ClinicalTrials.gov record
Avelumab in Previously Untreated Patients With Epithelial Ovarian Cancer (JAVELIN OVARIAN 100)
ClinicalTrials.gov ID: NCT02718417
Public ClinicalTrials.gov record NCT02718417. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A RANDOMIZED, OPEN-LABEL, MULTICENTER, PHASE 3 STUDY TO EVALUATE THE EFFICACY AND SAFETY OF AVELUMAB (MSB0010718C) IN COMBINATION WITH AND/OR FOLLOWING CHEMOTHERAPY IN PATIENTS WITH PREVIOUSLY UNTREATED EPITHELIAL OVARIAN CANCER JAVELIN OVARIAN 100
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase 3, open-label, international, multi-center, efficacy, and safety study of avelumab in combination with and/or following platinum-based chemotherapy. Eligible patients must have previously untreated, histologically confirmed Stage III-IV epithelial ovarian (EOC), fallopian tube cancer (FTC), or primary peritoneal cancer (PPC) and be candidates for platinum-based chemotherapy. The primary purpose of the study is to demonstrate if avelumab given as single agent in the maintenance setting following frontline chemotherapy or in combination with carboplatin/paclitaxel is superior to platinum-based chemotherapy alone followed by observation in this population of newly diagnosed ovarian cancer patients.
Study identification
- NCT ID
- NCT02718417
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 998 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 18, 2016
- Primary completion
- Sep 6, 2018
- Completion
- May 15, 2019
- Last update posted
- Jul 13, 2020
2016 – 2019
United States locations
- U.S. sites
- 146
- U.S. states
- 22
- U.S. cities
- 73
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alabama Oncology | Alabaster | Alabama | 35007 | — |
| Alabama Oncology | Bessemer | Alabama | 35022 | — |
| Alabama Oncology, Bruno Cancer Center | Birmingham | Alabama | 35205 | — |
| Alabama Oncology | Birmingham | Alabama | 35209 | — |
| Alabama Oncology | Birmingham | Alabama | 35211 | — |
| Alabama Oncology | Birmingham | Alabama | 35235 | — |
| Alabama Oncology | Birmingham | Alabama | 35243 | — |
| Arizona Oncology Associates, PC - HAL | Phoenix | Arizona | 85016 | — |
| Arizona Oncology Associates, PC - HAL | Phoenix | Arizona | 85027 | — |
| Arizona Oncology Associates, PC - HAL | Scottsdale | Arizona | 85258 | — |
| Arizona Oncology Associates, PC - HAL | Tempe | Arizona | 85284 | — |
| Arizona Oncology Associates, PC-HOPE | Tucson | Arizona | 85704 | — |
| Arizona Oncology Associates, PC-HOPE | Tucson | Arizona | 85711 | — |
| Highlands Oncology Group | Fayetteville | Arkansas | 72703 | — |
| Highlands Oncology Group | Rogers | Arkansas | 72758 | — |
| Oso HomeCare | Irvine | California | 92614 | — |
| Cedars-Sinai Medical Center, Samuel Oschin Comprehensive Cancer Institute | Los Angeles | California | 90048 | — |
| Medical Center, Cedars-Sinai | Los Angeles | California | 90048 | — |
| Gynecologic Oncology Associates | Newport Beach | California | 92663 | — |
| Chao Family Comprehensive Cancer Center | Orange | California | 92868 | — |
| Hematology-Oncology Medical Group of Orange County | Orange | California | 92868 | — |
| Medical Oncology Care Associates | Orange | California | 92868 | — |
| St. Joseph Hospital of Orange | Orange | California | 92868 | — |
| The Center for Cancer Prevention and Treatment at St. Joseph Hospital of Orange | Orange | California | 92868 | — |
| UC Irvine Health | Orange | California | 92868 | — |
| University of California, Irvine/UC Irvine Health | Orange | California | 92868 | — |
| California Pacific Medical Center - Medical Office Building | San Francisco | California | 94109 | — |
| California Pacific Medical Center - Van Ness Campus | San Francisco | California | 94109 | — |
| California Pacific Medical Center - Davies Campus | San Francisco | California | 94114 | — |
| Bryan Hemming Cancer Care Center - California Pacific Medical Center | San Francisco | California | 94115 | — |
| California Pacific Medical Center - Pacific Heights Outpatient Pharmacy | San Francisco | California | 94115 | — |
| California Pacific Medical Center-Pacific Campus | San Francisco | California | 94115 | — |
| California Pacific Medical Center-Research Institute | San Francisco | California | 94115 | — |
