Neuroblastoma Maintenance Therapy Trial
Public ClinicalTrials.gov record NCT02679144. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
NMTT- Neuroblastoma Maintenance Therapy Trial Using Difluoromethylornithine (DFMO)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Difluoromethylornithine (DFMO) will be used in an open label, single agent, multicenter, study for patients with neuroblastoma in remission. In this study subjects will receive 730 Days of oral difluoromethylornithine (DFMO) at a dose of 750 mg/m2 ± 250 mg/m2 BID (strata 1, 2, 3, and 4) OR 2500 mg/m2 BID (stratum 1B) on each day of study. This study will focus on the use of DFMO in high risk neuroblastoma patients that are in remission as a strategy to prevent recurrence.
Study identification
- NCT ID
- NCT02679144
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 441 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 1 Year to 30 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 2016 (Actual)
- Primary completion
- Feb 2028 (Estimated)
- Completion
- Feb 2033 (Estimated)
- Last update posted
- Sep 3, 2026
2016 – 2033
United States locations
- U.S. sites
- 41
- U.S. states
- 29
- U.S. cities
- 41
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama, Children's of Alabama | Birmingham | Alabama | 35233 | — |
| Arkansas Children's Hospital | Little Rock | Arkansas | 72202 | — |
| UCSF Benioff Children's Hospital Oakland- | Oakland | California | 94609 | — |
| Rady Children's Hospital | San Diego | California | 92123 | — |
| Rocky Mountain Pediatric Hematology | Denver | Colorado | 80205 | — |
| Connecticut Children's Hospital | Hartford | Connecticut | 06106 | — |
| University of Florida | Gainesville | Florida | 32611 | — |
| Arnold Palmer Hospital for Children | Orlando | Florida | 32806 | — |
| All Children's Hospital Johns Hopkins Medicine | St. Petersburg | Florida | 33701 | — |
| St. Joseph's Children's Hospital | Tampa | Florida | 33614 | — |
| Augusta University Health | Augusta | Georgia | 30912 | — |
| Kapiolani Medical Center for Women and Children | Honolulu | Hawaii | 96813 | — |
| St. Lukes | Boise | Idaho | 83712 | — |
| Advocate Aurora Research Institute | Chicago | Illinois | 60453 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| Kentucky Children's Hospital | Lexington | Kentucky | 40536 | — |
| Norton Children's Research Institute/Affiliated with University of Louisville School of Medicine | Louisville | Kentucky | 40202 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Helen DeVos Children's Hospital | Grand Rapids | Michigan | 49503 | — |
| Children's Hospital and Clinics of Minnesota | Minneapolis | Minnesota | 55404 | — |
| Children's Mercy Hospitals and Clinics | Kansas City | Missouri | 64108 | — |
| Cardinal Glennon Children's Medical Center | St Louis | Missouri | 63104 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| NYU Langone Health Hassenfeld Children's Hospital | New York | New York | 10016 | — |
| The Children's Hospital at Montefiore | The Bronx | New York | 10467 | — |
| Levine Children's Hospital | Charlotte | North Carolina | 28204 | — |
| Duke University | Durham | North Carolina | 27708 | — |
| Cleveland Clinic Children's | Cleveland | Ohio | 44106 | — |
| Nationwide Children's Hospital | Columbus | Ohio | 43205 | — |
| Randall Children's Hospital | Portland | Oregon | 97227 | — |
| Penn State Milton S. Hershey Medical Center and Children's Hospital | Hershey | Pennsylvania | 17033 | — |
| Hasbro Children's Hospital | Providence | Rhode Island | 02903 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Monroe Carrell Jr. Children's Hospital at Vanderbilt | Nashville | Tennessee | 37232 | — |
| Dell Children's Blood and Cancer Center | Austin | Texas | 78723 | — |
| Children's Medical Center | Dallas | Texas | 75235 | — |
| Texas Children's Cancer and Hematology Centers | Houston | Texas | 77030 | — |
| Primary Children's Hospital | Salt Lake City | Utah | 84113 | — |
| Children's Hospital of The King's Daughters | Norfolk | Virginia | 23507 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23284 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02679144, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 3, 2026 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02679144 live on ClinicalTrials.gov.