | 94589 | — |
| Colorado Cancer Research Program | Denver | Colorado | 80222 | — |
| Yale University | New Haven | Connecticut | 06510 | — |
| University of Florida | Gainesville | Florida | 32610 | — |
| Mount Sinai Comprehensive Cancer Center | Miami Beach | Florida | 33140 | — |
| Memorial Health University Medical Center | Savannah | Georgia | 31404 | — |
| Cancer Care Specialists of Illinois - Decatur Memorial Hospital | Decatur | Illinois | 62526 | — |
| Edward Hospital Cancer Center | Naperville | Illinois | 60540-7499 | — |
| Carle Cancer Center | Urbana | Illinois | 61801 | — |
| Northern Indiana Cancer Research Consortium | South Bend | Indiana | 46628 | — |
| Oncology Associates at Mercy Medical Center | Cedar Rapids | Iowa | 52403 | — |
| Genesis Medical Center - West Campus | Davenport | Iowa | 52804 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| Covenant Cancer Treatment Center | Waterloo | Iowa | 50702 | — |
| Norton Cancer Institute, Norton Healthcare Pavilion | Louisville | Kentucky | 40202 | — |
| Tulane University Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| New England Cancer Specialists | Scarborough | Maine | 04074 | — |
| Berkshire Medical Center Cancer and Infusion Center | Pittsfield | Massachusetts | 01201 | — |
| Breslin Cancer Center | Lansing | Michigan | 48910 | — |
| Metro Minnesota Community Oncology Research Consortium | Saint Louis Park | Minnesota | 55416 | — |
| Missouri Valley Cancer Consortium | Omaha | Nebraska | 68106 | — |
| Nevada Cancer Research Foundation, Inc. | Las Vegas | Nevada | 89106 | — |
| MD Anderson Cancer Center at Cooper | Camden | New Jersey | 08103 | — |
| Monmouth Medical Center | Long Branch | New Jersey | 07740-6395 | — |
| Newark Beth Israel Medical Center | Newark | New Jersey | 07112 | — |
| Community Medical Center | Toms River | New Jersey | 08755 | — |
| Waverly Hematology Oncology | Cary | North Carolina | 27511 | — |
| CaroMont Regional Medical Center | Gastonia | North Carolina | 28054 | — |
| Margaret R. Pardee Memorial Hospital | Hendersonville | North Carolina | 28791 | — |
| First Health of the Carolinas Cancer Center | Pinehurst | North Carolina | 28374 | — |
| Wake Forest Baptist Health | Winston-Salem | North Carolina | 27157 | — |
| James Cancer Hospital and Solove Research Institute at the Ohio State University Comprehensive Cancer Center | Columbus | Ohio | 43210 | — |
| Toledo Clinic Cancer Center | Toledo | Ohio | 43623 | — |
| Abington Hospital -Jefferson South | Abington | Pennsylvania | 19001 | — |
| Penn State Cancer Institute at Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033-0850 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| UPMC Cancer Centers | Pittsburgh | Pennsylvania | 15232 | — |
| Guthrie Medical Group, PC | Sayre | Pennsylvania | 18840 | — |
| Scranton Hematology Oncology | Scranton | Pennsylvania | 18510 | — |
| Reading Hospital - McGlinn Cancer Institute | West Reading | Pennsylvania | 19611 | — |
| AnMed Health Cancer Center | Anderson | South Carolina | 29621 | — |
| McLeod Cancer Center for Treatment and Research | Florence | South Carolina | 29502 | — |
| Wellmont Medical Associates Oncology and Hematology | Kingsport | Tennessee | 37660 | — |
| Thompson Cancer Survival Center | Knoxville | Tennessee | 37916 | — |
| Joe Arrington Cancer Research and Treatment Center | Lubbock | Texas | 79410 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23298 | — |
| West Virginia University | Morgantown | West Virginia | 26506 | — |
| Green Bay Oncology, Ltd. - St. Vincent Hospital | Green Bay | Wisconsin | 54301 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02664077, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 14, 2022 · Synced Nov 7, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02664077 live on ClinicalTrials.gov.