TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

ClinicalTrials.gov ID: NCT02693535

Public ClinicalTrials.gov record NCT02693535. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 8, 2026, 8:10 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Targeted Agent and Profiling Utilization Registry (TAPUR) Study

Study identification

NCT ID: NCT02693535
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: American Society of Clinical Oncology; Other
Enrollment: 4,200 participants

Conditions and interventions

Conditions

Interventions

Abemaciclib Drug
Atezolizumab and Talazoparib Drug
Dabrafenib plus Trametinib Drug
Fam-Trastuzumab Deruxtecan-Nxki (TDxD) Drug
Futibatinib Drug
Nivolumab and Ipilimumab Drug
Olaparib Drug
Palbociclib Drug
Regorafenib Drug
Sunitinib Drug
Talazoparib Drug
Temsirolimus Drug
Trastuzumab and Pertuzumab Drug
Tucatinib plus Trastuzumab Subcutaneous (SC) Drug
Vemurafenib and Cobimetinib Drug

Drug

Eligibility (public fields only)

Age range: 12 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Mar 13, 2016
Primary completion: Dec 30, 2027
Completion: Dec 30, 2028
Last update posted: Apr 1, 2026

2016 – 2028

United States locations

U.S. sites: 174
U.S. states: 28
U.S. cities: 140

Facility	City	State	ZIP	Site status
University of Alabama at Birmingham Comprehensive Cancer Center	Birmingham	Alabama	35294	Recruiting
Cancer Treatment Centers of America-Phoenix	Phoenix	Arizona	85338	Recruiting
Sutter Auburn	Auburn	California	95602	Recruiting
Sutter Alta Bates	Berkeley	California	94705	Recruiting
The Angeles Clinic and Research Institute, A Cedars-Sinai Affiliate	Los Angeles	California	90025	Recruiting
Kaiser Permanente - Oakland Medical Center	Oakland	California	94611	Recruiting
Sutter Palo Alto Medical Foundation: Palo Alto	Palo Alto	California	94301	Recruiting
Kaiser Permanente - Roseville Medical Center	Roseville	California	95661	Recruiting
Sutter Roseville	Roseville	California	95661	Recruiting
Kaiser Permanente - Sacramento Medical Center	Sacramento	California	95814	Recruiting
Sutter Sacramento	Sacramento	California	95816	Recruiting
Kaiser Permanente - South San Francisco Medical Center	San Francisco	California	94080	Recruiting
California Pacific Medical Center Research Institute	San Francisco	California	94115	Recruiting
Kaiser Permanente - San Francisco Medical Center	San Francisco	California	94115	Recruiting
Sutter Cancer Research Consortium	San Francisco	California	94115	Recruiting
Kaiser Permanente - San Jose Medical Center	San Jose	California	95119	Recruiting
Kaiser Permanente - San Leandro Medical Center	San Leandro	California	94577	Recruiting
Sutter Sansum Clinic	Santa Barbara	California	93105	Recruiting
Kaiser Permanente - Santa Clara Medical Center	Santa Clara	California	95051	Recruiting
Sutter Palo Alto Medical Foundation: Santa Cruz	Santa Cruz	California	95065	Recruiting
Sutter Palo Alto Medical Foundation: Fremont	Santa Cruz	California	994538	Recruiting
Sutter Palo Alto Medical Foundation: Sunnyvale	Sunnyvale	California	94086	Recruiting
Kaiser Permanente - Vallejo Medical Center	Vallejo	California	94589	Recruiting
Kaiser Permanente - Walnut Creek Medical Center	Walnut Creek	California	94596	Recruiting
Saint Vincent's Medical Center (SVMC)	Bridgeport	Connecticut	06606	Recruiting
Hartford Hospital	Hartford	Connecticut	06102	Recruiting
Midstate Medical Center (MSMC)	Meriden	Connecticut	06451	Recruiting
The Hospital of Central Connecticut (HOCC) Cancer Center	New Britain	Connecticut	06053	Recruiting
William W. Backus Hospital	Norwich	Connecticut	06360	Recruiting
Charlotte Hungerford	Torrington	Connecticut	06790	Recruiting
Windham Hospital (WH)	Willimantic	Connecticut	06226	Recruiting
Florida Cancer Specialists North / Sarah Cannon Research Institute	Altamonte Springs	Florida	32701	Active, not recruiting
University of Miami/Sylvester Cancer Institute - Aventura	Aventura	Florida	33180	Recruiting
