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ClinicalTrials.gov record
Active, not recruiting Phase 2 Interventional Results available

Enzalutamide for Patients With Androgen Receptor Positive Salivary Cancers

ClinicalTrials.gov ID: NCT02749903

Public ClinicalTrials.gov record NCT02749903. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 28, 2026, 1:41 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II Study of Enzalutamide (NSC# 766085) for Patients With Androgen Receptor Positive Salivary Cancers

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This phase II trial studies how well enzalutamide works in treating patients with androgen receptor positive salivary cancers that have spread from where it started to nearby tissue or lymph nodes (locally advanced) or have spread to other places in the body (metastatic) and cannot be removed by surgery. Proteins called androgen receptors bind to androgens (hormones) and may cause tumor cells to grow. Enzalutamide may stop the growth of tumor cells by binding to and blocking androgen receptor proteins.

Study identification

NCT ID
NCT02749903
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Enrollment
46 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 14, 2016 (Actual)
Primary completion
Feb 21, 2019 (Actual)
Completion
Jul 5, 2028 (Estimated)
Last update posted
Oct 7, 2026

2016 – 2028

United States locations

U.S. sites
287
U.S. states
30
U.S. cities
204
Facility City State ZIP Site status
Anchorage Associates in Radiation Medicine Anchorage Alaska 98508 —
Anchorage Radiation Therapy Center Anchorage Alaska 99504 —
Alaska Breast Care and Surgery LLC Anchorage Alaska 99508 —
Alaska Oncology and Hematology LLC Anchorage Alaska 99508 —
Alaska Women's Cancer Care Anchorage Alaska 99508 —
Anchorage Oncology Centre Anchorage Alaska 99508 —
Katmai Oncology Group Anchorage Alaska 99508 —
Providence Alaska Medical Center Anchorage Alaska 99508 —
Kaiser Permanente-Anaheim Anaheim California 92806 —
Kaiser Permanente-Baldwin Park Baldwin Park California 91706 —
Kaiser Permanente-Bellflower Bellflower California 90706 —
Providence Saint Joseph Medical Center/Disney Family Cancer Center Burbank California 91505 —
Kaiser Permanente-Fontana Fontana California 92335 —
Kaiser Permanente-Irvine Irvine California 92618 —
Kaiser Permanente Los Angeles Medical Center Los Angeles California 90027 —
Kaiser Permanente-Cadillac Los Angeles California 90034 —
Kaiser Permanente-Ontario Ontario California 91761 —
Kaiser Permanente - Panorama City Panorama City California 91402 —
Kaiser Permanente-Riverside Riverside California 92505 —
Kaiser Permanente-San Diego Mission San Diego California 92108 —
Kaiser Permanente-San Diego Zion San Diego California 92120 —
Kaiser Permanente-San Marcos San Marcos California 92078 —
Kaiser Permanente-Woodland Hills Woodland Hills California 91367 —
University of Colorado Hospital Aurora Colorado 80045 —
Smilow Cancer Hospital Care Center-Fairfield Fairfield Connecticut 06824 —
Smilow Cancer Center/Yale-New Haven Hospital New Haven Connecticut 06510 —
Yale University New Haven Connecticut 06520 —
Smilow Cancer Hospital Care Center-Trumbull Trumbull Connecticut 06611 —
Beebe Medical Center Lewes Delaware 19958 —
Delaware Clinical and Laboratory Physicians PA Newark Delaware 19713 —
Helen F Graham Cancer Center Newark Delaware 19713 —
Medical Oncology Hematology Consultants PA Newark Delaware 19713 —
Regional Hematology and Oncology PA Newark Delaware 19713 —
Christiana Care Health System-Christiana Hospital Newark Delaware 19718 —
Beebe Health Campus Rehoboth Beach Delaware 19971 —
Nanticoke Memorial Hospital Seaford Delaware 19973 —
Christiana Care Health System-Wilmington Hospital Wilmington Delaware 19801 —
Saint Luke's Mountain States Tumor Institute Boise Idaho 83712 —
Kootenai Medical Center Coeur d'Alene Idaho 83814 —
Saint Luke's Mountain States Tumor Institute - Fruitland Fruitland Idaho 83619 —
Saint Luke's Mountain States Tumor Institute - Meridian Meridian Idaho 83642 —
Saint Luke's Mountain States Tumor Institute - Nampa Nampa Idaho 83686 —
Kootenai Cancer Center Post Falls Idaho 83854 —
Kootenai Cancer Clinic Sandpoint Idaho 83864 —
Saint Luke's Mountain States Tumor Institute-Twin Falls Twin Falls Idaho 83301 —
Rush - Copley Medical Center Aurora Illinois 60504 —
Saint Joseph Medical Center Bloomington Illinois 61701 —
Illinois CancerCare-Bloomington Bloomington Illinois 61704 —
Illinois CancerCare-Canton Canton Illinois 61520 —
Memorial Hospital of Carbondale Carbondale Illinois 62902 —
SIH Cancer Institute Carterville Illinois 62918 —
Illinois CancerCare-Carthage Carthage Illinois 62321 —
Centralia Oncology Clinic Centralia Illinois 62801 —
John H Stroger Jr Hospital of Cook County Chicago Illinois 60612 —
Carle on Vermilion Danville Illinois 61832 —
Cancer Care Specialists of Illinois - Decatur Decatur Illinois 62526 —
Decatur Memorial Hospital Decatur Illinois 62526 —
Carle Physician Group-Effingham Effingham Illinois 62401 —
Crossroads Cancer Center Effingham Illinois 62401 —
Illinois CancerCare-Eureka Eureka Illinois 61530 —
Illinois CancerCare-Galesburg Galesburg Illinois 61401 —
Western Illinois Cancer Treatment Center Galesburg Illinois 61401 —
Illinois CancerCare-Kewanee Clinic Kewanee Illinois 61443 —
Illinois CancerCare-Macomb Macomb Illinois 61455 —
Carle Physician Group-Mattoon/Charleston Mattoon Illinois 61938 —
Illinois CancerCare-Ottawa Clinic Ottawa Illinois 61350 —
Radiation Oncology of Northern Illinois Ottawa Illinois 61350 —
Illinois CancerCare-Pekin Pekin Illinois 61554 —
OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center Pekin Illinois 61554 —
Illinois CancerCare-Peoria Peoria Illinois 61615 —
OSF Saint Francis Radiation Oncology at Peoria Cancer Center Peoria Illinois 61615 —
Methodist Medical Center of Illinois Peoria Illinois 61636 —
OSF Saint Francis Medical Center Peoria Illinois 61637 —
Illinois CancerCare-Peru Peru Illinois 61354 —
Valley Radiation Oncology Peru Illinois 61354 —
Illinois CancerCare-Princeton Princeton Illinois 61356 —
Central Illinois Hematology Oncology Center Springfield Illinois 62702 —
Southern Illinois University School of Medicine Springfield Illinois 62702 —
Springfield Clinic Springfield Illinois 62702 —
Memorial Medical Center Springfield Illinois 62781 —
Cancer Care Specialists of Illinois-Swansea Swansea Illinois 62226 —
Southwest Illinois Health Services LLP Swansea Illinois 62226 —
Carle Cancer Center Urbana Illinois 61801 —
The Carle Foundation Hospital Urbana Illinois 61801 —
