CGX1321 in Subjects With Advanced Solid Tumors and CGX1321 With Pembrolizumab or Encorafenib + Cetuximab in Subjects With Advanced GI Tumors (Keynote 596)
Public ClinicalTrials.gov record NCT02675946. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1 Open-label Dose Escalation Study of CGX1321 in Subjects With Advanced Solid Tumors With Expansion in Advanced Gastrointestinal Tumors and Phase 1b Study of CGX1321 in Combination With Pembrolizumab in Subjects With Advanced Colorectal Cancer or in Combination With Encorafenib + Cetuximab in Subjects With BRAFV600E Mutated Advanced Colorectal Cancer
Study identification
- NCT ID
- NCT02675946
- Recruitment status
- Not listed
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Curegenix Inc.
- Industry
- Enrollment
- 72 participants
Conditions and interventions
Conditions
Interventions
- CGX1321 Drug
- Pembrolizumab Drug
- cetuximab Drug
- encorafenib Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 31, 2016
- Primary completion
- Feb 28, 2023
- Completion
- Feb 28, 2023
- Last update posted
- Jan 25, 2022
2016 – 2023
United States locations
- U.S. sites
- 25
- U.S. states
- 20
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Memorial Care | Long Beach | California | 90806 | Not yet recruiting |
| St. Joseph's Santa Rosa | Santa Rosa | California | 95403 | Not yet recruiting |
| Sarah Cannon Research Institute at HealthONE | Denver | Colorado | 80218 | Completed |
| Hartford Health Care | Hartford | Connecticut | 06106 | Not yet recruiting |
| Lombardi Comprehensive Cancer Center | Washington D.C. | District of Columbia | 20007 | Recruiting |
| Not listed | Brooksville | Florida | 34613 | Not yet recruiting |
| CSNF Cancer Specialists of North Florida (QCCA) | Jacksonville | Florida | 32256 | Not yet recruiting |
| Ocala Oncology | Ocala | Florida | 34474 | Not yet recruiting |
| University Cancer & Blood Center (QCCA) | Athens | Georgia | 30607 | Not yet recruiting |
| Hawaii Cancer Center | Honolulu | Hawaii | 96813 | Not yet recruiting |
| Edward H. Kaplan MD and Associates | Skokie | Illinois | 60076 | Not yet recruiting |
| Goshen Health | Goshen | Indiana | 46526 | Not yet recruiting |
| Community Health Network | Indianapolis | Indiana | 46250 | Not yet recruiting |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Baltimore | Maryland | 21287 | Recruiting |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | Recruiting |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | Recruiting |
| Nebraska Cancer Specialists (QCCA) | Omaha | Nebraska | 68130 | Not yet recruiting |
| Summit Medical Group | Florham Park | New Jersey | 07932 | Not yet recruiting |
| Duke Cancer Center, Duke University Medical Center | Durham | North Carolina | 27710 | Recruiting |
| Gettysburg Cancer Center | Gettysburg | Pennsylvania | 17325 | Not yet recruiting |
| Sanford Health | Sioux Falls | South Dakota | 57104 | Not yet recruiting |
| Baptist Cancer Center | Memphis | Tennessee | 38120 | Not yet recruiting |
| START (South Texas Accelerated Research Therapeutics, LLC) | San Antonio | Texas | 78229 | Completed |
| Northwest Medical Specialists (QCCA) | Tacoma | Washington | 98405 | Not yet recruiting |
| University of Wisconsin Carbone Cancer Center | Madison | Wisconsin | 53792 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02675946, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 25, 2022 · Synced May 5, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02675946 live on ClinicalTrials.gov.