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Completed Phase 2 Interventional Results available

A Study of Sapanisertib, Combination of Sapanisertib With MLN1117, Paclitaxel and Combination of Sapanisertib With Paclitaxel in Women With Endometrial Cancer

ClinicalTrials.gov ID: NCT02725268

Public ClinicalTrials.gov record NCT02725268. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 24, 2026, 4:45 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Randomized Study of MLN0128 (a Dual TORC1/2 Inhibitor), MLN0128+MLN1117 (a PI3Kα Inhibitor), Weekly Paclitaxel, or the Combination of Weekly Paclitaxel and MLN0128 in Women With Advanced, Recurrent, or Persistent Endometrial Cancer

Study identification

NCT ID
NCT02725268
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Millennium Pharmaceuticals, Inc.
Industry
Enrollment
241 participants

Conditions and interventions

Interventions

  • Paclitaxel Drug
  • Sapanisertib Drug
  • MLN1117 Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
Female
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 2016
Primary completion
Jul 1, 2019
Completion
Oct 29, 2020
Last update posted
Nov 23, 2021

2016 – 2020

United States locations

U.S. sites
21
U.S. states
15
U.S. cities
20
Facility City State ZIP Site status
University of Alabama Comprehensive Cancer Center Birmingham Alabama 35294-3300
University of Arizona Cancer Center Phoenix Arizona 85013
Marin Cancer Care Greenbrae California 94904
University of California San Diego Medical Center La Jolla California 92093-1503
University of California at San Francisco (PARENT) San Francisco California 94115
Stanford School of Medicine Stanford California 94305
H. Lee Moffitt Cancer Center and Research Institute, Inc Tampa Florida 33612-9416
Florida Cancer Specialists West Palm Beach Florida 33401
Augusta University Augusta Georgia 30912
Franciscan St. Francis Health Indianapolis Indiana 46237
University of Kansas Medical Center Research Institute, Inc. Westwood Kansas 66205
Massachusetts General Hospital Cancer Center Boston Massachusetts 02114
Washington University St Louis Missouri 63108
NYU Langone Medical Center Clinic New York New York 10016
Memorial Sloan Kettering Cancer Center New York New York 10065-6094
Levine Cancer Institute Charlotte North Carolina 28204
Oklahoma University Health Sciences Center Oklahoma City Oklahoma 73104
Fox Chase Cancer Center Philadelphia Pennsylvania 19111
University of Pittsburgh Medical Center Cancer Center at Magee-Womens Hospital Pittsburgh Pennsylvania 15232
Sarah Cannon Research Institute Nashville Tennessee 37203
University of Texas Southwestern Medical Center Dallas Texas 75390

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 57 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02725268, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 23, 2021 · Synced Jul 24, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02725268 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →