Long-term Safety and Efficacy Study of DX-2930 (SHP643) to Prevent Acute Angioedema Attacks in Patients With Type I and Type II HAE
Public ClinicalTrials.gov record NCT02741596. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
HELP Study ExtensionTM: An Open-Label Study to Evaluate the Long-Term Safety and Efficacy of DX-2930 for Prevention Against Acute Attacks of Hereditary Angioedema (HAE)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is an open-label, long term safety and efficacy study to evaluate DX-2930 in preventing acute angioedema attacks in participants with Type I and Type II HAE.
Study identification
- NCT ID
- NCT02741596
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 212 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 26, 2016 (Actual)
- Primary completion
- Oct 31, 2019 (Actual)
- Completion
- Oct 31, 2019 (Actual)
- Last update posted
- Jun 8, 2021
2016 – 2019
United States locations
- U.S. sites
- 31
- U.S. states
- 21
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinical Research Center of Alabama | Birmingham | Alabama | 35209 | — |
| Medical Research of Arizona | Scottsdale | Arizona | 85251 | — |
| University of California San Diego | San Diego | California | 92122 | — |
| AIRE Medical of Los Angeles | Santa Monica | California | 90404 | — |
| Allergy & Asthma Clinical Research | Walnut Creek | California | 94598 | — |
| IMMUNOe Research Centers | Centennial | Colorado | 80112 | — |
| Asthma and Allergy Associates, PC | Colorado Springs | Colorado | 80907 | — |
| University of South Florida | Tampa | Florida | 33613 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Institute Asthma and Allergy | Chevy Chase | Maryland | 20815 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02421 | — |
| University of Michigan | Ann Arbor | Michigan | 48106 | — |
| Midwest Immunology Clinic | Plymouth | Minnesota | 55446 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Hudson-Essex Allergy, LLC | Belleville | New Jersey | 07109 | — |
| Atlantic Research Center, LLC | Ocean City | New Jersey | 07712 | — |
| Winthrop University Hospital | Mineola | New York | 11501 | — |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | — |
| Clinical Research Center of Charlotte | Charlotte | North Carolina | 28277 | — |
| Duke Asthma, Allergy, and Airway Center | Durham | North Carolina | 27705 | — |
| Bernstein Clinical Research Center, LLC | Cincinnati | Ohio | 45231 | — |
| Optimed Research, LTD. | Columbus | Ohio | 43235 | — |
| Toledo Institute of Clinical REsearch | Toledo | Ohio | 43617 | — |
| Penn State Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| Austin Regional Clinic | Austin | Texas | 78731 | — |
| AARA Research Center | Dallas | Texas | 75231 | — |
| Intermountain Clinical Research | Draper | Utah | 84020 | — |
| Allergy Associates of Utah | Murray | Utah | 84107 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23219 | — |
| Premier Clinical Research | Spokane | Washington | 99202 | — |
| Medical College of Wisconsin, Childrens Hospital | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 12 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02741596, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 8, 2021 · Synced Nov 1, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02741596 live on ClinicalTrials.gov.