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Completed No phase listed Observational Accepts healthy volunteers

Testing Native Language Neural Commitment at the Subcortical Level

ClinicalTrials.gov ID: NCT02774356

Public ClinicalTrials.gov record NCT02774356. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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Official title

Testing Native Language Neural Commitment at the Subcortical Level: Links Between Brainstem Frequency Following Responses and Behavioral Perception for Lexical Tones

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This mentored student research project is funded by the Graduate Research Partnership Program with a projected timeline for data collection in the summer of 2015. Previous research has shown that language experience alters the way the human brain processes speech information. This phenomenon takes place very early in life and is referred to as Native Language Neural Commitment. For instance, as the Japanese language does not have the l-r speech sound contrast, Japanese infants start to show difficulty in hearing differences between the English l and r sounds at 12 months of age but not when they were at 6 months old. Learning the l-r distinction later in life proves to be very difficult for the Japanese school students and adults. Brain imaging studies have further revealed specific brain regions that are changed by language learning. But the evidence in support of the Native Language Neural Commitment theory is based on cortical-level measures. The proposed study extends the measurement to the subcortical level at the brainstem. The target language that the investigators are interested in studying is Mandarin Chinese, which is known for its use of lexical tones to express different words. For instance, the Chinese syllable "ma" means "mother" when it is spoken with a flat tone, and it means "hemp" when spoken with a rising tone. English, by contrast, does not employ lexical tones, and it is considered a non-tonal language. Does the Chinese learning experience fundamental change the way that pitch information is coded in the human brain? Does it happen at both cortical and subcortical levels? Previous research has shown evidence for a positive answer to both questions. But the direct evidence for brain-behavior correlations at the subcortical level is still missing. The proposed cross-language study will test Chinese-speaking and English-speaking adults to investigate Native Language Neural Commitment at the subcortical level. The investigators are interested in differences in the two subject populations by examining the relationship between brainstem pitch tracking and behavioral pitch perception in linguistic and nonlinguistic stimuli. The results of the proposed project will contribute to the understanding the role of the subcortical brainstem in Native Language Neural Commitment, which have significant implications for the development of auditory/speech training programs and assessment tools utilizing the brainstem frequency following measure to monitor progress in second language learning and test clinical populations.

Study identification

NCT ID
NCT02774356
Recruitment status
Completed
Study type
Observational
Phase
Not listed
Lead sponsor
University of Minnesota
Other
Enrollment
36 participants

Conditions and interventions

Interventions

Not listed

Eligibility (public fields only)

Age range
18 Years to 50 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 30, 2015
Primary completion
Nov 30, 2016
Completion
Nov 30, 2016
Last update posted
Jan 17, 2017

2015 – 2016

United States locations

U.S. sites
1
U.S. states
1
U.S. cities
1
Facility City State ZIP Site status
Zhang Lab at Department of Speech-Language-Hearing Sciences Minneapolis Minnesota 55455

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02774356, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 17, 2017 · Synced Sep 5, 2026

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