ClinicalTrials.gov record
Long-Term Safety of Lampalizumab Intravitreal (ITV) Injections in Participants With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (OMASPECT)
ClinicalTrials.gov ID: NCT02745119
Public ClinicalTrials.gov record NCT02745119. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Open-Label Extension Study to Evaluate the Long-Term Safety and Tolerability of Lampalizumab in Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration Who Have Completed a Roche-Sponsored Study
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This multicenter open-label extension study is designed to evaluate the safety and tolerability of lampalizumab intravitreal injections in participants with GA secondary to age-related macular degeneration (AMD) who completed 96 weeks of treatment in Studies GX29176 (NCT02247479) or GX29185 (NCT02247531). The extension will enroll participants from the parent studies who received investigational lampalizumab, as well as lampalizumab-naive participants exposed to sham comparator. All participants will receive open-label lampalizumab in the present study.
Study identification
- NCT ID
- NCT02745119
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 994 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 21, 2016 (Actual)
- Primary completion
- Jan 31, 2018 (Actual)
- Completion
- Jan 31, 2018 (Actual)
- Last update posted
- Mar 6, 2019
2016 – 2018
United States locations
- U.S. sites
- 122
- U.S. states
- 34
- U.S. cities
- 106
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Uni of Alabama At Birmingham Clinical Research Unit | Birmingham | Alabama | 35233 | — |
| Retinal Research Institute, LLC | Phoenix | Arizona | 85014 | — |
| Associated Retina Consultants | Phoenix | Arizona | 85020 | — |
| Retina Centers P.C. | Tucson | Arizona | 85704 | — |
| Retina Associates Southwest PC | Tucson | Arizona | 85750 | — |
| California Retina Consultants | Bakersfield | California | 93309 | — |
| Retina-Vitreous Associates Medical Group | Beverly Hills | California | 90211 | — |
| Retina Consultants of Orange County | Fullerton | California | 92835 | — |
| UCSD Shiley Eye Center | La Jolla | California | 92093-0946 | — |
| Jules Stein Eye Institute/ UCLA | Los Angeles | California | 90095-7000 | — |
| N CA Retina Vitreous Assoc | Mountain View | California | 94040 | — |
| East Bay Retina Consultants | Oakland | California | 94609 | — |
| Southern CA Desert Retina Cons | Palm Desert | California | 92211 | — |
| Byers Eye Insitute at Stanford | Palo Alto | California | 94303 | — |
| Retina Consultants, San Diego | Poway | California | 92064 | — |
| University of California, Davis, Eye Center | Sacramento | California | 95817 | — |
| Retinal Consultants Med Group | Sacramento | California | 95841 | — |
| W Coast Retina Med Group Inc | San Francisco | California | 94107 | — |
| UCSF Comprehensive Cancer Ctr; Ophthalmology | San Francisco | California | 94143 | — |
| Orange County Retina Med Group | Santa Ana | California | 92705 | — |
| California Retina Consultants | Santa Barbara | California | 93103 | — |
| Bay Area Retina Associates | Walnut Creek | California | 94598 | — |
| University of Colorado | Aurora | Colorado | 80045 | — |
| Retina Consultants of Southern | Colorado Springs | Colorado | 80909 | — |
| Colorado Retina Associates, PC | Golden | Colorado | 80201 | — |
| Retina Group of New England | New London | Connecticut | 06320 | — |
| Florida Eye Microsurgical Inst | Boynton Beach | Florida | 33426 | — |
| Retina Group of Florida | Fort Lauderdale | Florida | 33308 | — |
| Retina Health Center | Fort Myers | Florida | 33907 | — |
| National Ophthalmic Research Institute | Fort Myers | Florida | 33912 | — |
| Florida Eye Associates | Melbourne | Florida | 32901 | — |
| Bascom Palmer Eye Institute | Naples | Florida | 34103 | — |
| Retina Care Specialists | Palm Beach Gardens | Florida | 33410 | — |
| Bascom Palmer Eye Institute | Palm Beach Gardens | Florida | 33418 | — |
| Retina Specialty Institute | Pensacola | Florida | 32503 | — |
| Fort Lauderdale Eye Institute | Plantation | Florida | 33324 | — |
| Retina Vitreous Assoc of FL | St. Petersburg | Florida | 33711 | — |
| Southern Vitreoretinal Assoc | Tallahassee | Florida | 32308 | — |
| Retina Associates of Florida, LLC | Tampa | Florida | 33609 | — |
| University of South Florida | Tampa | Florida | 33612 | — |
| Southeast Retina Center | Augusta | Georgia | 30909 | — |
| Georgia Retina PC | Marietta | Georgia | 30060 | — |
| Retina Consultants of Hawaii | ‘Aiea | Hawaii | 96701 | — |
| Midwest Eye Institute Northside | Indianapolis | Indiana | 46290 | — |
| Wolfe Eye Clinic | West Des Moines | Iowa | 50266 | — |
| Retina Associates | Shawnee Mission | Kansas | 66204 | — |
| Vitreo Retinal Consultants | Wichita | Kansas | 67214 | — |
| Lahey Clinic Med Ctr | Lexington | Kentucky | 02421 | — |
| Retina Associates of Kentucky | Lexington | Kentucky | 40509 | — |
| Paducah Retinal Center | Paducah | Kentucky | 42001 | — |
| Maine Eye Center | Portland | Maine | 04102 | — |
