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Completed Phase 2 Interventional Results available

Inorganic Nitrite Delivery to Improve Exercise Capacity in HFpEF

ClinicalTrials.gov ID: NCT02742129

Public ClinicalTrials.gov record NCT02742129. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 22, 2026, 8:05 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

A randomized, double-blind, placebo-controlled crossover study to assess the effect of inorganic nitrite (NO2) on aerobic capacity (peak VO2) after four weeks of dosing. Approximately 100 participants will be enrolled in this 2\*2 crossover study.

Study identification

NCT ID
NCT02742129
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Adrian Hernandez
Other
Enrollment
105 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
40 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 10, 2016 (Actual)
Primary completion
Dec 13, 2017 (Actual)
Completion
Dec 27, 2017 (Actual)
Last update posted
Mar 13, 2019

2016 – 2017

United States locations

U.S. sites
20
U.S. states
11
U.S. cities
14
Facility City State ZIP Site status
Emory University School of Medicine Atlanta Georgia 30322 —
Northwestern University Chicago Illinois 60611 —
Johns Hopkins Hospital Baltimore Maryland 21287 —
Tufts Medical Center Boston Massachusetts 02111 —
Massachusetts General Hospital Boston Massachusetts 02114 —
Brigham and Women's Hospital Boston Massachusetts 02115 —
Boston V.A. Healthcare System West Roxbury Massachusetts 02132 —
Mayo Clinic Rochester Minnesota 55905 —
University of Missouri Health System Columbia Missouri 65212 —
V.A St. Louis Health Care System St Louis Missouri 63106 —
Washington University School of Medicine St Louis Missouri 63110 —
Stony Brook University Medical Center Stony Brook New York 11794 —
Duke University Medical Center Durham North Carolina 27705 —
University Hospitals Cleveland Medical Center Cleveland Ohio 44106 —
Metro Health System Cleveland Ohio 44109 —
Cleveland Clinic Foundation Cleveland Ohio 44195 —
Abington Memorial Hospital Abington Pennsylvania 19001 —
University of Pennsylvania Health System Philadelphia Pennsylvania 19104 —
Jefferson Medical College Philadelphia Pennsylvania 19107 —
The University of Vermont - Fletcher Allen Health Care Burlington Vermont 05401 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02742129, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 13, 2019 · Synced Oct 22, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02742129 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →