ClinicalTrials.gov record
Efficacy and Safety Study to Evaluate Vadadustat for the Maintenance Treatment of Anemia in Participants With Non-dialysis-dependent Chronic Kidney Disease (NDD-CKD)
ClinicalTrials.gov ID: NCT02680574
Public ClinicalTrials.gov record NCT02680574. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 3, Randomized, Open-label, Active-controlled Study Evaluating the Efficacy and Safety of Oral Vadadustat for the Maintenance Treatment of Anemia in Subjects With Non-dialysis-dependent Chronic Kidney Disease (NDD-CKD) (PRO2TECT-CONVERSION)
Study identification
- NCT ID
- NCT02680574
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Akebia Therapeutics
- Industry
- Enrollment
- 1,725 participants
Conditions and interventions
Interventions
- Vadadustat Drug
- Darbepoetin alfa Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 31, 2016
- Primary completion
- Jun 17, 2020
- Completion
- Jul 30, 2020
- Last update posted
- Jun 26, 2022
2016 – 2020
United States locations
- U.S. sites
- 219
- U.S. states
- 38
- U.S. cities
- 161
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Birmingham | Alabama | 35211 | — |
| Research Site | Huntsville | Alabama | 35805 | — |
| Research Site | Tuscumbia | Alabama | 35674 | — |
| Research Site | Glendale | Arizona | 85306 | — |
| Research Site | Mesa | Arizona | 85210 | — |
| Research Site | Phoenix | Arizona | 85027 | — |
| Research Site | Tucson | Arizona | 85718 | — |
| Research Site | Tucson | Arizona | 85724 | — |
| Research Site | Anaheim | California | 92801 | — |
| Research Site | Bakersfield | California | 93309 | — |
| Research Site #1 | Chula Vista | California | 91910 | — |
| Research Site #2 | Chula Vista | California | 91910 | — |
| Research Site | El Centro | California | 92243 | — |
| Research Site | Fountain Valley | California | 92708 | — |
| Research Site | Glendale | California | 91206 | — |
| Research Site | Granada Hills | California | 91344 | — |
| Research Site | La Mesa | California | 91942 | — |
| Research Site | Laguna Hills | California | 92653 | — |
| Research Site | Long Beach | California | 90807 | — |
| Research Site | Long Beach | California | 92886 | — |
| Research Site | Los Angeles | California | 90048 | — |
| Research Site | Lynwood | California | 90260 | — |
| Research Site #1 | Northridge | California | 91324 | — |
| Research Site #2 | Northridge | California | 91324 | — |
| Research Site | Riverside | California | 92505 | — |
| Research Site | Roseville | California | 95661 | — |
| Research Site | Salinas | California | 93901 | — |
| Research Site | San Diego | California | 92103-6204 | — |
| Research Site #1 | San Dimas | California | 91773 | — |
| Research Site #2 | San Dimas | California | 91773 | — |
| Research Site | Santa Ana | California | 92704 | — |
| Research Site | Santa Monica | California | 90404 | — |
| Research Site | Sherman Oaks | California | 91403 | — |
| Research Site | Thousand Oaks | California | 91360 | — |
| Research Site | Whittier | California | 90603 | — |
| Research Site | Whittier | California | 99999 | — |
| Research Site | Arvada | Colorado | 80002 | — |
| Research Site | Denver | Colorado | 80230 | — |
| Research Site | Westminster | Colorado | 80031 | — |
| Research Site | Stamford | Connecticut | 06902 | — |
| Research Site | Waterbury | Connecticut | 06708 | — |
| Research Site | Bradenton | Florida | 34209 | — |
| Research Site | Brandon | Florida | 33511 | — |
| Research Site | Cooper City | Florida | 33024 | — |
| Research Site #1 | Coral Gables | Florida | 33134 | — |
| Research Site #2 | Coral Gables | Florida | 33134 | — |
| Research Site | Coral Springs | Florida | 33065 | — |
| Research Site | Coral Springs | Florida | 33071 | — |
| Research Site | Doral | Florida | 33166 | — |
| Research Site | Edgewater | Florida | 32132 | — |
| Research Site | Hialeah | Florida | 33010 | — |
| Research Site #1 | Hialeah | Florida | 33012 | — |
| Research Site #2 | Hialeah | Florida | 33012 | — |
| Research Site #3 | Hialeah | Florida | 33012 | — |
| Research Site | Hialeah | Florida | 33018 | — |
| Research Site #1 | Hollywood | Florida | 33024 | — |
| Research Site #2 | Hollywood | Florida | 33024 | — |
| Research Site | Jacksonville | Florida | 32204 | — |
| Research Site #1 | Jacksonville | Florida | 32216 | — |
| Research Site #2 | Jacksonville | Florida | 32216 | — |