Rush-Copley Healthcare Center Yorkville Illinois 60560 —
Deaconess Clinic Downtown Evansville Indiana 47713 —
Franciscan Saint Anthony Health-Michigan City Michigan City Indiana 46360 —
Woodland Cancer Care Center Michigan City Indiana 46360 —
Chancellor Center for Oncology Newburgh Indiana 47630 —
Reid Health Richmond Indiana 47374 —
Iowa Methodist Medical Center Des Moines Iowa 50309 —
Medical Oncology and Hematology Associates-Des Moines Des Moines Iowa 50309 —
Broadlawns Medical Center Des Moines Iowa 50314 —
Iowa Lutheran Hospital Des Moines Iowa 50316 —
University of Iowa/Holden Comprehensive Cancer Center Iowa City Iowa 52242 —
Methodist West Hospital West Des Moines Iowa 50266-7700 —
Oncology Hematology Care Inc-Crestview Crestview Hills Kentucky 41017 —
LSU Health Baton Rouge-North Clinic Baton Rouge Louisiana 70805 —
Louisiana Hematology Oncology Associates LLC Baton Rouge Louisiana 70809 —
Mary Bird Perkins Cancer Center Baton Rouge Louisiana 70809 —
Our Lady of the Lake Physicians Group - Medical Oncology Baton Rouge Louisiana 70809 —
Northshore Oncology Associates-Covington Covington Louisiana 70433 —
Oncology Center of The South Incorporated Houma Louisiana 70360 —
Johns Hopkins University/Sidney Kimmel Cancer Center Baltimore Maryland 21287 —
University of Michigan Comprehensive Cancer Center Ann Arbor Michigan 48109 —
Henry Ford Cancer Institute?Downriver Brownstown Michigan 48183 —
Henry Ford Macomb Hospital-Clinton Township Clinton Township Michigan 48038 —
Henry Ford Medical Center-Fairlane Dearborn Michigan 48126 —
Henry Ford Hospital Detroit Michigan 48202 —
Allegiance Health Jackson Michigan 49201 —
Henry Ford Medical Center-Columbus Novi Michigan 48377 —
Henry Ford West Bloomfield Hospital West Bloomfield Michigan 48322 —
Sanford Joe Lueken Cancer Center Bemidji Minnesota 56601 —
Fairview Ridges Hospital Burnsville Minnesota 55337 —
Mercy Hospital Coon Rapids Minnesota 55433 —
Fairview-Southdale Hospital Edina Minnesota 55435 —
Unity Hospital Fridley Minnesota 55432 —
Fairview Maple Grove Medical Center Maple Grove Minnesota 55369 —
Minnesota Oncology Hematology PA-Maplewood Maplewood Minnesota 55109 —
Saint John's Hospital - Healtheast Maplewood Minnesota 55109 —
Abbott-Northwestern Hospital Minneapolis Minnesota 55407 —
Hennepin County Medical Center Minneapolis Minnesota 55415 —
Health Partners Inc Minneapolis Minnesota 55454 —
New Ulm Medical Center New Ulm Minnesota 56073 —
North Memorial Medical Health Center Robbinsdale Minnesota 55422 —
Mayo Clinic Rochester Minnesota 55905 —
Park Nicollet Clinic - Saint Louis Park Saint Louis Park Minnesota 55416 —
Regions Hospital Saint Paul Minnesota 55101 —
United Hospital Saint Paul Minnesota 55102 —
Saint Francis Regional Medical Center Shakopee Minnesota 55379 —
Lakeview Hospital Stillwater Minnesota 55082 —
Ridgeview Medical Center Waconia Minnesota 55387 —
Rice Memorial Hospital Willmar Minnesota 56201 —
Minnesota Oncology Hematology PA-Woodbury Woodbury Minnesota 55125 —
Fairview Lakes Medical Center Wyoming Minnesota 55092 —
Parkland Health Center-Bonne Terre Bonne Terre Missouri 63628 —
Saint Francis Medical Center Cape Girardeau Missouri 63703 —
Southeast Cancer Center Cape Girardeau Missouri 63703 —
Siteman Cancer Center at Saint Peters Hospital City of Saint Peters Missouri 63376 —
Siteman Cancer Center at West County Hospital Creve Coeur Missouri 63141 —
Capital Region Southwest Campus Jefferson City Missouri 65109 —
Sainte Genevieve County Memorial Hospital Sainte Genevieve Missouri 63670 —
Washington University School of Medicine St Louis Missouri 63110 —
Siteman Cancer Center-South County St Louis Missouri 63129 —
Missouri Baptist Medical Center St Louis Missouri 63131 —
Missouri Baptist Sullivan Hospital Sullivan Missouri 63080 —
Missouri Baptist Outpatient Center-Sunset Hills Sunset Hills Missouri 63127 —
Community Hospital of Anaconda Anaconda Montana 59711 —
Billings Clinic Cancer Center Billings Montana 59101 —
Saint Vincent Healthcare Billings Montana 59101 —
Bozeman Deaconess Hospital Bozeman Montana 59715 —
Saint James Community Hospital and Cancer Treatment Center Butte Montana 59701 —
Benefis Healthcare- Sletten Cancer Institute Great Falls Montana 59405 —
Great Falls Clinic Great Falls Montana 59405 —
Saint Peter's Community Hospital Helena Montana 59601 —
Kalispell Regional Medical Center Kalispell Montana 59901 —
Saint Patrick Hospital - Community Hospital Missoula Montana 59802 —
Community Medical Hospital Missoula Montana 59804 —
Nebraska Methodist Hospital Omaha Nebraska 68114 —
Memorial Sloan Kettering Basking Ridge Basking Ridge New Jersey 07920 —
Memorial Sloan Kettering Monmouth Middletown New Jersey 07748 —
Morristown Medical Center Morristown New Jersey 07960 —
Overlook Hospital Summit New Jersey 07902 —
Roswell Park Cancer Institute Buffalo New York 14263 —
Memorial Sloan Kettering Commack Commack New York 11725 —
Memorial Sloan Kettering Westchester East White Plains New York 10604 —
Northwell Health/Center for Advanced Medicine Lake Success New York 11042 —
Memorial Sloan Kettering Cancer Center New York New York 10065 —
Memorial Sloan Kettering Rockville Centre Rockville Centre New York 11570 —
Sanford Bismarck Medical Center Bismarck North Dakota 58501 —
Roger Maris Cancer Center Fargo North Dakota 58122 —
Sanford Broadway Medical Center Fargo North Dakota 58122 —
Indu and Raj Soin Medical Center Beavercreek Ohio 45431 —
Dayton Physicians LLC-Miami Valley South Centerville Ohio 45459 —
Miami Valley Hospital South Centerville Ohio 45459 —
Oncology Hematology Care Inc-Eden Park Cincinnati Ohio 45202 —
Oncology Hematology Care Inc-Mercy West Cincinnati Ohio 45211 —
Oncology Hematology Care Inc - Anderson Cincinnati Ohio 45230 —
Oncology Hematology Care Inc-Kenwood Cincinnati Ohio 45236 —
Oncology Hematology Care Inc-Blue Ash Cincinnati Ohio 45242 —
Ohio State University Comprehensive Cancer Center Columbus Ohio 43210 —
Good Samaritan Hospital - Dayton Dayton Ohio 45406 —
Miami Valley Hospital Dayton Ohio 45409 —
Dayton Physicians LLC-Samaritan North Dayton Ohio 45415 —
Miami Valley Hospital North Dayton Ohio 45415 —
Oncology Hematology Care Inc-Healthplex Fairfield Ohio 45014 —
Armes Family Cancer Center Findlay Ohio 45840 —
Blanchard Valley Hospital Findlay Ohio 45840 —
Orion Cancer Care Findlay Ohio 45840 —
Atrium Medical Center-Middletown Regional Hospital Franklin Ohio 45005-1066 —
Dayton Physicians LLC-Atrium Franklin Ohio 45005 —
Dayton Physicians LLC-Wayne Greenville Ohio 45331 —
Wayne Hospital Greenville Ohio 45331 —
Greater Dayton Cancer Center Kettering Ohio 45409 —
First Dayton Cancer Care Kettering Ohio 45420 —
Kettering Medical Center Kettering Ohio 45429 —
Dayton Physicians LLC-Signal Point Middletown Ohio 45042 —
Dayton Physicians LLC-Wilson Sidney Ohio 45365 —
Springfield Regional Cancer Center Springfield Ohio 45504 —
Springfield Regional Medical Center Springfield Ohio 45505 —
Dayton Physicians LLC-Upper Valley Troy Ohio 45373 —
Upper Valley Medical Center Troy Ohio 45373 —
Cancer Centers of Southwest Oklahoma Research Lawton Oklahoma 73505 —
University of Oklahoma Health Sciences Center Oklahoma City Oklahoma 73104 —
Saint Charles Health System Bend Oregon 97701 —
Clackamas Radiation Oncology Center Clackamas Oregon 97015 —
Providence Oncology and Hematology Care Southeast Clackamas Oregon 97015 —
Bay Area Hospital Coos Bay Oregon 97420 —
Providence Newberg Medical Center Newberg Oregon 97132 —
Providence Willamette Falls Medical Center Oregon City Oregon 97045 —
Providence Portland Medical Center Portland Oregon 97213 —
Providence Saint Vincent Medical Center Portland Oregon 97225 —
Saint Charles Health System-Redmond Redmond Oregon 97756 —
UPMC-Heritage Valley Health System Beaver Beaver Pennsylvania 15009 —
Christiana Care Health System-Concord Health Center Chadds Ford Pennsylvania 19317 —
UPMC Cancer Centers - Arnold Palmer Pavilion Greensburg Pennsylvania 15601 —
Penn State Milton S Hershey Medical Center Hershey Pennsylvania 17033-0850 —
UPMC-Johnstown/John P. Murtha Regional Cancer Center Johnstown Pennsylvania 15901 —
UPMC Cancer Center at UPMC McKeesport McKeesport Pennsylvania 15132 —
UPMC-Coraopolis/Heritage Valley Radiation Oncology Moon Township Pennsylvania 15108 —
UPMC-Magee Womens Hospital Pittsburgh Pennsylvania 15213 —
UPMC-Presbyterian Hospital Pittsburgh Pennsylvania 15213 —
UPMC-Saint Margaret Pittsburgh Pennsylvania 15215 —
University of Pittsburgh Cancer Institute (UPCI) Pittsburgh Pennsylvania 15232 —
UPMC-Shadyside Hospital Pittsburgh Pennsylvania 15232 —
UPMC-Passavant Hospital Pittsburgh Pennsylvania 15237 —
UPMC-Saint Clair Hospital Cancer Center Pittsburgh Pennsylvania 15243 —
UPMC Cancer Center at UPMC Northwest Seneca Pennsylvania 16346 —
UPMC Uniontown Hospital Radiation Oncology Uniontown Pennsylvania 15401 —
UPMC Washington Hospital Radiation Oncology Washington Pennsylvania 15301 —
UPMC Susquehanna Williamsport Pennsylvania 17701 —
Medical University of South Carolina Charleston South Carolina 29425 —
Greenville Health System Cancer Institute-Laurens Clinton South Carolina 29325 —
Greenville Health System Cancer Institute-Easley Easley South Carolina 29640 —
Greenville Health System Cancer Institute-Butternut Greenville South Carolina 29605 —
Greenville Health System Cancer Institute-Faris Greenville South Carolina 29605 —
Greenville Memorial Hospital Greenville South Carolina 29605 —
Greenville Health System Cancer Institute-Eastside Greenville South Carolina 29615 —
Greenville Health System Cancer Institute-Greer Greer South Carolina 29650 —
Greenville Health System Cancer Institute-Seneca Seneca South Carolina 29672 —
Greenville Health System Cancer Institute-Spartanburg Spartanburg South Carolina 29307 —
Sanford Cancer Center Oncology Clinic Sioux Falls South Dakota 57104 —
