A Dose Frequency Optimization,Trial of Nivolumab 240 mg Every 2 Weeks vs Nivolumab 480 mg Every 4 Weeks in Subjects With Advanced or Metastatic Non-small Cell Lung Cancer Who Received Up to 12 Months of Nivolumab at 3 mg/kg or 240 mg Every 2 Weeks
Public ClinicalTrials.gov record NCT02713867. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Dose Frequency Optimization, Phase IIIB/IV Trial of Nivolumab 240 mg Every 2 Weeks vs Nivolumab 480 mg Every 4 Weeks in Subjects With Advanced or Metastatic Non-small Cell Lung Cancer Who Received up to 12 Months of Nivolumab at 3 mg/kg or 240 mg Every 2 Weeks
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of this study is to compare PFS (progression-free survival) rate at 6 months and at 1 year after randomization, of Nivolumab 480 mg every 4 weeks with nivolumab 240 mg every 2 weeks in subjects with advanced/metastatic (Stage IIIb/IV) NSCLC (non-Sq and Sq).
Study identification
- NCT ID
- NCT02713867
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 363 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 23, 2016
- Primary completion
- Jul 14, 2019
- Completion
- Jan 17, 2022
- Last update posted
- Feb 13, 2023
2016 – 2022
United States locations
- U.S. sites
- 77
- U.S. states
- 31
- U.S. cities
- 73
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Local Institution - 0004 | Birmingham | Alabama | 35205 | — |
| Local Institution - 0030 | Phoenix | Arizona | 85016 | — |
| Local Institution - 0041 | Phoenix | Arizona | 85016 | — |
| CBCC Global Research, Inc. | Bakersfield | California | 93309 | — |
| Southern California Permanente Medical Group | Bellflower | California | 90706 | — |
| St Jude Hospital Yorba Linda | Fullerton | California | 92835 | — |
| Local Institution - 0046 | Los Angeles | California | 90095 | — |
| Local Institution - 0126 | Orange | California | 92868 | — |
| Torrance Health Association | Redondo Beach | California | 90227 | — |
| Sharp Memorial Hospital | San Diego | California | 92123 | — |
| Local Institution - 0010 | Santa Barbara | California | 93015 | — |
| Local Institution - 0044 | Santa Maria | California | 93454 | — |
| Local Institution - 0130 | Vallejo | California | 94589 | — |
| Local Institution - 0017 | Denver | Colorado | 80218-1210 | — |
| Local Institution - 0122 | Fort Collins | Colorado | 80528 | — |
| Local Institution - 0038 | Fort Myers | Florida | 33901 | — |
| Local Institution - 0089 | Hollywood | Florida | 33021 | — |
| Local Institution - 0026 | Ocala | Florida | 34471 | — |
| Local Institution - 0001 | Pensacola | Florida | 32504 | — |
| Local Institution - 0039 | St. Petersburg | Florida | 33705 | — |
| Local Institution - 0008 | Athens | Georgia | 30607 | — |
| Local Institution - 0142 | Columbus | Georgia | 31904 | — |
| Local Institution - 0121 | Marietta | Georgia | 30060 | — |
| Ingalls Health System | Harvey | Illinois | 60426 | — |
| Local Institution - 0098 | Niles | Illinois | 60714 | — |
| Local Institution - 0100 | Peoria | Illinois | 61615 | — |
| Local Institution - 0143 | Urbana | Illinois | 61801-2594 | — |
| Local Institution - 0099 | Fort Wayne | Indiana | 46485 | — |
| Local Institution - 0050 | Fort Wayne | Indiana | 46804 | — |
| Innova Schar Cancer Institute | Indianapolis | Indiana | 46237 | — |
| Local Institution - 0123 | Wichita | Kansas | 67214 | — |
| Local Institution - 0112 | Paducah | Kentucky | 42003 | — |
| Mary Bird Perkins Cancer Center | Baton Rouge | Louisiana | 70809 | — |
| Local Institution - 0137 | New Orleans | Louisiana | 70121 | — |
| Local Institution - 0109 | Brewer | Maine | 04412 | — |
| Local Institution - 0042 | Bethesda | Maryland | 20817 | — |
| Local Institution - 0125 | Springfield | Massachusetts | 01107 | — |
| Local Institution - 0136 | Southfield | Michigan | 48075 | — |
| Local Institution - 0120 | Minneapolis | Minnesota | 55404 | — |
| Local Institution - 0116 | Tupelo | Mississippi | 38801 | — |
| Mercy Medical Research Institute | Springfield | Missouri | 65806 | — |
| Local Institution - 0014 | Omaha | Nebraska | 68130 | — |
| Local Institution - 0141 | Lebanon | New Hampshire | 03756 | — |
| Local Institution - 0035 | Albany | New York | 12206 | — |
| Local Institution - 0013 | Johnson City | New York | 13790 | — |
| Local Institution - 0127 | Pinehurst | North Carolina | 28374 | — |
| Hematology And Oncology Associates | Canton | Ohio | 44708 | — |
| Local Institution - 0037 | Cincinnati | Ohio | 45242 | — |
| Local Institution - 0132 | Cincinnati | Ohio | 45242 | — |
| MetroHealth Cancer Care Center | Cleveland | Ohio | 44109 | — |
| Local Institution - 0129 | Massillon | Ohio | 44646 | — |
| Hematology Oncology Consultants, Pc | Medford | Oregon | 97504 | — |
| Local Institution - 0005 | Pittsburgh | Pennsylvania | 15224 | — |
| Local Institution - 0020 | Charleston | South Carolina | 29414 | — |
| Local Institution - 0124 | Sioux Falls | South Dakota | 57105 | — |
| Jones Clinic PC | Germantown | Tennessee | 38138 | — |
| Local Institution - 0036 | Nashville | Tennessee | 37203 | — |
| Local Institution - 0023 | Abilene | Texas | 79606-5208 | — |
| Texas Oncology - Amarillo | Amarillo | Texas | 79106 | — |
| Local Institution - 0011 | Dallas | Texas | 75230 | — |
| Local Institution - 0022 | Dallas | Texas | 75231 | — |
| Texas Oncology, P.A. | Denton | Texas | 76210 | — |
| Texas Oncology, P.A. | El Paso | Texas | 79902 | — |
| Local Institution - 0025 | Flower Mound | Texas | 75028 | — |
| Texas Oncology, P.A. | Houston | Texas | 77024 | — |
| Texas Oncology, P.A. | Longview | Texas | 75601 | — |
| Local Institution - 0119 | Midland | Texas | 79701 | — |
| Texas Oncology, P.A. | Plano | Texas | 75093 | — |
| Texas Oncology, P.A. | San Antonio | Texas | 78212 | — |
| Texas Oncology, P.A. | Sherman | Texas | 75090 | — |
| Texas Oncology, P.A. | Sugar Land | Texas | 77479 | — |
| Local Institution - 0034 | Wichita Falls | Texas | 76310 | — |
| Innova Schar Cancer Institute | Falls Church | Virginia | 22042 | — |
| Shenandoah Oncology | Winchester | Virginia | 22601 | — |
| Cancer Care Northwest | Spokane Valley | Washington | 99216 | — |
| Local Institution - 0031 | Vancouver | Washington | 98684 | — |
| Yakima Valley Memorial Hospital/North Star Lodge | Yakima | Washington | 98902 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 52 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02713867, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 13, 2023 · Synced Sep 27, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02713867 live on ClinicalTrials.gov.