PAK4 and NAMPT in Patients With Solid Malignancies or NHL (PANAMA)
Public ClinicalTrials.gov record NCT02702492. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1 Open-Label Study of the Safety, Tolerability and Efficacy of KPT-9274, a Dual Inhibitor of PAK4 and NAMPT, in Patients With Advanced Solid Malignancies or Non-Hodgkin's Lymphoma
Study identification
- NCT ID
- NCT02702492
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Karyopharm Therapeutics Inc
- Industry
- Enrollment
- 60 participants
Conditions and interventions
Conditions
Interventions
- KPT-9274 Drug
- Niacin ER Drug
- Nivolumab Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 7, 2016
- Primary completion
- Jan 25, 2021
- Completion
- Jan 25, 2021
- Last update posted
- Nov 24, 2024
2016 – 2021
United States locations
- U.S. sites
- 7
- U.S. states
- 7
- U.S. cities
- 7
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UCLA Health | Los Angeles | California | 90024 | — |
| University of Colorado Cancer Center | Aurora | Colorado | 80045 | — |
| Georgetown University, Lombardi Comprehensive Cancer Center | Washington D.C. | District of Columbia | 20007 | — |
| Mayo Clinic Rochester | Rochester | Minnesota | 55905 | — |
| NYU-Laura & Isaac Perlmutter Cancer Center | New York | New York | 100016 | — |
| Vanderbilt-Ingram Cancer Center | Nashville | Tennessee | 37232 | — |
| MD Anderson Cancer Center | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02702492, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 24, 2024 · Synced Apr 29, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02702492 live on ClinicalTrials.gov.