Zimura in Participants With Geographic Atrophy Secondary to Dry Age-Related Macular Degeneration
Public ClinicalTrials.gov record NCT02686658. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2/3 Randomized, Double-Masked, Controlled Trial to Assess the Safety and Efficacy of Intravitreous Administration of Zimura™ (Anti-C5 Aptamer) in Patients With Geographic Atrophy Secondary to Dry Age-Related Macular Degeneration
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objectives of this study were to evaluate the safety and efficacy of Zimura intravitreal (IVT) administration when administered in participants with geographic atrophy (GA) secondary to dry age-related macular degeneration (AMD).
Study identification
- NCT ID
- NCT02686658
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 286 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 15, 2015 (Actual)
- Primary completion
- Sep 26, 2019 (Actual)
- Completion
- Apr 23, 2020 (Actual)
- Last update posted
- Jun 10, 2025
2015 – 2020
United States locations
- U.S. sites
- 55
- U.S. states
- 21
- U.S. cities
- 51
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Phoenix | Arizona | 85053 | — |
| Not listed | Tucson | Arizona | 85704 | — |
| Not listed | Tucson | Arizona | 85710 | — |
| Not listed | Campbell | California | 95008 | — |
| Not listed | Fresno | California | 93720 | — |
| Not listed | Fullerton | California | 92835 | — |
| Not listed | La Jolla | California | 92093 | — |
| Not listed | Mountain View | California | 94040 | — |
| Not listed | Redlands | California | 92374 | — |
| Not listed | Sacramento | California | 95819 | — |
| Not listed | Sacramento | California | 95841 | — |
| Not listed | Santa Ana | California | 92705 | — |
| Not listed | Denver | Colorado | 80210 | — |
| Not listed | Altamonte Springs | Florida | 32701 | — |
| Not listed | Boynton Beach | Florida | 33426 | — |
| Not listed | Melbourne | Florida | 32901 | — |
| Not listed | St. Petersburg | Florida | 33711 | — |
| Not listed | Stuart | Florida | 34994 | — |
| Not listed | Winter Haven | Florida | 33880 | — |
| Not listed | Augusta | Georgia | 30909 | — |
| Not listed | Marietta | Georgia | 30060 | — |
| Retina Consultants of Hawaii | ‘Aiea | Hawaii | 96701 | — |
| Not listed | West Des Moines | Iowa | 50266 | — |
| Not listed | Shawnee Mission | Kansas | 66204 | — |
| Not listed | Wichita | Kansas | 67214 | — |
| Not listed | Baltimore | Maryland | 21209 | — |
| Not listed | Chevy Chase | Maryland | 20815 | — |
| Not listed | Boston | Massachusetts | 02114 | — |
| Not listed | Springfield | Massachusetts | 01107 | — |
| Not listed | Grand Rapids | Michigan | 49546 | — |
| Not listed | Henderson | Nevada | 89052 | — |
| Not listed | Reno | Nevada | 89502 | — |
| Not listed | Rochester | New York | 14620 | — |
| Not listed | Syracuse | New York | 13224 | — |
| Not listed | Asheville | North Carolina | 28803 | — |
| Not listed | Charlotte | North Carolina | 28210 | — |
| Not listed | Hickory | North Carolina | 28602 | — |
| Not listed | Cincinnati | Ohio | 45242 | — |
| Not listed | Cleveland | Ohio | 44130 | — |
| Not listed | Cleveland | Ohio | 44136 | — |
| Not listed | Portland | Oregon | 97221 | — |
| Not listed | Philadelphia | Pennsylvania | 19107 | — |
| Not listed | West Mifflin | Pennsylvania | 15122 | — |
| Not listed | Ladson | South Carolina | 29456 | — |
| Not listed | West Columbia | South Carolina | 29169 | — |
| Not listed | Abilene | Texas | 79606 | — |
| Not listed | Amarillo | Texas | 79106 | — |
| Not listed | Austin | Texas | 78705 | — |
| Not listed | Grapevine | Texas | 76051 | — |
| Not listed | Houston | Texas | 77030 | — |
| Not listed | The Woodlands | Texas | 77384 | — |
| Not listed | Willow Park | Texas | 76087 | — |
| Not listed | Salt Lake City | Utah | 84107 | — |
| Not listed | Salt Lake City | Utah | 84132 | — |
| Not listed | Richmond | Virginia | 23235 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 23 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02686658, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 10, 2025 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02686658 live on ClinicalTrials.gov.