| Research Site | Lake Worth | Florida | 33467 | — |
| Research Site | Lauderdale Lakes | Florida | 33313 | — |
| Research Site | Miami | Florida | 33122 | — |
| Research Site | Miami | Florida | 33125-4141 | — |
| Research Site #1 | Miami | Florida | 33126 | — |
| Research Site #2 | Miami | Florida | 33126 | — |
| Research Site | Miami | Florida | 33133 | — |
| Research Site | Miami | Florida | 33134 | — |
| Research Site | Miami | Florida | 33135 | — |
| Research Site | Miami | Florida | 33143 | — |
| Research Site #1 | Miami | Florida | 33144 | — |
| Research Site #2 | Miami | Florida | 33144 | — |
| Research Site | Miami | Florida | 33145 | — |
| Research Site | Miami | Florida | 33150 | — |
| Research Site | Miami | Florida | 33157 | — |
| Research Site | Miami | Florida | 33165 | — |
| Research Site | Miami | Florida | 33169 | — |
| Research Site | Miami | Florida | 33173 | — |
| Research Site #1 | Miami | Florida | 33175 | — |
| Research Site #2 | Miami | Florida | 33175 | — |
| Research Site | Miami Beach | Florida | 33140 | — |
| Research Site | Miami Lakes | Florida | 33014 | — |
| Research Site #1 | Miami Lakes | Florida | 33016 | — |
| Research Site #2 | Miami Lakes | Florida | 33016 | — |
| Research Site | Pembroke Pines | Florida | 33026 | — |
| Research Site | Pompano Beach | Florida | 33060 | — |
| Research Site | Port Charlotte | Florida | 33952 | — |
| Research Site | Tampa | Florida | 33604 | — |
| Research Site | Tampa | Florida | 33612 | — |
| Research Site | Tampa | Florida | 33614 | — |
| Research Site | Atlanta | Georgia | 30338 | — |
| Research Site | Atlanta | Georgia | 30342 | — |
| Research Site | Atlanta | Georgia | 30350 | — |
| Research Site | Augusta | Georgia | 30909 | — |
| Research Site | Columbus | Georgia | 31901 | — |
| Research Site #1 | Columbus | Georgia | 31904 | — |
| Research Site #2 | Columbus | Georgia | 31904 | — |
| Research Site #1 | Lawrenceville | Georgia | 30046 | — |
| Research Site #2 | Lawrenceville | Georgia | 30046 | — |
| Research Site | Macon | Georgia | 31217 | — |
| Research Site | Meridian | Idaho | 83642 | — |
| Research Site | Chicago | Illinois | 60637 | — |
| Research Site | Elk Grove Village | Illinois | 60007 | — |
| Research Site | Evanston | Illinois | 60201 | — |
| Research Site | McHenry | Illinois | 60050 | — |
| Research Site | Peoria | Illinois | 61603 | — |
| Research Site | Anderson | Indiana | 46011 | — |
| Research Site | Fort Wayne | Indiana | 46804 | — |
| Research Site | Jeffersonville | Indiana | 47130 | — |
| Research Site #1 | Merrillville | Indiana | 46410 | — |
| Research Site #2 | Merrillville | Indiana | 46410 | — |
| Research Site | Michigan City | Indiana | 46360 | — |
| Research Site | Muncie | Indiana | 47304 | — |
| Research Site | Monroe | Louisiana | 71201 | — |
| Research Site | New Orleans | Louisiana | 70115 | — |
| Research Site | Shreveport | Louisiana | 71101 | — |
| Research Site | Shreveport | Louisiana | 71103 | — |
| Research Site | Portland | Maine | 04102 | — |
| Research Site | Baltimore | Maryland | 21218 | — |
| Research Site | Greenbelt | Maryland | 20770 | — |
| Research Site | Takoma Park | Maryland | 20912 | — |
| Research Site | Methuen | Massachusetts | 01844 | — |
| Research Site | Plymouth | Massachusetts | 02360 | — |
| Research Site | Springfield | Massachusetts | 01107 | — |
| Research Site | Detroit | Michigan | 48202 | — |
| Research Site | Pontiac | Michigan | 48341 | — |
| Research Site | Port Huron | Michigan | 91344 | — |
| Research Site | Roseville | Michigan | 48066 | — |
| Research Site | Minneapolis | Minnesota | 55404 | — |
| Research Site | Saint Paul | Minnesota | 55102 | — |
| Research Site | Gulfport | Mississippi | 39501 | — |
| Research Site | Columbia | Missouri | 65201 | — |
| Research Site | Kansas City | Missouri | 64111 | — |
| Research Site | Kansas City | Missouri | 64128 | — |
| Research Site | Butte | Montana | 59701 | — |
| Research Site | Lincoln | Nebraska | 68510 | — |
| Research Site | Omaha | Nebraska | 68124 | — |
| Research Site #1 | Las Vegas | Nevada | 89106 | — |
| Research Site #2 | Las Vegas | Nevada | 89106 | — |
| Research Site | Portsmouth | New Hampshire | 03801 | — |
| Research Site | Berlin | New Jersey | 08009 | — |
| Research Site | Voorhees Township | New Jersey | 08043 | — |
| Research Site | Albuquerque | New Mexico | 87106 | — |
| Research Site | Albuquerque | New Mexico | 87108 | — |
| Research Site | Albuquerque | New Mexico | 87109 | — |
| Research Site | Santa Fe | New Mexico | 87505 | — |
| Research Site | Flushing | New York | 11355 | — |
| Research Site | Laurelton | New York | 11413 | — |
| Research Site | Mineola | New York | 11501 | — |
| Research Site | New York | New York | 10010 | — |
| Research Site | The Bronx | New York | 10467 | — |
| Research Site | Asheville | North Carolina | 28801 | — |
| Research Site #1 | Greenville | North Carolina | 27834 | — |
| Research Site #2 | Greenville | North Carolina | 27834 | — |
| Research Site | Jacksonville | North Carolina | 28546 | — |
| Research Site | Kinston | North Carolina | 28504 | — |
| Research Site | Morehead City | North Carolina | 28557 | — |
| Research Site | New Bern | North Carolina | 28560 | — |
| Research Site | Wilmington | North Carolina | 28401 | — |
| Research Site | Winston-Salem | North Carolina | 27103 | — |
| Research Site | Akron | Ohio | 44302 | — |
| Research Site | Columbus | Ohio | 43203 | — |
| Research Site | Marion | Ohio | 43302 | — |
| Research Site | Maumee | Ohio | 43537 | — |
| Research Site | Portland | Oregon | 97216 | — |
| Research Site | Doylestown | Pennsylvania | 18901 | — |
| Research Site | Jersey Shore | Pennsylvania | 17740 | — |
| Research Site | Philadelphia | Pennsylvania | 19140 | — |
| Research Site | East Providence | Rhode Island | 02915 | — |
| Research Site | Providence | Rhode Island | 02908 | — |
| Research Site | Anderson | South Carolina | 29625 | — |
| Research Site | Columbia | South Carolina | 29203 | — |
| Research Site | Orangeburg | South Carolina | 29118 | — |
| Research Site | Sumter | South Carolina | 29150-1900 | — |
| Research Site | West Columbia | South Carolina | 29169 | — |
| Research Site | Chattanooga | Tennessee | 37408 | — |
| Research Site | Knoxville | Tennessee | 37923 | — |
| Research Site | Memphis | Tennessee | 38104 | — |
| Research Site | Nashville | Tennessee | 37205 | — |
| Research Site | Arlington | Texas | 76015 | — |
| Research Site | Dallas | Texas | 75220 | — |
| Research Site | Dallas | Texas | 75390 | — |
| Research Site | DeSoto | Texas | 75115 | — |
| Research Site | El Paso | Texas | 79935 | — |
| Research Site | Fort Worth | Texas | 76104 | — |
| Research Site | Gonzales | Texas | 78629 | — |
| Research Site | Greenville | Texas | 75401 | — |
| Research Site | Greenville | Texas | 75402 | — |
| Research Site | Houston | Texas | 33143 | — |
| Research Site #1 | Houston | Texas | 77004 | — |
| Research Site #2 | Houston | Texas | 77004 | — |
| Research Site | Houston | Texas | 77054 | — |
| Research Site | Lewisville | Texas | 75057 | — |
| Research Site #1 | McAllen | Texas | 78503 | — |
| Research Site #2 | McAllen | Texas | 78503 | — |
| Research Site | McKinney | Texas | 75069 | — |
| Research Site | McKinney | Texas | 75071 | — |
| Research Site | Plano | Texas | 75024-5327 | — |
| Research Site | San Antonio | Texas | 78207 | — |
| Research Site | San Antonio | Texas | 78212-4740 | — |
| Research Site | San Antonio | Texas | 78224 | — |
| Research Site | San Antonio | Texas | 78240-1501 | — |
| Research Site | Sherman | Texas | 75090 | — |
| Research Site | Victoria | Texas | 77901 | — |
| Research Site | Clinton | Utah | 84015 | — |
| Research Site | Salt Lake City | Utah | 84115 | — |
| Research Site | St. George | Utah | 84790 | — |
| Research Site | Burlington | Vermont | 05401 | — |
| Research Site | Alexandria | Virginia | 22304 | — |
| Research Site | Arlington | Virginia | 22207 | — |
| Research Site | Danville | Virginia | 24541 | — |
| Research Site | Hampton | Virginia | 23666 | — |
| Research Site | Lansdowne Town Center | Virginia | 20176 | — |
| Research Site | Norfolk | Virginia | 23507 | — |
| Research Site | Salem | Virginia | 24153 | — |
| Research Site | Woodbridge | Virginia | 22191 | — |
| Research Site | Tacoma | Washington | 98405 | — |
| Research Site | Wenatchee | Washington | 98801 | — |
| Research Site | Madison | Wisconsin | 53705 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 284 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02680574, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 26, 2022 · Synced Jul 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02680574 live on ClinicalTrials.gov.