Florida Cancer Specialists South / Sarah Cannon Research Institute	Bonita Springs	Florida	34135	Active, not recruiting
Florida Cancer Specialists South / Sarah Cannon Research Institute	Bradenton	Florida	34211	Active, not recruiting
Florida Cancer Specialists North / Sarah Cannon Research Institute	Brandon	Florida	33511	Active, not recruiting
Florida Cancer Specialists South / Sarah Cannon Research Institute	Cape Coral	Florida	33909	Active, not recruiting
Florida Cancer Specialists North / Sarah Cannon Research Institute	Clearwater	Florida	33761	Active, not recruiting
University of Miami/Sylvester Cancer Institute - Lennar	Coral Gables	Florida	33146	Recruiting
University of Miami/Sylvester Cancer Institute - Deerfield Beach	Deerfield Beach	Florida	33442	Recruiting
Holy Cross Hospital	Fort Lauderdale	Florida	33308	Recruiting
Florida Cancer Specialists South / Sarah Cannon Research Institute	Fort Myers	Florida	33901	Active, not recruiting
Florida Cancer Specialists South / Sarah Cannon Research Institute	Fort Myers	Florida	33905	Active, not recruiting
Florida Cancer Specialists South / Sarah Cannon Research Institute	Fort Myers	Florida	33908	Active, not recruiting
Florida Cancer Specialists North / Sarah Cannon Research Institute	Gainesville	Florida	32605	Active, not recruiting
University of Florida Health	Gainesville	Florida	32610	Recruiting
Florida Cancer Specialists North / Sarah Cannon Research Institute	Largo	Florida	33770	Active, not recruiting
Florida Cancer Specialists North / Sarah Cannon Research Institute	Lecanto	Florida	34461	Active, not recruiting
University of Miami Sylvester Comprehensive Cancer Center	Miami	Florida	33136	Recruiting
University of Miami/Sylvester Cancer Institute - Alex's Place	Miami	Florida	33136	Recruiting
University of Miami/Sylvester Cancer Institute - Griffin Cancer Research Building	Miami	Florida	33136	Recruiting
University of Miami/Sylvester Cancer Institute - Kendall	Miami	Florida	33176	Recruiting
University of Miami/Sylvester Cancer Institute - Sole Mia	Miami	Florida	33181	Recruiting
Florida Cancer Specialists South / Sarah Cannon Research Institute	Naples	Florida	34102	Active, not recruiting
Florida Cancer Specialists North / Sarah Cannon Research Institute	Ocala	Florida	34474	Active, not recruiting
Florida Cancer Specialists North / Sarah Cannon Research Institute	Orange City	Florida	32763	Active, not recruiting
Florida Cancer Specialists North / Sarah Cannon Research Institute	Orlando	Florida	32806	Active, not recruiting
University of Miami/Sylvester Cancer Institute - Plantation	Plantation	Florida	33324	Recruiting
Florida Cancer Specialists South / Sarah Cannon Research Institute	Port Charlotte	Florida	33980	Active, not recruiting
Florida Cancer Specialists South / Sarah Cannon Research Institute	Sarasota	Florida	34232	Active, not recruiting
Florida Cancer Specialists South / Sarah Cannon Research Institute	Sarasota	Florida	34236	Active, not recruiting
Florida Cancer Specialists North / Sarah Cannon Research Institute	St. Petersburg	Florida	33701	Active, not recruiting
Florida Cancer Specialists North / Sarah Cannon Research Institute	Tampa	Florida	33607	Active, not recruiting
Florida Cancer Specialists North / Sarah Cannon Research Institute	Tavares	Florida	32778	Active, not recruiting
Florida Cancer Specialists North / Sarah Cannon Research Institute	The Villages	Florida	32159	Active, not recruiting
Florida Cancer Specialists North / Sarah Cannon Research Institute	Trinity	Florida	34655	Active, not recruiting
Florida Cancer Specialists South / Sarah Cannon Research Institute	Venice	Florida	34285	Active, not recruiting
Florida Cancer Specialists South / Sarah Cannon Research Institute	Venice	Florida	34292	Active, not recruiting
Florida Cancer Specialists North / Sarah Cannon Research Institute	Winter Park	Florida	32789	Active, not recruiting
Cancer Treatment Centers of America - Atlanta	Atlanta	Georgia	30265	Recruiting
Emory University Winship Cancer Institute	Atlanta	Georgia	30322	Recruiting
Gynecologic Oncology and Surgical Specialists at the Lewis Cancer & Research Pavilion	Savannah	Georgia	31405	Recruiting
Lewis Cancer & Research Pavilion at the Melanoma, Skin Cancer & Sarcoma Institute	Savannah	Georgia	31405	Recruiting
Lewis Cancer & Research Pavilion	Savannah	Georgia	31405	Recruiting
Summit Cancer Care	Savannah	Georgia	31405	Recruiting
The Queen's Medical Center - POB I	Honolulu	Hawaii	96813	Recruiting
The Queen's Medical Center - Punchbowl	Honolulu	Hawaii	96813	Recruiting
The Queen's Medical Center - Kuakini	Honolulu	Hawaii	96817	Recruiting
The Queen's Medical Center - West Oahu	‘Ewa Beach	Hawaii	96706	Recruiting
Cancer Treatment Centers of America-Chicago	Chicago	Illinois	60099	Recruiting
Community Health Network (The University of Texas MD Anderson Cancer Center)	Indianapolis	Indiana	46250	Recruiting
Harold Alfond Center for Cancer Care	Augusta	Maine	04330	Recruiting
Jackson Laboratory - Maine Cancer Genomics Initiative	Augusta	Maine	04330	Recruiting
Waldo County General Hospital	Belfast	Maine	04915	Recruiting
SMHC Cancer Care and Blood Disorders -Biddeford	Biddeford	Maine	04005	Recruiting
Northern Light Cancer Care	Brewer	Maine	04412	Recruiting
Raish Peavey Haskell Children's Cancer and Treatment Center	Brewer	Maine	04412	Recruiting
MaineHealth Cancer Care -Brunswick	Brunswick	Maine	04011	Recruiting
New England Cancer Specialist	Kennebunk	Maine	04043	Recruiting
York Hopsital Oncology & Infusion Care in Kittery	Kittery	Maine	03904	Recruiting
Stephens Memorial Hospital	Norway	Maine	04268	Recruiting
Penobscot Bay Medical Center	Rockport	Maine	04856	Recruiting
SMHC Cancer Care and Blood Disorders -Sandford	Sanford	Maine	04073	Recruiting
Maine Children's Cancer Program	Scarborough	Maine	04074	Recruiting
Maine Medical Partner's Women's Health	Scarborough	Maine	04074	Recruiting
New England Cancer Specialist	Scarborough	Maine	04074	Recruiting
MaineHealth Cancer Care -South Portland	South Portland	Maine	04106	Recruiting
New England Cancer Specialist	Topsham	Maine	04086	Recruiting
York Hospital Oncology & Infusion Care in Wells	Wells	Maine	04090	Recruiting
York Hospital Oncology & Infusion Care in York	York Village	Maine	03909	Recruiting
Trinity Health Ann Arbor Hospital	Ann Arbor	Michigan	48106	Recruiting
University of Michigan	Ann Arbor	Michigan	48109	Active, not recruiting
Henry Ford Health Saint John Hospital	Detroit	Michigan	48236	Recruiting
Genesys Hurley Cancer Institute	Flint	Michigan	48503	Recruiting
Cancer Research Consortium of West Michigan	Grand Rapids	Michigan	49503	Recruiting
University of Michigan Health - Sparrow Lansing	Lansing	Michigan	48912	Recruiting
Trinity Health Livonia Hospital	Livonia	Michigan	48154	Recruiting
Trinity Health Oakland Hospital	Pontiac	Michigan	48341	Recruiting
MyMichigan Medical Center Saginaw	Saginaw	Michigan	48601	Recruiting
Michigan Cancer Research Consortium	Traverse City	Michigan	48341	Recruiting
Henry Ford Health Warren Hospital	Warren	Michigan	48093	Recruiting
University of Nebraska Medical Center	Omaha	Nebraska	68198	Recruiting
NH Oncology - Hematology, PA	Concord	New Hampshire	03103	Recruiting
Solinsky Center for Cancer Care	Manchester	New Hampshire	03103	Recruiting
New England Cancer Specialist	Portsmouth	New Hampshire	03801	Recruiting
Lovelace Medical Center - Saint Joseph Square	Albuquerque	New Mexico	87102	Recruiting
Presbyterian Kaseman Hospital	Albuquerque	New Mexico	87110	Recruiting
The University of New Mexico Comprehensive Cancer Center	Albuquerque	New Mexico	87131	Recruiting
Memorial Medical Center	Las Cruces	New Mexico	88011	Recruiting
Presbyterian Rust Medical Center	Rio Rancho	New Mexico	87124	Recruiting
Northwell Health Monter Cancer Center	Lake Success	New York	11042	Recruiting
Northern Westchester Hospital	Mount Kisco	New York	10549	Recruiting
