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Completed Phase 2 Interventional

A Multiple Dose, Dose Escalation Trial of AEB1102 in Patients With AML or MDS

ClinicalTrials.gov ID: NCT02732184

Public ClinicalTrials.gov record NCT02732184. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 23, 2026, 10:54 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Dose-Escalation Study of AEB1102 (Co-ArgI-PEG) in Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome Refractory to Hypomethylating Agents

Study identification

NCT ID
NCT02732184
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Aeglea Biotherapeutics
Industry
Enrollment
29 participants

Conditions and interventions

Interventions

  • Co-ArgI-PEG modified human arginase I Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 90 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 31, 2016
Primary completion
Nov 30, 2017
Completion
Nov 30, 2017
Last update posted
Oct 16, 2018

2016 – 2017

United States locations

U.S. sites
7
U.S. states
5
U.S. cities
5
Facility City State ZIP Site status
Comprehensive Cancer Center at University of Michigan Ann Arbor Michigan 48109
Washington University Medical School St Louis Missouri 63110
University Hospitals Case Medical Center Cleveland Ohio 44106
The Cleveland Clinic Cleveland Ohio 44195
Vanderbilt-Ingram Cancer Center Nashville Tennessee 37232
Baylor Scott & White Dallas Texas 75246
University of Texas Southwestern Medical Center Dallas Texas 75390

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02732184, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 16, 2018 · Synced Jul 23, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02732184 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →