Intraoperative Radiotherapy in Newly Diagnosed Glioblastoma Multiforme

ClinicalTrials.gov ID: NCT02685605

Public ClinicalTrials.gov record NCT02685605. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Oct 17, 2026, 6:44 AM EDT

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Official title

A Multicenter Randomized Phase III Trial on INTraoperative RAdiotherapy in Newly Diagnosed GliOblastoma Multiforme (INTRAGO II)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

INTRAGO II resembles a multicentric, prospective, randomized, 2-arm, open-label clinical phase III trial which tests if the median progression-free survival (PFS) of patients with newly diagnosed glioblastoma multiforme (GBM) can be improved by the addition of intraoperative radiotherapy (IORT) to standard radiochemotherapy.

Study identification

NCT ID: NCT02685605
Recruitment status: Active, not recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: Universitätsmedizin Mannheim; Other
Enrollment: 314 participants

Conditions and interventions

Conditions

Glioblastoma

Interventions

Procedure · Radiation · Drug

Eligibility (public fields only)

Age range: 18 Years to 80 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Dec 9, 2016 (Actual)
Primary completion: Nov 2025 (Estimated)
Completion: Jun 2026 (Estimated)
Last update posted: Oct 14, 2025

2016 – 2026

United States locations

U.S. sites: 5
U.S. states: 4
U.S. cities: 5

Facility	City	State	ZIP	Site status
Barrow Neurological Institute (SJHMC)	Phoenix	Arizona	85013	—
Stritch School of Medicine Loyola University	Maywood	Illinois	60153	—
Long Island Jewish Medical Center, North Shore University Hospital	Lake Success	New York	11042	—
Lenox Hill Hospital, Hofstra Northwell School of Medicine	New York	New York	10028	—
West Virginia University	Morgantown	West Virginia	26506-9260	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 14 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT02685605, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Oct 14, 2025 · Synced Oct 17, 2026

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02685605 live on ClinicalTrials.gov.

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