| Palo Alto Medical Foundation Group | San Francisco | California | 94118 | — |
| Sansum Clinic | Santa Barbara | California | 93105 | — |
| Sansum Clinic | Solvang | California | 93463 | — |
| Rocky Mountain Cancer Centers | Aurora | Colorado | 80012 | — |
| Rocky Mountain Cancer Centers | Boulder | Colorado | 80303 | — |
| Rocky Mountain Cancer Centers | Lakewood | Colorado | 80228 | — |
| C/O Thomas Ferencz, RPh, BCOP, Smilow Cancer Hospital at Yale-New Haven | New Haven | Connecticut | 06510 | — |
| Smilow Cancer Hospital at Yale-New Haven | New Haven | Connecticut | 06510 | — |
| Smilow Cancer Hospital at Yale-New Haven | New Haven | Connecticut | 06520 | — |
| Johns Hopkins Sibley Memorial Hospital | Washington D.C. | District of Columbia | 20016 | — |
| Sibley Memorial Hospital | Washington D.C. | District of Columbia | 20016 | — |
| UHEALTH Deerfield Beach | Deerfield Beach | Florida | 33442 | — |
| University of Miami Hospital and Clinics | Miami | Florida | 33136 | — |
| Orlando Health Gynecological Cancer Center | Orlando | Florida | 32806 | — |
| Orlando Health UF Health Cancer Center | Orlando | Florida | 32806 | — |
| Orlando Health, Inc. | Orlando | Florida | 32806 | — |
| Orlando Health, Inc | Orlando | Florida | 32806 | — |
| Emory University Hospital Midtown | Atlanta | Georgia | 30308 | — |
| Emory University Hospital | Atlanta | Georgia | 30322 | — |
| Investigational Drug Service, Emory University Clinic | Atlanta | Georgia | 30322 | — |
| The Emory Clinic | Atlanta | Georgia | 30322 | — |
| Winship Cancer Institute | Atlanta | Georgia | 30322 | — |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University | Baltimore | Maryland | 21287 | — |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Baltimore | Maryland | 21287 | — |
| Rcca Md Llc | Bethesda | Maryland | 20817 | — |
| Rcca Md Llc | Germantown | Maryland | 20874 | — |
| SKCCC at Johns Hopkins, Green Spring Station | Lutherville | Maryland | 21093 | — |
| Women's Health Specialists of Montgomery County | Rockville | Maryland | 20852 | — |
| Holy Cross Resource Center | Silver Spring | Maryland | 20902 | — |
| Maryland Oncology Hematology | Silver Spring | Maryland | 20904 | — |
| Holy Cross Hospital, Pharmacy | Silver Spring | Maryland | 20910 | — |
| Holy Cross Hospital | Silver Spring | Maryland | 20910 | — |
| Maryland Oncology Hematology | Wheaton | Maryland | 20902 | — |
| Massachusetts General Hospital Attn: Svetlana Rashkova, RPh | Boston | Massachusetts | 02114 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Brigham & Women's Hospital | Boston | Massachusetts | 02115 | — |
| Beth Israel Deaconess Medical Center Attn: Nisha Sharma | Boston | Massachusetts | 02215 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Dana Farber Cancer Institute Attn: Vasilika Koci, PharmD | Boston | Massachusetts | 02215 | — |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | — |
| Mercy Ministry Office | Chesterfield | Missouri | 63017 | — |
| Mercy - Women's Oncology | Springfield | Missouri | 65804 | — |
| Mercy Clinic Cancer and Hematology - Chub O'Reilly Cancer Center | Springfield | Missouri | 65804 | — |
| Mercy Hospital Springfield | Springfield | Missouri | 65804 | — |
| Summit Medical Group | Berkeley Heights | New Jersey | 07922 | — |
| Summit Medical Group PA | Florham Park | New Jersey | 07932 | — |
| University Hospital, Investigational Drug Pharmacy | Newark | New Jersey | 07103-6750 | — |
| University Hospital | Newark | New Jersey | 07103-6750 | — |
| University Hospital, Ambulatory Care Center | Newark | New Jersey | 07103 | — |
| University Hospital, The Cancer Center | Newark | New Jersey | 07103 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | — |
| Medical Arts Radiology | Huntington | New York | 11743 | — |
| ProHealth Radiology | Huntington | New York | 11743 | — |
| NYU Winthrop Hospital, Clinical Trials Center | Mineola | New York | 11501 | — |
| NYU Winthrop Hospital, Gynecologic Oncology | Mineola | New York | 11501 | — |
| NYU Winthrop Hospital, Infusion Center | Mineola | New York | 11501 | — |
| NYU Winthrop Hospital, Research Pharmacy | Mineola | New York | 11501 | — |
| NYU Winthrop Radiology | Mineola | New York | 11501 | — |
