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Completed Not applicable Interventional Results available

The MOTS (Medication Overuse Treatment Strategy) Trial

ClinicalTrials.gov ID: NCT02764320

Public ClinicalTrials.gov record NCT02764320. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Nov 2, 2026, 12:49 PM EST

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Determining the Optimal Treatment Strategy for Patients Who Have Chronic Migraine With Medication Overuse

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

There are two commonly used treatment strategies for treating patients who have chronic migraine with medication overuse. This study will compare the outcomes amongst patients randomized to one of the two treatment strategies.

Study identification

NCT ID
NCT02764320
Recruitment status
Completed
Study type
Interventional
Phase
Not applicable
Lead sponsor
Mayo Clinic
Other
Enrollment
720 participants

Conditions and interventions

Eligibility (public fields only)

Age range
21 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 9, 2017 (Actual)
Primary completion
Mar 31, 2021 (Actual)
Completion
Mar 31, 2021 (Actual)
Last update posted
Nov 12, 2021

2017 – 2021

United States locations

U.S. sites
29
U.S. states
15
U.S. cities
24
Facility City State ZIP Site status
Northern Arizona Healthcare Medical Group Flagstaff Arizona 86001 —
Mayo Clinic in Arizona Headache Center Phoenix Arizona 85054 —
Mayo Clinic in Arizona Neurology Center Phoenix Arizona 85054 —
Honor Health Neurology Scottsdale Arizona 85251 —
Mayo Clinic Thunderbird Scottsdale Arizona 85260 —
Keck Medical Center of USC Los Angeles California 90033 —
University of Colorado Denver Headache Center Aurora Colorado 80045 —
University of Colorado Denver Primary Center Denver Colorado 80238 —
Blue Sky Neurology Greenwood Village Colorado 80111 —
Memorial Healthcare Hollywood Florida 33021 —
University of Miami Miller School of Medicine Miami Florida 33136 —
Norton Neurology Louisville Kentucky 40207 —
Brigham Women's Hospital Headache Clinic Boston Massachusetts 02130 —
Brigham Women's Hospital Neurology Clinic Boston Massachusetts 02130 —
Henry Ford Allegiance Health Jackson Michigan 49201 —
Mayo Clinic Headache Center Rochester Minnesota 55905 —
The Headache Center Ridgeland Mississippi 39157 —
Clinvest Research Springfield Missouri 65801 —
University of Cincinnati Neurology Cincinnati Ohio 45417 —
Cleveland Clinic Cleveland Ohio 44195 —
University of Cincinnati Headache Center Dayton Ohio 45417 —
Toledo Clinic Adult Neurology Toledo Ohio 43623 —
Thomas Jefferson University Hospital Headache Center Philadelphia Pennsylvania 19107 —
Preferred Headache Center Pittsburgh Pennsylvania 15236 —
University of Utah Primary Care Salt Lake City Utah 84106 —
University of Utah General Neurology Salt Lake City Utah 84108 —
University of Utah Headache Center Salt Lake City Utah 84132 —
University of Washington Seattle Washington 98195 —
West Virginia University Neurology Morgantown West Virginia 26506 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02764320, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 12, 2021 · Synced Nov 2, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02764320 live on ClinicalTrials.gov.

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