ClinicalTrials.gov record
A Study of Avelumab With Axitinib Versus Sunitinib In Advanced Renal Cell Cancer (JAVELIN Renal 101)
ClinicalTrials.gov ID: NCT02684006
Public ClinicalTrials.gov record NCT02684006. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A PHASE 3, MULTINATIONAL, RANDOMIZED, OPEN-LABEL, PARALLEL-ARM STUDY OF AVELUMAB (MSB0010718C) IN COMBINATION WITH AXITINIB (INLYTA(REGISTERED)) VERSUS SUNITINIB (SUTENT(REGISTERED)) MONOTHERAPY IN THE FIRST-LINE TREATMENT OF PATIENTS WITH ADVANCED RENAL CELL CARCINOMA
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a phase 3 randomized trial evaluating the anti-tumor activity and safety of avelumab in combination with axitinib and of sunitinib monotherapy, administered as first-line treatment, in patients with advanced renal cell carcinoma
Study identification
- NCT ID
- NCT02684006
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 886 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 22, 2016
- Primary completion
- Aug 30, 2023
- Completion
- Jun 25, 2024
- Last update posted
- Jul 29, 2025
2016 – 2024
United States locations
- U.S. sites
- 93
- U.S. states
- 21
- U.S. cities
- 44
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Southern Cancer Center | Daphne | Alabama | 36526 | — |
| Southern Cancer Center | Mobile | Alabama | 36607 | — |
| Southern Cancer Center | Mobile | Alabama | 36608 | — |
| Tower Hematology Oncology Medical Group | Beverly Hills | California | 90211 | — |
| City of Hope National Medical Center | Duarte | California | 91010 | — |
| City of Hope | Duarte | California | 91010 | — |
| Keck Hospital of USC | Los Angeles | California | 90033 | — |
| Los Angeles General Medical Center | Los Angeles | California | 90033 | — |
| USC IDS Pharmacy | Los Angeles | California | 90033 | — |
| USC/Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | — |
| Cedars-Sinai Advanced Health Sciences Pavilion | Los Angeles | California | 90048 | — |
| Cedars-Sinai Medical Center, Samuel Oschin Comprehensive Cancer Institute | Los Angeles | California | 90048 | — |
| Cedars-Sinai | Los Angeles | California | 90048 | — |
| Rocky Mountain Cancer Centers | Aurora | Colorado | 80012 | — |
| University of Colorado Cancer Center Anschutz Cancer Pavilion | Aurora | Colorado | 80045 | — |
| University of Colorado Hospital - Clinical Trials Office (CTO) | Aurora | Colorado | 80045 | — |
| University of Colorado Hospital | Aurora | Colorado | 80045 | — |
| Rocky Mountain Cancer Centers | Colorado Springs | Colorado | 80907 | — |
| Georgetown University Medical Center | Washington D.C. | District of Columbia | 20007 | — |
| Moffitt Cancer Center and Research Institute | Tampa | Florida | 33612 | — |
| Emory University Hospital | Atlanta | Georgia | 30322 | — |
| Investigational Drug Service- Emory University | Atlanta | Georgia | 30322 | — |
| The Emory Clinic | Atlanta | Georgia | 30322 | — |
| Winship Cancer Institute, Emory University | Atlanta | Georgia | 30322 | — |
| East Jefferson General Hospital | Metairie | Louisiana | 70006 | — |
| East Jefferson Hematology-Oncology Metairie Physician Service Inc. | Metairie | Louisiana | 70006 | — |
| New England Cancer Specialists | Kennebunk | Maine | 04043 | — |
| New England Cancer Specialists | Scarborough | Maine | 04074 | — |
| New England Cancer Specialists | Topsham | Maine | 04086 | — |
| Oncology Investigational Drug Services- The Sidney Kimmel Cancer Center at Johns Hopkins Hospital | Baltimore | Maryland | 21231 | — |
| Johns Hopkins Hospital | Baltimore | Maryland | 21287 | — |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Baltimore | Maryland | 21287 | — |
| Massachusetts General Hospital (MGH) | Boston | Massachusetts | 02114 | — |
| Massachusetts General Hospital Clinical Trials Pharmacy | Boston | Massachusetts | 02114 | — |
| Brigham & Women's Hospital | Boston | Massachusetts | 02115 | — |
| Beth Israel Deaconess Medical Center (BIDMC) | Boston | Massachusetts | 02215 | — |
| Beth Israel Deaconess Medical Center Pharmacy - BIDMC | Boston | Massachusetts | 02215 | — |
| Dana - Farber Cancer Institute | Boston | Massachusetts | 02215 | — |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | — |
| Baystate Franklin Medical Center | Greenfield | Massachusetts | 01301 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Barnes-Jewish Hospital, Siteman Cancer Center - St. Peters | City of Saint Peters | Missouri | 63376 | — |
| Barnes-Jewish Hospital, Siteman Cancer Center - West County | Creve Coeur | Missouri | 63141 | — |
| Barnes-Jewish Hospital, Siteman Cancer Center | St Louis | Missouri | 63110 | — |
| Washington University Infusion Center Pharmacy | St Louis | Missouri | 63110 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Barnes-Jewish Hospital, Siteman Cancer Center - South County | St Louis | Missouri | 63129 | — |
| St. Vincent Healthcare | Billings | Montana | 59101 | — |
| Intermountain Health St. Vincent Regional Hospital - Cancer Centers of Montana | Billings | Montana | 59102 | — |
| Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | 75063 | — |
| Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | 89148 | — |
| Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | 89169 | — |
| New York Oncology Hematology, P.C. | Albany | New York | 12206 | — |
| New York Oncology Hematology, PC | Albany | New York | 12208 | — |
| New York Oncology Hematology, P.C. | Clifton Park | New York | 12065 | — |
| Memorial Sloan Kettering Cancer Center - Investigational Drug Service Pharmacy | Long Island City | New York | 11101 | — |
| Laura & Isaac Perlmutter Cancer Center at NYU Langone | New York | New York | 10016 | — |
| NYU Investigational Pharmacy | New York | New York | 10016 | — |
| NYU Langone Medical Center | New York | New York | 10016 | — |
| MSKCC-Monitoring Suite | New York | New York | 10017 | — |
| Evelyn H. Lauder Breast and Imaging Center | New York | New York | 10065 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | — |
| Sidney Kimmel Center for Prostate and Urologic Cancers | New York | New York | 10065 | — |
| Stony Brook University-Cancer Center | Stony Brook | New York | 11794 | — |
| Stony Brook University | Stony Brook | New York | 11794 | — |
| Novant Health Oncology Specialists | Winston-Salem | North Carolina | 27103 | — |
| Cleveland Clinic Taussig Cancer Center | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| James Cancer Hospital and Solove Research Institute | Columbus | Ohio | 43210 | — |
| The Ohio State University - GU Clinic | Columbus | Ohio | 43210 | — |
| The Ohio State University | Columbus | Ohio | 43210 | — |
| Cancer Care Associates Medical Oncology | Allentown | Pennsylvania | 18104 | — |
| St.Luke's Hospital-Allentown Campus | Allentown | Pennsylvania | 18104 | — |
| Cancer Care Associate Medical Oncology | Bethlehem | Pennsylvania | 18015 | — |
| St. Lukes University Health Network | Bethlehem | Pennsylvania | 18015 | — |
| St.Luke's Cancer Center Anderson | Easton | Pennsylvania | 18045 | — |
| St.Luke's Hospital-Anderson Campus | Easton | Pennsylvania | 18045 | — |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Investigational Drug Service, University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| St.Luke's Quakertown Hospital | Quakertown | Pennsylvania | 18951 | — |
| Henry-Joyce Cancer Clinic | Nashville | Tennessee | 37232 | — |
| Texas Oncology - Baylor Charles A. Sammons Cancer Center | Dallas | Texas | 75246 | — |
| Texas Oncology - Gulf Coast | Houston | Texas | 77024 | — |
| The University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| Investigational Product Center (IPC) | Irving | Texas | 75063 | — |
| Investigational Products Center (IPC) | Irving | Texas | 75063 | — |
| Investigational Products Center (lPC) | Irving | Texas | 75063 | — |
| US Oncology Investigational Products Center (IPC) | Irving | Texas | 75063 | — |
| Joe Arrington Cancer Research and Treatment Center | Lubbock | Texas | 79410 | — |
| Rainier Hematology-Oncology, PC | Puyallup | Washington | 98373 | — |
| Fred Hutchinson Cancer Center | Seattle | Washington | 98109 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
| Northwest Medical Specialties, PLLC | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 177 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02684006, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 29, 2025 · Synced Sep 10, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02684006 live on ClinicalTrials.gov.