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Terminated Phase 1 Interventional Results available

PAK4 and NAMPT in Patients With Solid Malignancies or NHL (PANAMA)

ClinicalTrials.gov ID: NCT02702492

Public ClinicalTrials.gov record NCT02702492. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 18, 2026, 5:08 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1 Open-Label Study of the Safety, Tolerability and Efficacy of KPT-9274, a Dual Inhibitor of PAK4 and NAMPT, in Patients With Advanced Solid Malignancies or Non-Hodgkin's Lymphoma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study will evaluate the safety, tolerability, and efficacy of oral KPT-9274 for the treatment of patients with advanced solid malignancies or non-Hodgkin's lymphoma (NHL).

Study identification

NCT ID
NCT02702492
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1
Lead sponsor
Karyopharm Therapeutics Inc
Industry
Enrollment
60 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 8, 2016 (Actual)
Primary completion
Jan 26, 2021 (Actual)
Completion
Jan 26, 2021 (Actual)
Last update posted
Nov 25, 2024

2016 – 2021

United States locations

U.S. sites
7
U.S. states
7
U.S. cities
7
Facility City State ZIP Site status
UCLA Health Los Angeles California 90024 —
University of Colorado Cancer Center Aurora Colorado 80045 —
Georgetown University, Lombardi Comprehensive Cancer Center Washington D.C. District of Columbia 20007 —
Mayo Clinic Rochester Rochester Minnesota 55905 —
NYU-Laura & Isaac Perlmutter Cancer Center New York New York 100016 —
Vanderbilt-Ingram Cancer Center Nashville Tennessee 37232 —
MD Anderson Cancer Center Houston Texas 77030 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02702492, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 25, 2024 · Synced Oct 18, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02702492 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →