ClinicalTrials.gov record

Completed Not applicable Interventional Accepts healthy volunteers Results available

Intranasal Oxytocin and Maternal Neglect

ClinicalTrials.gov ID: NCT02737436

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Official title

Intranasal Oxytocin: A Neuropharmacological Intervention for Maternal Neglect?

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The investigators plan to conduct functional MRI scanning with a group of mothers who are blindly and randomly assigned either intranasal oxytocin or a placebo. The purpose of this investigation is to explore how oxytocin may modify early maternal brain and behavioral responses to infant cues. This study will examine, for the first time, a potential pharmacological intervention for maternal neglect which targets core neurobiological deficits. This may eventually be used to supplement and augment other psychosocial and behavioral interventions. In addition, the investigators will examine sex differences in parental brain and behavioral responses to oxytocin by also recruiting fathers to participate in a similar protocol.

Study identification

NCT ID: NCT02737436
Recruitment status: Completed
Study type: Interventional
Phase: Not applicable
Lead sponsor: Baylor College of Medicine; Other
Enrollment: 132 participants

Conditions and interventions

Conditions

Maternal Behavior

Interventions

Drug · Procedure

Eligibility (public fields only)

Age range: 20 Years to 45 Years
Sex: All
Healthy volunteers: Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: May 2010 (Type not available)
Primary completion: Mar 2019 (Actual)
Completion: Mar 2019 (Actual)
Last update posted: Jan 28, 2025

2010 – 2019

United States locations

U.S. sites: 2
U.S. states: 2
U.S. cities: 2

Facility	City	State	ZIP	Site status
University of Iowa	Iowa City	Iowa	52242	—
Children's Nutrition Research Center	Houston	Texas	77030	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT02737436, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Jan 28, 2025 · Synced Nov 15, 2026