Sanford USD Medical Center - Sioux Falls Sioux Falls South Dakota 57117-5134 —
Inova Fairfax Hospital-Woodburn Infusion Clinic Annandale Virginia 22003 —
Inova Fairfax Hospital Falls Church Virginia 22042 —
Providence Regional Cancer System-Aberdeen Aberdeen Washington 98520 —
Cancer Care Center at Island Hospital Anacortes Washington 98221 —
Swedish Cancer Institute-Eastside Oncology Hematology Bellevue Washington 98005 —
PeaceHealth Saint Joseph Medical Center Bellingham Washington 98225 —
Providence Regional Cancer System-Centralia Centralia Washington 98531 —
Swedish Medical Center-Edmonds Edmonds Washington 98026 —
Providence Regional Cancer Partnership Everett Washington 98201 —
Swedish Cancer Institute-Issaquah Issaquah Washington 98029 —
Kadlec Clinic Hematology and Oncology Kennewick Washington 99336 —
Providence Regional Cancer System-Lacey Lacey Washington 98503 —
PeaceHealth Saint John Medical Center Longview Washington 98632 —
Minor and James Medical PLLC Seattle Washington 98104 —
Pacific Gynecology Specialists Seattle Washington 98104 —
Swedish Medical Center-Ballard Campus Seattle Washington 98107 —
Kaiser Permanente Washington Seattle Washington 98112 —
Swedish Medical Center-First Hill Seattle Washington 98122-4307 —
Swedish Medical Center-Cherry Hill Seattle Washington 98122-5711 —
PeaceHealth United General Medical Center Sedro-Woolley Washington 98284 —
Providence Regional Cancer System-Shelton Shelton Washington 98584 —
Rockwood Cancer Treatment Center-DHEC-Downtown Spokane Washington 99204 —
Rockwood North Cancer Treatment Center Spokane Washington 99218 —
Rockwood Clinic Cancer Treatment Center-Valley Spokane Valley Washington 99216 —
PeaceHealth Southwest Medical Center Vancouver Washington 98664 —
Providence Saint Mary Regional Cancer Center Walla Walla Washington 99362 —
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital Yakima Washington 98902 —
Providence Regional Cancer System-Yelm Yelm Washington 98597 —
Marshfield Clinic-Chippewa Center Chippewa Falls Wisconsin 54729 —
Marshfield Clinic Cancer Center - Eau Claire Eau Claire Wisconsin 54701 —
Marshfield Clinic Cancer Center at Sacred Heart Eau Claire Wisconsin 54701 —
Gundersen Lutheran Medical Center La Crosse Wisconsin 54601 —
Marshfield Clinic - Ladysmith Center Ladysmith Wisconsin 54848 —
Marshfield Clinic Marshfield Wisconsin 54449 —
Marshfield Clinic-Minocqua Center Minocqua Wisconsin 54548 —
Cancer Center of Western Wisconsin New Richmond Wisconsin 54017 —
Marshfield Clinic-Rice Lake Center Rice Lake Wisconsin 54868 —
Marshfield Clinic Stevens Point Center Stevens Point Wisconsin 54482 —
Marshfield Clinic-Wausau Center Wausau Wisconsin 54401 —
Marshfield Clinic - Weston Center Weston Wisconsin 54476 —
Marshfield Clinic - Wisconsin Rapids Center Wisconsin Rapids Wisconsin 54494 —
Big Horn Basin Cancer Center Cody Wyoming 82414 —
Billings Clinic-Cody Cody Wyoming 82414 —
Welch Cancer Center Sheridan Wyoming 82801 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02749903, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 7, 2026 · Synced Oct 28, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02749903 live on ClinicalTrials.gov.

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