| Montefiore - Einstein Center for Cancer Care | The Bronx | New York | 10461 | — |
| Montefiore Medical Center | The Bronx | New York | 10461 | — |
| Montefiore Medical Center, Centennial Women's Center | The Bronx | New York | 10467 | — |
| Oncology Hematology Care, Inc. | Cincinnati | Ohio | 45211 | — |
| Oncology Hematology Care, Inc. | Cincinnati | Ohio | 45236 | — |
| Oncology Hematology Care, Inc. | Cincinnati | Ohio | 45242 | — |
| Oncology Hematology Care, Inc. | Cincinnati | Ohio | 45245 | — |
| MetroHealth Medical Center | Cleveland | Ohio | 44106 | — |
| MetroHealth Medical Center | Cleveland | Ohio | 44109 | — |
| OSU Wexner Medical Center, Arthur G. James Cancer Hospital & Solove Research Institute | Columbus | Ohio | 43210 | — |
| OSU Wexner Medical Center, Investigational Drug Services | Columbus | Ohio | 43210 | — |
| OSU Wexner Medical Center, Stefanie Spielman Comprehensive Breast Center | Columbus | Ohio | 43212 | — |
| Oncology Hematology Care, Inc. | Fairfield | Ohio | 45014 | — |
| OSU Wexner Medical Center, Gynecologic Oncology at Mill Run | Hilliard | Ohio | 43026 | — |
| Willamette Valley Cancer Institute and Research Center | Eugene | Oregon | 97401 | — |
| Asante Three Rivers Medical Center | Grants Pass | Oregon | 97527 | — |
| Hematology Oncology Associates | Grants Pass | Oregon | 97527 | — |
| Asante Pharmacy | Medford | Oregon | 97501 | — |
| Asante Rogue Regional Medical Center | Medford | Oregon | 97504 | — |
| Hematology Oncology Associates | Medford | Oregon | 97504 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| Magee-Women's Hospital of UPMC | Pittsburgh | Pennsylvania | 15213 | — |
| University of Pittsburgh Cancer Institute Investigational Drug Service | Pittsburgh | Pennsylvania | 15232 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15232 | — |
| Avera Cancer Institute | Sioux Falls | South Dakota | 57105 | — |
| Tennessee Oncology, PLLC | Dickson | Tennessee | 37055 | — |
| Tennessee Oncology, PLLC | Franklin | Tennessee | 37067 | — |
| Tennessee Oncology, PLLC | Gallatin | Tennessee | 37066 | — |
| Tennessee Oncology, PLLC | Hermitage | Tennessee | 37076 | — |
| Tennessee Oncology, PLLC | Lebanon | Tennessee | 37090 | — |
| Tennessee Oncology, PLLC | Murfreesboro | Tennessee | 37129 | — |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37203 | — |
| The Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | — |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37205 | — |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37207 | — |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37211 | — |
| Tennessee Oncology, PLLC | Shelbyville | Tennessee | 37160 | — |
| Tennessee Oncology, PLLC | Smyrna | Tennessee | 37167 | — |
| Texas Oncology-Austin Central | Austin | Texas | 78731 | — |
| Texas Oncology - South Austin | Austin | Texas | 78745 | — |
| Texas Oncology Bedford | Bedford | Texas | 76022 | — |
| Parkland Health and Hospital System | Dallas | Texas | 75235 | — |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | — |
| UT Southwestern Medical Center-Clements University Hospital | Dallas | Texas | 75390 | — |
| UT Southwestern Medical Center-Zale Lipshy University Hospital | Dallas | Texas | 75390 | — |
| Texas Oncology - Fort Worth Cancer Center | Fort Worth | Texas | 76104 | — |
| US Oncology Investigational Products Center (IPC) | Irving | Texas | 75063 | — |
| US Oncology Investigational Products Center | Irving | Texas | 75063 | — |
| Texas Oncology - San Antonio Medical Center | San Antonio | Texas | 78240 | — |
| Utah Cancer Specialists | Layton | Utah | 84041 | — |
| Utah Cancer Specialists | Murray | Utah | 84157 | — |
| Utah Cancer Specialists | Salt Lake City | Utah | 84102 | — |
| Utah Cancer Specialists | Salt Lake City | Utah | 84106 | — |
| Utah Cancer Specialists | West Jordan | Utah | 84088 | — |
| Emily Couric Cancer Center | Charlottesville | Virginia | 22903 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 173 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02718417, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 13, 2020 · Synced Sep 3, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02718417 live on ClinicalTrials.gov.