Efficacy, Safety and Tolerability of PF-06649751 in Parkinson's Disease Patients With Motor Fluctuations
Public ClinicalTrials.gov record NCT02687542. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A 15-WEEK, PHASE 2, DOUBLE BLIND, RANDOMIZED, PLACEBO-CONTROLLED, DOSE RANGING STUDY TO INVESTIGATE THE EFFICACY, SAFETY AND TOLERABILITY OF PF-06649751 IN SUBJECTS WITH MOTOR FLUCTUATIONS DUE TO PARKINSON'S DISEASE
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy, safety and tolerability of PF-06649751 in Parkinson's disease patients who experience motor-fluctuations.
Study identification
- NCT ID
- NCT02687542
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 108 participants
Conditions and interventions
Conditions
Interventions
- Placebo Drug
- PF-06649751 low dose (1 mg QD) Drug
- PF-06649751 middle dose 1 (3 mg QD) Drug
- PF-06649751 middle dose 2 (7 mg QD) Drug
- PF-06649751 high dose (15 mg QD) Drug
Drug
Eligibility (public fields only)
- Age range
- 40 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 3, 2016 (Actual)
- Primary completion
- Nov 10, 2017 (Actual)
- Completion
- Nov 10, 2017 (Actual)
- Last update posted
- Nov 23, 2020
2016 – 2017
United States locations
- U.S. sites
- 33
- U.S. states
- 17
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Xenoscience, Inc | Phoenix | Arizona | 85004 | — |
| St Joseph's Hospital and Medical Center | Phoenix | Arizona | 85013 | — |
| Arcadia Neurology Center | Arcadia | California | 91006 | — |
| Faculty Physicians and Surgeons of Loma Linda University School of Medicine | Loma Linda | California | 92354 | — |
| Hoag Memorial Hospital Presbyterian | Newport Beach | California | 92658 | — |
| Hoag Memorial Hospital | Newport Beach | California | 92663 | — |
| SC3 Research Group, Inc | Pasadena | California | 91105 | — |
| Neurosearch-Torrance | Torrance | California | 90505 | — |
| Associated Neurologists of Southern Connecticut, PC | Fairfield | Connecticut | 06824 | — |
| Parkinson's Disease and Movement Disorders Center of Boca Raton | Boca Raton | Florida | 33486 | — |
| University of Florida Center for Movement Disorders and Neurorestoration | Gainesville | Florida | 32607 | — |
| Neurology Associates of Ormond Beach | Ormond Beach | Florida | 32174 | — |
| University of South Florida | Tampa | Florida | 33613 | — |
| Vero Beach Neurology and Research Institute | Vero Beach | Florida | 32960 | — |
| Atlanta Center for Medical Research | Atlanta | Georgia | 30331 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Indiana University Health Neuroscience Center | Indianapolis | Indiana | 46202 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| CRI Worldwide, LLC | Marlton | New Jersey | 08053 | — |
| Dent Neurologic Institute | Amherst | New York | 14226 | — |
| Dent Neurosciences Research Center ,Inc. DBA Dent Neurologic Institute | Amherst | New York | 14226 | — |
| Dent Neurologic Institute | Orchard Park | New York | 14127 | — |
| Duke University Medical center | Durham | North Carolina | 27705 | — |
| Duke University/Duke Neurology/Department of Neurology | Durham | North Carolina | 27705 | — |
| Wake Research Associates, LLC | Raleigh | North Carolina | 27612 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| University of Toledo | Toledo | Ohio | 43614 | — |
| The Movement Disorder Clinic of Oklahoma | Tulsa | Oklahoma | 74136 | — |
| Abington Neurological Associates, Ltd. | Willow Grove | Pennsylvania | 19090 | — |
| Rhode Island Hospital/ Brown University Medical School | Providence | Rhode Island | 02903 | — |
| AS Clinical Research Consultants of North Texas, PLLC | Greenville | Texas | 75401 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Booth Gardner Parkinson's Care Center | Kirkland | Washington | 98034 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 24 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02687542, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 23, 2020 · Synced Oct 31, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02687542 live on ClinicalTrials.gov.