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Completed Phase 2 Interventional Results available

Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial of BEKINDA (Ondansetron 12 mg Bimodal Release Tablets) for Diarrhea Predominant Irritable Bowel Syndrome (IBS-D)

ClinicalTrials.gov ID: NCT02757105

Public ClinicalTrials.gov record NCT02757105. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 6, 2026, 11:50 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Randomized, Double-blind, Placebo-controlled, Phase 2 Trial of BEKINDA (Ondansetron 12 mg Bimodal Release Tablets) for Diarrhea Predominant Irritable Bowel Syndrome (IBS-D)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a randomized, double-blind, placebo-controlled, 2-arm parallel group study. After qualifying for the study and signing informed consent, patients will undergo a two-week observation period during which stool consistency and frequency data and symptom data will be collected. Patients will then be randomized 60:40 to RHB-102 12 mg (BEKINDA) or placebo. Patients will continue on treatment for 8 weeks. Each medication will be given once daily.

Study identification

NCT ID
NCT02757105
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
RedHill Biopharma Limited
Industry
Enrollment
127 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 80 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 18, 2016
Primary completion
Jun 15, 2017
Completion
Jul 13, 2017
Last update posted
Aug 27, 2018

2016 – 2017

United States locations

U.S. sites
16
U.S. states
9
U.S. cities
15
Facility City State ZIP Site status
Clinical Research Associates, LLC Huntsville Alabama 35801
E Squared Research, Inc. Huntsville Alabama 35801
Endoscoopy Center of AR Little Rock Arkansas 72212
Arkansas Gastroenterology, P.A. North Little Rock Arkansas 72117
Prx Clinical Garden Grove California 92840
Providence Clinical Research North Hollywood California 91606
Shahram Jacobs MD, Inc. Sherman Oaks California 91403
Advanced Rx Clinical Research Group, Inc. Westminster California 92683
Bristol Hospital Dba Connecticut Gastroenterology Institute Bristol Connecticut 06010
Clinical Research of Homestead Homestead Florida 33030
PMG Research of Winston-Salem Winston-Salem North Carolina 27103
Great Lakes Medical Research Mentor Ohio 44060
Clinsearch Chattanooga Tennessee 37421
New Phase Research & Development Knoxville Tennessee 37909
Aztec Medical Research, LLC Channelview Texas 77530
Gastroenterology Research of San Antonio San Antonio Texas 78229

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02757105, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 27, 2018 · Synced Sep 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02757105 live on ClinicalTrials.gov.

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