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Completed Phase 3 Interventional Results available

Evaluation of the Efficacy and Safety of Two Dosing Regimens of Olokizumab (OKZ), Compared to Placebo, in Subjects With Rheumatoid Arthritis (RA) Who Were Taking an Existing Medication Called a Tumour Necrosis Factor Alpha Inhibitor But Had Active Disease

ClinicalTrials.gov ID: NCT02760433

Public ClinicalTrials.gov record NCT02760433. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 23, 2026, 4:18 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-blind, Parallel-group, Placebo-controlled, Multicenter Phase III Study of the Efficacy and Safety of Olokizumab in Subjects With Moderately to Severely Active Rheumatoid Arthritis Inadequately Controlled by Tumor Necrosis Factor Alpha (TNF-α) Inhibitor Therapy

Study identification

NCT ID
NCT02760433
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
R-Pharm International, LLC
Industry
Enrollment
368 participants

Conditions and interventions

Interventions

  • Olokizumab Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 24, 2017
Primary completion
Sep 11, 2019
Completion
Sep 30, 2019
Last update posted
Sep 20, 2023

2017 – 2019

United States locations

U.S. sites
50
U.S. states
22
U.S. cities
47
Facility City State ZIP Site status
Arizona Arthritis & Rheumatology Associates, P.C. Phoenix Arizona 85032
CHI St. Vincent Hot Springs Hot Springs Arkansas 71913
Medvin Clinical Research Covina California 91722
TriWest Research Associates, LLC El Cajon California 92020-4124
Saint Jude Heritage Medical Grp Fullerton California 92835
С V Mehta MD Med Corp. Hemet California 92543
Advanced Medical Research, LLC Lakewood California 90623
Stanford University School of Medicine Palo Alto California 94304
Riverside Medical Clinic Riverside California 92506
East Bay Rheumatology Medical Group, Inc. San Leandro California 94578
Inland Rheumatology Clinical Trials, Inc. Upland California 91786
Denver Arthritis Clinic Denver Colorado 80230
Javed Rheumatology Associates Newark Delaware 19713
RASF - Clinical Research Center Boca Raton Florida 33486
Suncoast Research Group LLC Miami Florida 33135
Omega Research Consultants Orlando Florida 32810
Family Clinical Trials, LLC. Pembroke Pines Florida 33026
AdventHealth Medical Group, PA Tampa Florida 33614
Institute of Arthritis Research Idaho Falls Idaho 83404
University of Kansas Hospital Kansas City Kansas 66160
Graves Gilbert Clinic Bowling Green Kentucky 42101
The Arthritis & Diabetes Clinic, Inc. Monroe Louisiana 71203
Klein and Associates, M.D., P.A. Hagerstown Maryland 21740
The Center for Rheumatology and Bone Research Wheaton Maryland 20902
Clinical Pharmacology Study Group Worcester Massachusetts 01605
Glacier View Research Instutute-Rheumatology Kalispell Montana 59901
Arthritis & Osteoporosis Associates, PA Freehold New Jersey 07728
Lovelace Scientific Resources, Inc. Albuquerque New Mexico 87114
NYU Langone Ambulatory Care New York New York 11201
Medication Management, LLC Greensboro North Carolina 27408
Cape Fear Arthritis Care Leland North Carolina 28451
Carolina Arthritis Associates Wilmington North Carolina 28401
Trinity Medical Group Minot North Dakota 58701
Cincinnati Rheumatic Disease Study Group Cincinnati Ohio 45242
STAT Research, Inc. Dayton Ohio 45417
Clinical Research Source, Inc. Perrysburg Ohio 43606
Arthritis Group Philadelphia Pennsylvania 19152
Low Country Research Center Charleston South Carolina 29486
Amarillo Center for Clinical Research Amarillo Texas 79124
Austin Regional Clinic, P.A. Austin Texas 78731
Accurate Clinical Research, Inc. Baytown Texas 77521
Precision Comprehensive Clinical Research Solutions Grapevine Texas 76034
Therapeutic Concepts Rheumatology, LLC Houston Texas 77004
Rheumatology Clinic of Houston, P.A. Houston Texas 77065
Accurate Clinical Research, Inc. Houston Texas 77089
Pioneer Research Solutions, Inc. Houston Texas 77429
Accurate Clinical Research, Inc. League City Texas 77573
Endocrinology, Internal Medicine Lubbock Texas 79410
Dr. Alex De Jesus Rheumatology, P.A. San Antonio Texas 78229
Advanced Rheumatology of Houston Woodville Texas 77382

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 66 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02760433, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 20, 2023 · Synced Jul 23, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02760433 live on ClinicalTrials.gov.

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