Clinical Study of Pulsed, Inhaled Nitric Oxide Versus Placebo in Symptomatic Subjects With PAH
Public ClinicalTrials.gov record NCT02725372. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Placebo Controlled, Double-Blind, Randomized, Clinical Study to Determine Efficacy, Safety, and Tolerability of Pulsed, Inhaled Nitric Oxide (iNO) Versus Placebo in Symptomatic Subjects With PAH (Part 1 and Part 2)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Phase 3, placebo controlled, double-blind, randomized clinical study to determine safety, tolerability, and efficacy of pulsed, inhaled nitric oxide (iNO) versus placebo in symptomatic subjects with pulmonary arterial hypertension (PAH). Part 1 and Part 2
Study identification
- NCT ID
- NCT02725372
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 207 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2016 (Actual)
- Primary completion
- Aug 2018 (Actual)
- Completion
- Aug 2018 (Actual)
- Last update posted
- Feb 21, 2023
2016 – 2018
United States locations
- U.S. sites
- 37
- U.S. states
- 18
- U.S. cities
- 36
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Pulmonary Specialists, Ltd | Phoenix | Arizona | 85012 | — |
| University of Arizona Sarver Heart Center | Tucson | Arizona | 85724-5046 | — |
| Cedars-Sinai Medical Center | Beverly Hills | California | 90211 | — |
| UC San Diego / Pulmonary, Critical Care and Sleep Medicine Division | La Jolla | California | 92093 | — |
| West Los Angeles VA Healthcare Center | Los Angeles | California | 90073 | — |
| University of California, Davis Medical Center | Sacramento | California | 95817 | — |
| University of Colorado Denver | Aurora | Colorado | 80045 | — |
| Pulmonary Disease Specialists, PA | Kissimmee | Florida | 34741 | — |
| Central Florida Pulmonary Group, PA | Orlando | Florida | 32803-5727 | — |
| Cleveland Clinic Florida | Weston | Florida | 33331 | — |
| Pulmonary and Critical Care of Atlanta | Atlanta | Georgia | 30342 | — |
| Piedmont Healthcare Pulmonary and Critical Care Research | Austell | Georgia | 30106 | — |
| Wellstar Medical Group - Pulmonary Medicine | Marietta | Georgia | 30060 | — |
| Bluhm Cardiovascular Institute, Clinical Trials Unit | Chicago | Illinois | 60611 | — |
| HeartCare Midwest | Peoria | Illinois | 61616 | — |
| Kentuckiana Pulmonary Associates (KPA), Inc. - Louisville | Louisville | Kentucky | 40202-1332 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198-5590 | — |
| Albany Medical Center | Albany | New York | 12208 | — |
| New York Presbyterian Brooklyn Methodist Hospital - Division of Pulmonary/Critical Care/Sleep | Brooklyn | New York | 11215 | — |
| Winthrop University Hospital, Clinical Trials Center | Mineola | New York | 11501 | — |
| NYU Medical Center, Division Pulmonary, Critical Care and Sleep Medicine | New York | New York | 10279 | — |
| Montefiore Medical Center - Weiler Division | The Bronx | New York | 10461 | — |
| University of Cincinnati Medical Ctr, Dept of Internal Medicine / Pulmonary, Critical Care & Sleep Medicine | Cincinnati | Ohio | 45267-0564 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| The Ohio State University | Columbus | Ohio | 43065 | — |
| Legacy Medical Group - Pulmonary Clinic | Portland | Oregon | 97210 | — |
| The Oregon Clinic, PC | Portland | Oregon | 97220 | — |
| Temple University Hospital | Philadelphia | Pennsylvania | 19140 | — |
| Allegheny Singer Research Institute | Pittsburgh | Pennsylvania | 15212 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| MedTrial, LLC | Columbia | South Carolina | 29204 | — |
| Sioux Falls Cardiovascular | Sioux Falls | South Dakota | 57108 | — |
| University of Texas Southwestern Medical Center of Dallas | Dallas | Texas | 75390-8550 | — |
| Pulmonary Associates of Richmond | Richmond | Virginia | 23229 | — |
| University of Wisconsin | Madison | Wisconsin | 53792-1615 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 72 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02725372, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 21, 2023 · Synced Oct 18, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02725372 live on ClinicalTrials.gov.