| The Retina Care Center | Baltimore | Maryland | 21209 | — |
| Wilmer Eye Institute | Baltimore | Maryland | 21287 | — |
| Retina Group of Washington | Chevy Chase | Maryland | 20815 | — |
| Retina Specialists | Towson | Maryland | 21204 | — |
| Tufts Medical Center Research | Boston | Massachusetts | 02111 | — |
| Mass Eye and Ear Infirmary | Boston | Massachusetts | 02114 | — |
| Ophthalmic Consultants of Boston | Boston | Massachusetts | 02114 | — |
| Vitreo-Retinal Associates, PC | Worcester | Massachusetts | 01605 | — |
| University of Michigan, Kellogg Eye Center | Ann Arbor | Michigan | 48105 | — |
| Kresge Eye Institute | Detroit | Michigan | 48201-1423 | — |
| Vitreo-Retinal Associates | Grand Rapids | Michigan | 49546 | — |
| Specialty Eye Institute | Jackson | Michigan | 49202 | — |
| Assoc Retinal Consultants PC | Royal Oak | Michigan | 48073 | — |
| Retina Consultants of Michigan | Southfield | Michigan | 48034 | — |
| Vitreoretinal Surgery | Edina | Minnesota | 55435 | — |
| Lifelong Vision Foundation | Chesterfield | Missouri | 63017 | — |
| Retina Consultants of Nevada | Las Vegas | Nevada | 89123 | — |
| Sierra Eye Associates | Reno | Nevada | 89502 | — |
| Retina Center of New Jersey | Bloomfield | New Jersey | 07003 | — |
| Mid Atlantic Retina - Wills Eye Hospital | Cherry Hill | New Jersey | 08034 | — |
| New Jersey Retina Research Foundation | Edison | New Jersey | 8820 | — |
| Delaware Valley Retina Assoc | Lawrenceville | New Jersey | 08648 | — |
| Retinal & Ophthalmic Cons PC | Northfield | New Jersey | 08225 | — |
| Retina Associates of NJ | Teaneck | New Jersey | 07666 | — |
| Lions Eye Institute | Albany | New York | 12208 | — |
| Long Is. Vitreoretinal Consult | Hauppauge | New York | 11788 | — |
| Opthalmic Consultants of LI | Lynbrook | New York | 11563 | — |
| New York Eye & Ear Infirmary | New York | New York | 10003 | — |
| Vitreous-Retina-Macula | New York | New York | 10022 | — |
| Retina Assoc of Western NY | Rochester | New York | 14620 | — |
| Retina Vit Surgeons/Central NY | Syracuse | New York | 13224 | — |
| West Carolina Retinal AssocPA | Asheville | North Carolina | 28803 | — |
| Char Eye Ear &Throat Assoc | Charlotte | North Carolina | 28210 | — |
| Duke University Eye Center; Vitreoretinal | Durham | North Carolina | 27710 | — |
| Wake Forest Baptist Health Eye Centre | Winston-Salem | North Carolina | 27157 | — |
| Cincinnati Eye Institute | Cincinnati | Ohio | 45242 | — |
| Retina Assoc of Cleveland Inc | Cleveland | Ohio | 44122 | — |
| Cleveland Clinic Foundation; Cole Eye Institute | Cleveland | Ohio | 44195 | — |
| OSU Eye Physicians & Surgeons | Columbus | Ohio | 43212 | — |
| Retina & Vitreous Center of Southern Oregon | Ashland | Oregon | 97520 | — |
| Retina Northwest | Portland | Oregon | 97221 | — |
| Oregon HSU; Casey Eye Institute | Portland | Oregon | 97239 | — |
| Retina Vitreous Consultants | Monroeville | Pennsylvania | 15146 | — |
| Mid Atlantic Retina | Philadelphia | Pennsylvania | 19107 | — |
| Associates in Ophthalmology | West Mifflin | Pennsylvania | 15122 | — |
| Palmetto Retina Center | Florence | South Carolina | 29501 | — |
| Charleston Neuroscience Inst | Ladson | South Carolina | 29456 | — |
| Black Hills Eye Institute | Rapid City | South Dakota | 57701 | — |
| Southeastern Retina Associates Chattanooga | Chattanooga | Tennessee | 37421 | — |
| Charles Retina Institution | Germantown | Tennessee | 38138 | — |
| Tennessee Retina PC. | Nashville | Tennessee | 37203 | — |
| Retina Res Institute of Texas | Abilene | Texas | 79606 | — |
| Texas Retina Associates | Arlington | Texas | 76012 | — |
| Austin Retina Associates | Austin | Texas | 78705 | — |
| Retina Research Center | Austin | Texas | 78705 | — |
| Texas Retina Associates | Dallas | Texas | 75231 | — |
| Retina Consultants of Houston | Houston | Texas | 77030 | — |
| Valley Retina Institute P.A. | McAllen | Texas | 78503 | — |
| Scott and White Hospital | Temple | Texas | 76504 | — |
| Retina Consultants of Houston | The Woodlands | Texas | 77384 | — |
| Strategic Clinical Research Group, LLC | Willow Park | Texas | 76087 | — |
| Retina Associates of Utah | Salt Lake City | Utah | 84107 | — |
| Univ of Virginia Ophthalmology | Charlottesville | Virginia | 22903 | — |
| Eye Surgeons of Richmond Inc. dba Virginia Eye Institute | Richmond | Virginia | 23226 | — |
| Retina Institute of Virginia | Richmond | Virginia | 23235 | — |
| Virginia Retina Center | Warrenton | Virginia | 20186 | — |
| Vitreoretinal Associates of Washington | Bellevue | Washington | 98004 | — |
| Retina Center Northwest | Silverdale | Washington | 98383 | — |
| Spokane Eye Clinical Research | Spokane | Washington | 99204 | — |
| West Virginia University Eye Institute | Morgantown | West Virginia | 26506 | — |
| University of Wisconsin | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 86 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02745119, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 6, 2019 · Synced Oct 18, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02745119 live on ClinicalTrials.gov.