Cohen Children's Medical Center	New Hyde Park	New York	11040	Recruiting
Manhattan Eye, Ear, and Throat Hospital	New York	New York	10065	Recruiting
Staten Island University Hospital	New York	New York	10305	Recruiting
Queens Cancer Center	Rego Park	New York	11374	Recruiting
Phelps Hospital	Sleepy Hollow	New York	10591	Recruiting
Lineberger Comprehensive Cancer Center	Chapel Hill	North Carolina	27599	Recruiting
Atrium Health's Levine Cancer Institute	Charlotte	North Carolina	28277	Recruiting
Sanford Health- Bismarck	Bismarck	North Dakota	58501	Recruiting
Sanford Health- Fargo	Fargo	North Dakota	58122	Recruiting
University of Cincinnati Medical Center	Cincinnati	Ohio	45219	Recruiting
Kettering Health	Kettering	Ohio	45429	Recruiting
West Chester Hospital	West Chester	Ohio	45069	Recruiting
Providence Health & Services	Portland	Oregon	97213	Recruiting
Lehigh Valley Hospital - Cedar Crest	Allentown	Pennsylvania	18103	Recruiting
Lehigh Valley Hospital- Muhlenberg	Bethlehem	Pennsylvania	18017	Recruiting
Pocono Medical Center	East Stroudsburg	Pennsylvania	18301	Recruiting
Lehigh Valley Hospital-Hazleton	Hazleton	Pennsylvania	18201	Recruiting
Fox Chase Cancer Center	Philadelphia	Pennsylvania	19111	Recruiting
SC Cancer Specialists at St. Joseph's/Candler Bluffton	Bluffton	South Carolina	29910	Recruiting
St. Joseph's/Candler Smith	Bluffton	South Carolina	29910	Recruiting
Summit Cancer Care at St. Josph's/Candler Bluffton	Bluffton	South Carolina	29910	Recruiting
South Carolina Cancer Specialists	Hilton Head Island	South Carolina	29926	Recruiting
Sanford Cancer Center Oncology Clinic and Pharmacy	Sioux Falls	South Dakota	57104	Recruiting
Tennessee Oncology - Nashville / Sarah Cannon Research Institute	Nashville	Tennessee	37203	Recruiting
The University of Texas MD Anderson Cancer Center	Houston	Texas	77030	Recruiting
Cedar City Hospital, SW Cancer Clinic, Sandra Maxwell Cancer Center	Cedar City	Utah	84720	Recruiting
Intermountain Healthcare	Salt Lake City	Utah	84107	Recruiting
Dixie Regional Medical Center-River Road Campus	St. George	Utah	84770	Recruiting
Inova Schar Cancer Institute	Fairfax	Virginia	22042	Recruiting
Northwest Medical Specialties	Bonney Lake	Washington	98391	Recruiting
Northwest Medical Specialties	Federal Way	Washington	98003	Recruiting
Northwest Medical Specialties	Gig Harbor	Washington	98332	Recruiting
Northwest Medical Specialties	Olympia	Washington	98502	Recruiting
Northwest Medical Specialties	Puyallup	Washington	98373	Recruiting
Swedish Cancer Institute	Seattle	Washington	98104	Recruiting
Northwest Medical Specialties	Tacoma	Washington	98405	Recruiting
Aurora Cancer Care - Burlington	Burlington	Wisconsin	53105	Recruiting
Aurora Health Care - Germantown Health Center	Germantown	Wisconsin	53022	Recruiting
Aurora Cancer Care - Grafton	Grafton	Wisconsin	53024	Recruiting
Aurora BayCare Medical Center	Green Bay	Wisconsin	54311	Recruiting
Aurora Cancer Care - Kenosha South	Kenosha	Wisconsin	53142	Recruiting
Aurora Bay Area Medical Center	Marinette	Wisconsin	54143	Recruiting
Aurora Cancer Care Milwaukee	Milwaukee	Wisconsin	53209	Recruiting
Aurora St. Luke's Medical Center	Milwaukee	Wisconsin	53215	Recruiting
Aurora Sinai Medical Center	Milwaukee	Wisconsin	53223	Recruiting
Aurora West Allis Medical Center	Milwaukee	Wisconsin	53227	Recruiting
Vince Lombardi Cancer Clinic - Oshkosh	Oshkosh	Wisconsin	54904	Recruiting
Aurora Cancer Care - Racine	Racine	Wisconsin	53406	Recruiting
Vince Lombardi Cancer Center	Sheboygan	Wisconsin	53081	Recruiting
Aurora Medical Center in Summit	Summit	Wisconsin	53066	Recruiting
Vince Lombardi Cancer Clinic - Two Rivers	Two Rivers	Wisconsin	54241	Recruiting
Aurora Cancer Care - Milwaukee West	Wauwatosa	Wisconsin	53226	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT02693535, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 1, 2026 · Synced May 8, 2026

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